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Macrophage and Histiocytoma Marker Antibody (D11), Novus Biologicals™
SDP

Catalog No. p-5540782 Shop All R&D Systems Products
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NBP24527800 0.02 mg
NBP24527801 0.1 mg
NBP24527802 0.2 mg
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Catalog No. NBP24527800 Supplier Novus Biologicals Supplier No. NBP2452780.02MG
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Description

Mouse Monoclonal Antibody

Ensure accurate, reproducible results in Immunohistochemistry (Paraffin)

Macrophage and Histiocytoma Marker Monoclonal specifically detects Macrophage and Histiocytoma Marker in Human, Mouse (Negative), Porcine (Negative), Rat (Negative) samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen Macrophage and Histiocytoma Marker
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone D11
Concentration 0.2mg/mL
Conjugate Unconjugated
Dilution Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml
Formulation 10mM PBS with 0.05% Sodium Azide
Host Species Mouse
Immunogen Membrane preparation from human hepatocytes
Purification Method Protein A or G purified
Quantity 0.02 mg
Regulatory Status RUO
Primary or Secondary Primary
Test Specificity In Western blotting, it detects an antigen of 125kDa in human liver and 135kDa in tumors of histiocytic origin. Comparative study of this MAb and a standard CD68 MAb showed that their antigens are different. Its antigen in all macrophage types studied is located on the plasma membrane and within cytoplasmic structures including lysosomes. This MAb shows a restricted reactivity to cells of the monocyte/macrophage system. It specifically reacts with blood monocytes and stains resident macrophages in a wide variety of human tissues. This MAb does not stain antigen-presenting cells, e.g., Langerhans cells. Reportedly, its reactivity is restricted to histiocytes and macrophages.
Target Species Human, Mouse (Negative), Porcine (Negative), Rat (Negative)
Content And Storage Store at 4C.
Form Purified
Isotype IgG1 κ
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