IGFBP7 Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
500P234BT25	Invitrogen™ 500P234BT25UG	25 μg
500P234BT50	Invitrogen™ 500P234BT50UG	50 μg
50-271-8587	Invitrogen™ 500P234BT500UG	500 μg

Description

AA Sequence of recombinant protein: SSSDTCGPCE PASCPPLPPL GCLLGETRDA CGCCPMCARG EGEPCGGGGA GRGYCAPGME CVKSRKRRKG KAGAAAGGPG VSGVCVCKSR YPVCGSDGTT YPSGCQLRAA SQRAESRGEK AITQVSKGTC EQGPSIVTPP KDIWNVTGAQ VYLSCEVIGI PTPVLIWNKV KRGHYGVQRT ELLPGDRDNL AIQTRGGPEK HEVTGWVLVS PLSKEDAGEY ECHASNSQGQ ASASAKITVV DALHEIPVKK GEGAEL. Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human IGF-BP7. Anti-Human IGF-BP7-specific antibody was purified by affinity chromatography and then biotinylated. Sandwich ELISA: To detect hIGF-BP7 by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required. This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human IGF-BP7 (500-P234) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant hIGF-BP7. Western Blot: To detect hIGF-BP7 by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant hIGF-BP7 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions. 500-P234BT-1MG will be provided as 2 x 500 μg

This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm.

Specifications

• Antigen: IGFBP7
• Applications: ELISA, Western Blot
• Conjugate: Biotin
• Host Species: Rabbit
• Target Species: Human
• Gene Accession No.: Q16270
• Gene ID (Entrez): 3490
• Immunogen: E.coli-derived Recombinant Human IGF-BP7.
• Purification Method: Antigen affinity chromatography
• Gene: IGFBP7

• Concentration: 0.1-1.0 mg/mL
• Classification: Polyclonal
• Form: Lyophilized
• Regulatory Status: RUO
• Formulation: PBS with no preservative
• Gene Alias: AGM; angiomodulin; FSTL2; IBP7; IBP-7; IGF-binding protein 7; IGFBP; IGFBP rP1; Igfbp7; IGFBP-7; IGFBP-7v; IGFBPRP1; IGFBP-rP1; Insulin like growth factor binding protein; insulin like growth factor binding protein 7; insulin-like growth factor binding protein 7; insulin-like growth factor-binding protein 7; Mac25; MAC25 protein; PGI2-stimulating factor; prostacyclin-stimulating factor; PSF; RAMSVPS; TAF; Tumor-derived adhesion factor
• Gene Symbols: IGFBP7
• Primary or Secondary: Primary
• Content And Storage: -20°C