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Tocris Bioscience™ LM11A 31 dihydrochloride
Nonpeptide p75NTR ligand; neuroprotective
$169.36 - $700.64
Specifications
| Purity | 95% |
|---|---|
| Molecular Formula | (2 S,3 S)-2-Amino-3-methyl-N-[2-(4-morpholinyl)ethyl]pentanamide dihydrochloride |
| CAS | 1243259-19-9 |
| Content And Storage | Desiccate at RT |
| Product Type | LM11A 31 dihydrochloride |
Description
Nonpeptide p75NTR ligand; blocks p75-mediated cell death and also increases proliferation and survival of hippocampal neural progenitors. Exhibits no effect on nerve growth factor (NGF) binding to TrkA. Prevents and reverses atrophy of cholinergic neurites, as well as reversing Alzheimer's Disease (AD) pathologies in mid- to late-stage AD mice models. Shown to promote functional recovery in a mouse model of spinal cord injury. Orally available and brain penetrant.Specifications
| 95% | |
| 1243259-19-9 | |
| LM11A 31 dihydrochloride | |
| LM11A 31 dihydrochloride |
| (2 S,3 S)-2-Amino-3-methyl-N-[2-(4-morpholinyl)ethyl]pentanamide dihydrochloride | |
| Desiccate at RT | |
| M.W. (Observed): 316.27 |
For Research Use Only
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