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MCAM/CD146 Antibody (OJ79c), Novus Biologicals™
SDP

Catalog No. p-7105543 Shop All R&D Systems Products
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0.1 mg
0.2 mg
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Catalog No. Quantity
NBP234275F 0.02 mg
NBP234275A 0.1 mg
NBP234275B 0.2 mg
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Catalog No. NBP234275F Supplier Novus Biologicals Supplier No. NBP2342750.02MG
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Description

Mouse Monoclonal Antibody

MCAM/CD146 Monoclonal specifically detects MCAM/CD146 in Human samples. It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence.

Specifications

Antigen MCAM/CD146
Applications Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Frozen)
Classification Monoclonal
Clone OJ79c
Conjugate Unconjugated
Dilution Western Blot 0.5-1.0ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1.0ug/ml, Immunoprecipitation 1-2ug/500ug protein, Immunohistochemistry-Frozen 0.5-1ug/ml
Formulation PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene Accession No. P43121
Gene Alias CD146, CD146 antigen, cell surface glycoprotein MUC18, Cell surface glycoprotein P1H12, melanoma adhesion molecule, melanoma cell adhesion moleculeS-endo 1 endothelial-associated antigen, Melanoma-associated antigen A32, Melanoma-associated antigen MUC18, MUC18Gicerin
Gene Symbols MCAM
Host Species Mouse
Immunogen Recombinant human MUC18 protein
Molecular Weight of Antigen 130 kDa
Purification Method Protein A purified
Quantity 0.02 mg
Regulatory Status RUO
Research Discipline Cancer, Mesenchymal Stem Cell Markers, Stem Cell Markers
Primary or Secondary Primary
Gene ID (Entrez) 4162
Test Specificity The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.
Target Species Human
Content And Storage Store at 4C.
Form Purified
Isotype IgG1 κ
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