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  6. Filaggrin Antibody (FLG/1562) - Azide and BSA Free, Novus Biologicals™

Filaggrin Antibody (FLG/1562) - Azide and BSA Free, Novus Biologicals™
SDP

Catalog No. NB254362200 Shop All R&D Systems Products
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NB254362200 200 μg
NB254362100 100 μg
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Catalog No. NB254362200 Supplier Novus Biologicals Supplier No. NBP254362200UG

Description

Mouse Monoclonal Antibody

Filaggrin Monoclonal antibody specifically detects Filaggrin in Human samples. It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, CyTOF-ready.

Specifications

Antigen Filaggrin
Applications Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), CyTOF
Classification Monoclonal
Clone FLG/1562
Concentration 1 mg/mL
Conjugate Unconjugated
Dilution Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 1 - 2 ug/ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, CyTOF-ready
Formulation PBS with No Preservative
Gene Alias ATOD2, epidermal filaggrin, filaggrin, Profilaggrin
Gene Symbols FLG
Host Species Mouse
Immunogen Recombinant human Filaggrin protein fragment (aa 198-288) (exact sequence is proprietary)
Purification Method Protein A or G purified
Quantity 200 μg
Regulatory Status RUO
Research Discipline Cytoskeleton Markers
Primary or Secondary Primary
Gene ID (Entrez) 2312
Test Specificity Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.
Target Species Human
Content And Storage Store at -20 to -80C. Avoid freeze-thaw cycles.
Form Purified
Isotype IgG1 κ
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For Research Use Only

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