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Lab Vision™ Mouse anti-Human CD59/MACIF/MIRL/Protectin Monoclonal Antibody, Clone: BRA-10G

Mouse Monoclonal Antibody

Specifications

Antigen CD59/MACIF/MIRL/Protectin Ab-2
Format Purified
Host Species Murine
Immunogen Human K562 tumor cells
Isotype IgG1 κ
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Products 3
Catalog Number Mfr. No. Concentration Conjugate Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Concentration Conjugate Quantity Price Quantity & Availability  
MS507P0
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Epredia
MS507P0
200μg/mL 100μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
MS507P1ABX
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Epredia
MS507P1ABX
1mg/mL 100μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
MS507PABX
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Epredia
MS507PABX
1mg/mL 200μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
Description

Description

CD59 (also known as membrane attack complex inhibition factor (MACIF), membrane inhibitor of reactive lysis (MIRL), homologous restriction factor (HRF20), and Protectin) is a glycosyl phosphatidyl-inositol (GPI)-anchored cell surface protein. CD59 is widely distributed on cells in all tissues. It inhibits formation of MAC, thus protecting cells from complement mediated lysis. The expression of CD59 on erythrocytes is important for their survival. Genetic defects in GPI-anchor attachment that cause a reduction or loss of CD59 and CD55 on erythrocytes produce the symptoms of the disease paroxysmal hemoglobulinuria (PNH).

Host Species: Mouse
Clone: BRA-10G
Isotype: IgG1/κ
Cross Reactivity: Human, Others not-known
Epitope: Not determined
Immunogen: Human K562 tumor cells
Molecular Weight: 20kDa
Positive Control: Daudi, CEM, K562, Jurkat, Raji, and human lymphocytes. Lymph node or tonsil.
Cellular Localization: Cell membrane

Flow Cytometry, Immunohistochemistry, Immunoprecipitation

Abbreviations: AP=Affinity Purification, ChIP=Chromatin IP, CM=Confocal Microscopy, DB=Dot Blot, EIA=ELISA, EM=Electron Microscopy, FC=Flow Cytometry, GS=Gel Supershift, IC=Immunocytochemistry, IF=Immunofluorescence, IH=Immunohistology/Immunohistochemistry, IP=Immunoprecipitation, IPK=IP Kinase Assay, KA=Kinase Assay, NEUT=Neutralization, PIA=Peptide Inhibition Assay, RIA=Radioimmunossay, TCA=T Cell Activation, WB=Western Blotting, Species: Am=Amphibian, Av=Avian, B=Bovine, Ca=Cat ,Ck=Chicken, D=Dog, Dr=Deer, Ds=Drosophila, El=Elk, Fg=Frog, Fs=Fish, Ft=Ferret, G=Goat, Gp=Guinea Pig, H=Horse, Hm=Hamster, Hu=Human, K=Kangaroo, Ms=Mouse, Nhp=Non-Human Primate, O=Ovine, P=Porcine, Rb=Rabbit, Rp=Reptile, Rt=Rat, Ys=Yeast, Xn=Xenopus, (wk)=cross reacts weakly

Specifications

Specifications

CD59/MACIF/MIRL/Protectin Ab-2
Murine
IgG1 κ
Primary
Purified
Human K562 tumor cells
Monoclonal
SDS
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