Epredia™ Lab Vision™ Caspase 3 (CPP32) Ab-4 Rabbit Polyclonal Antibody, biotin labeled with BSA and azide

Ensure accurate, reproducible results in immunohistochemistry, western blotting and immunoprecipitation procedures.

Catalog Number	Mfr. No.	Quantity	Conjugate	Form	Formulation
RB1197B0	Epredia™ RB1197B0	100 μL	Biotin	Concentrated	Purified with BSA and Azide
RB1197P0	Epredia™ RB1197P0	100 μL	Unconjugated	Concentrated	Purified with BSA and Azide
RB1197B1	Epredia™ RB1197B1	500 μL	Biotin	Concentrated	Purified with BSA and Azide
RB1197P1	Epredia™ RB1197P1	500 μL	Unconjugated	Concentrated	Purified with BSA and Azide
RB1197P1ABX	Epredia™ RB1197P1ABX	500 μL	Unconjugated	Concentrated	Purified w/o BSA and Azide
RB1197B	Epredia™ RB1197B	1 mL	Biotin	Concentrated	Purified with BSA and Azide
RB1197P	Epredia™ RB1197P	1 mL	Unconjugated	Concentrated	Purified with BSA and Azide
RB1197PABX	Epredia™ RB1197PABX	1 mL	Unconjugated	Concentrated	Purified w/o BSA and Azide
RB1197R1	Epredia™ RB1197R1	1 mL	Unconjugated	Prediluted	Ready-to-use for IHC (UVLP)
RB1197R7	Epredia™ RB1197R7	7 mL	Unconjugated	Prediluted	Ready-to-use

Description

Caspase 3 is ubiquitously expressed and like other caspases is synthesized as an inactive (32 kDa) proenzyme. Upon activation, Caspase 3 is cleaved at Asp28-Ser29 and Asp175-Ser176 thereby generating two subunits of 17 kDa and 12 kDa, respectively. Recent studies have implicated that Caspase 3 is associated with the induction of apoptosis. Activation of Caspase 3 occurs in response to a variety of apoptotic inducers including Fas-mediated apoptosis.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human, Mouse, Rat, Monkey, Rabbit, Hamster, Cow, Sheep, Pig and Dog. Others not tested.

Epitope: Not determined

Immunogen: Recombinant full-length human caspase 3 protein

Molecular Weight: 32 kDa

Positive Control: Jurkat cells, Tonsil

Cellular Localization: Predominantly cytoplasmic with some nuclear staining

Recommended for:

• Immunohistochemistry (Formalin/paraffin)
• Western Blotting
• Immunoprecipitation (Denatured verified)

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: Caspase 3 (CPP32) Ab-4
• Classification: Polyclonal
• Regulatory Status: RUO
• Target Species: Bovine, Canine, Hamster, Human, Mouse, Non-human Primate, Pig, Rabbit, Rat
• Isotype: IgG

• Applications: Immunoprecipitation, Western Blot
• Host Species: Rabbit
• Research Discipline: Apoptosis
• Immunogen: Recombinant full length human caspase 3 protein
• Primary or Secondary: Primary