LAG3 Recombinant Rabbit Monoclonal Antibody (BLR028F), Bethyl Laboratories

Rabbit Recombit Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-157-2650	Bethyl Laboratories, Inc A700028T	10 μL
50-157-2649	Bethyl Laboratories, Inc A700028	100 μL

Description

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For ICC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections. For IHC, epitope retrieval with citrate buffer pH 6.0 is recommende

LAG-3 is a 70-kDa surface glycoprotein belonging to the Ig superfamily with homology to CD4. LAG-3 binds to MHC class II with higher affinity than CD4 and is thought to be involved in the negative regulation of T cell activation and homeostatic proliferation. Surface expression of LAG-3 has been reported on activated T cells (including regulatory T cells) and NK cells. CD8+ T cells usually express LAG-3 at significantly higher levels than CD4+ T cells. Coexpression of LAG-3 and CD49b has been proposed to identify human and mouse Type 1 regulatory T cells (Tr1 cells).

Specifications

• Antigen: LAG3
• Applications: Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human
• Gene Accession No.: P18627
• Gene ID (Entrez): 3902
• Immunogen: recombit protein representing the extracellular domain of human LAG3
• Primary or Secondary: Primary
• Content And Storage: 4° C
• Gene: LAG3

• Clone: BLR028F
• Classification: Recombinant Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: BBS with 0.09% sodium azide; pH 8.2
• Gene Alias: Lymphocyte-activation gene 3, CD223
• Gene Symbols: LAG3
• Isotype: IgG
• Purification Method: Antigen affinity chromatography
• Product Type: Antibody