Macrophage and Histiocytoma Marker Antibody (D11), Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP2452780.02MG

Catalog No. NBP24527800

Description

Ensure accurate, reproducible results in Immunohistochemistry (Paraffin)

Macrophage and Histiocytoma Marker Monoclonal specifically detects Macrophage and Histiocytoma Marker in Human, Mouse (Negative), Porcine (Negative), Rat (Negative) samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

• Antigen: Macrophage and Histiocytoma Marker
• Classification: Monoclonal
• Concentration: 0.2mg/mL
• Dilution: Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml
• Host Species: Mouse
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Test Specificity: In Western blotting, it detects an antigen of 125kDa in human liver and 135kDa in tumors of histiocytic origin. Comparative study of this MAb and a standard CD68 MAb showed that their antigens are different. Its antigen in all macrophage types studied is located on the plasma membrane and within cytoplasmic structures including lysosomes. This MAb shows a restricted reactivity to cells of the monocyte/macrophage system. It specifically reacts with blood monocytes and stains resident macrophages in a wide variety of human tissues. This MAb does not stain antigen-presenting cells, e.g., Langerhans cells. Reportedly, its reactivity is restricted to histiocytes and macrophages.
• Content And Storage: Store at 4C.
• Isotype: IgG1 κ

• Applications: Immunohistochemistry (Paraffin)
• Clone: D11
• Conjugate: Unconjugated
• Formulation: 10mM PBS with 0.05% Sodium Azide
• Immunogen: Membrane preparation from human hepatocytes
• Quantity: 0.02 mg
• Primary or Secondary: Primary
• Target Species: Human, Mouse (Negative), Porcine (Negative), Rat (Negative)
• Form: Purified

For Research Use Only