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p170/p-Glycoprotein/MDR Ab-2 Mouse Monoclonal Antibody, Epredia™

Ensure accurate, reproducible results with the Epredia™ p170/p-Glycoprotein/MDR Ab-2, Mouse Monoclonal Antibody.

$663.00 - $765.00

Specifications

Antigen p170/p-Glycoprotein/MDR Ab-2
Clone F4
Applications Immunofluorescence, Western Blot
Classification Monoclonal
Conjugate Unconjugated
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Products 4
Catalog Number Mfr. No. Concentration Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Concentration Quantity Price Quantity & Availability  
MS660P1
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Epredia
MS660P1
200μg/mL 500 μL
Each for $765.00
Only null left
Add to Cart
 
MS660P1ABX
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Epredia
MS660P1ABX
1mg/mL 100 μL
Each for $663.00
Only null left
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MS660P
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Epredia
MS660P
200μg/mL 1 mL N/A N/A N/A
MS660PABX
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Epredia
MS660PABX
1mg/mL 200 μL N/A N/A N/A
Description

Description

Multi-drug resistance(MDR) associated p-glycoprotein (p170) causes resistance to various drugs in a number of cancer patients. It exists in a soluble and membrane associated form. Soluble P-glycoprotein is detected in extracellular fluids of cancer patients, such as malignant ascites and serum. The Mr of soluble P-glycoprotein is the same as that of membrane bound P-glycoprotein.

Host Species: Mouse

Clone: F4

Isotype: IgG1

Species Reactivity: Human, Chinese Hamster. Does not react with mouse. Others not known.

Epitope: Extracellular amino terminal half. This epitope is resistant to formalin fixation and periodate oxidation and is different from those of other commonly known MAbs to p-glycoprotein, such as C219, JSB-1, and MRK16, which recognize an intracellular and extracellular epitope of p-glycoprotein, respectively.

Immunogen: Human and hamster drug-resistant viable cells followed by crude plasma membranes

Molecular Weight: 170kDa

Positive Control: Drug-resistant cells, Kidney or breast CA

Cellular Localization: Membrane

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence
  • Flow Cytometry (Fixed cells only)

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

p170/p-Glycoprotein/MDR Ab-2
Immunofluorescence, Western Blot
Unconjugated
Mouse
Cancer and Tumor Biology
Human and hamster drug-resistant viable cells followed by crude plasma membranes
Primary
F4
Monoclonal
Concentrated
RUO
Hamster, Human
IgG1
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