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Mouse anti-Siglec-3/CD33, Clone: WM53, Azide Free, Novus Biologicals™

Mouse Monoclonal Antibody

$366.50

Specifications

Antigen Siglec-3/CD33
Clone WM53
Concentration 1.0 mg/mL
Immunogen Human AML cells
Gene Accession No. P20138
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
NBP23451101
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Novus Biologicals
NBP2345110.1 MG
0.1 mg
Each for $366.50
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NBP23451102
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Novus Biologicals
NBP2345110.2 MG
0.2 mg This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000. N/A
Description

Description

Siglec-3/CD33 Monoclonal antibody specifically detects Siglec-3/CD33 in Human samples. It is validated for Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Frozen, Functional, CyTOF-ready.
Specifications

Specifications

Siglec-3/CD33
1.0 mg/mL
P20138
10mM PBS - BSA free with No Preservative
Recognizes a 67kDa glycoprotein, which is identified as CD33 (HLDA IV; WS Code M-505). CD33 is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It belongs to the immuno-receptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies; these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface. CD33 is expressed on cells of myelomonocytic lineage, binds sialic acid residues in N- and O-glycans on cell surfaces, and is a therapeutic target for acute myeloid leukemia. CD33 is expressed on myeloid progenitors, monocytes, granulocytes, dendritic cells and mast cells. It is absent on platelets, lymphocytes, erythrocytes and hematopoietic stem cells.
Primary
Mouse
Unconjugated
Protein A purified
Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Frozen)
WM53
Human AML cells
945
Protein A purified
Monoclonal
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
IgG1 Kappa
Purified
RUO
SDS
Product Certifications

For Research Use Only

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