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Lambda Light Chain Antibody (LAM03), Novus Biologicals™
SDP

Catalog No. NBP234235B Shop All R&D Systems Products
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0.1 mg
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Catalog No. Quantity
NBP234235B 0.2 mg
NBP234235F 0.02 mg
NBP234235A 0.1 mg
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Catalog No. NBP234235B Supplier Novus Biologicals Supplier No. NBP2342350.2MG

Description

Mouse Monoclonal Antibody

Lambda Light Chain Monoclonal antibody specifically detects Antigen in Human samples. It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blotting.

Specifications

Antigen Lambda Light Chain
Applications Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone LAM03
Conjugate Unconjugated
Dilution Western Blot 0.5-1.0ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml, Immunoprecipitation 0.5-1ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml, SDS-Page
Formulation PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene Accession No. P01701
Gene Alias IGLC, immunoglobulin lambda constant group
Gene Symbols IGL
Host Species Mouse
Immunogen Purified human lambda light chain
Molecular Weight of Antigen 22.5 kDa
Purification Method Protein A purified
Quantity 0.2 mg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3536
Test Specificity This MAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
Target Species Human
Content And Storage Store at 4C.
Form Purified
Isotype IgG1 κ
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