p53 Ab-5 Mouse Monoclonal Antibody, Epredia™

Achieve accurate, reproducible results with the Epredia™ p53 Ab-5, Mouse Monoclonal Antibody.

Catalog Number	Mfr. No.	Form	Conjugate	Quantity
MS186B1	Epredia MS186B1	Concentrated	Biotin	500 μL
MS186B	Epredia MS186B	Concentrated	Biotin	1 mL
MS186P1	Epredia MS186P1	Concentrated	Unconjugated	500 μL
MS186P	Epredia MS186P	Concentrated	Unconjugated	1 mL
MS186RQ	Epredia MS186RQ	Ready-to-Use	Unconjugated	12 mL
MS186B0	Epredia MS186B0	Concentrated	Biotin	100 μL
MS186P1ABX	Epredia MS186P1ABX	Concentrated	Unconjugated	100 μL
MS186PABX	Epredia MS186PABX	Concentrated	Unconjugated	200 μL

Description

p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to mdm2, SV40 T antigen and human papilloma virus E6 protein p53 senses DNA damage and possibly facilitating repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.

Host Species: Mouse

Clone: DO-7

Isotype: IgG2b/κ

Species Reactivity: Human, Monkey, Cow. Others not known.

Epitope: aa 37-45

Immunogen: Recombinant human wild-type p53 protein expressed in E. coli

Molecular Weight: 53kDa

Positive Control: SKBR-3 or MDA-231 cells, Colon CA

Cellular Localization: Nuclear

Recommended for:

• Immunohistochemistry (Formalin/paraffin)
• Western Blotting
• Immunofluorescence
• Immunoprecipitation (Denatured verified)
• Flow Cytometry

Specifications

• Antigen: p53 Ab-5
• Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Host Species: Mouse
• Research Discipline: Cancer and Tumor Biology
• Primary or Secondary: Primary

• Clone: DO-7
• Classification: Monoclonal
• Regulatory Status: IVD
• Immunogen: Recombinant human wild-type p53 protein expressed in E. coli