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MUC5AC Antibody (45M1), DyLight 350, Novus Biologicals™
SDP

Catalog No. NBP232732UV Shop All R&D Systems Products
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Catalog No. NBP232732UV Supplier Novus Biologicals Supplier No. NBP232732UV
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Description

Mouse Monoclonal Antibody

MUC5AC Monoclonal specifically detects MUC5AC in Human, Mouse, Rat, Porcine, Chicken, Feline, Mammal, Monkey, Rabbit, Bovine (Negative) samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Dot Blot, Flow (Intracellular).

Specifications

Antigen Mucin 5AC
Applications Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone 45M1
Conjugate DyLight 350
Dilution Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Formulation 50mM Sodium Borate with 0.05% Sodium Azide
Gene Alias gastric mucin, leB, lewis B blood group antigen, major airway glycoprotein, MUC5, mucin 5, subtypes A and C, tracheobronchial/gastric, mucin 5AC, oligomeric mucus/gel-forming, mucin 5AC, oligomeric mucus/gel-forming pseudogene, mucin-5 subtype AC, tracheobronchial, mucin-5AC, TBM, tracheobronchial mucin
Gene Symbols MUC5AC
Host Species Mouse
Immunogen M1 mucin preparation from the fluid of an ovarian mucinous cyst belonging to an O Le(a-b) patient
Purification Method Protein A or G purified
Quantity 0.1 mL
Research Discipline Cellular Markers, Extracellular Matrix, Infections (Virus Bacteria and Parasites), Signal Transduction
Primary or Secondary Primary
Gene ID (Entrez) 4586
Test Specificity This monoclonal antibody recognizes the peptide core of gastric mucin M1 (recently identified as Mucin 5AC).Its epitope is located in the C-terminal cysteine rich part of the peptide core of MUC5AC. Its epitope is destroyed by beta-mercaptoethanol but not by periodate treatment. This mucin is present in primary ovarian mucinous cancer but usually absent in colorectal adenocarcinoma, thus showing an expression pattern opposite to MUC2. Together with a panel of antibodies, Anti-MUC5AC may be useful for differential identification of primary mucinous ovarian tumors from colon adenocarcinoma metastatic to the ovary. MUC5AC antibodies may also be useful for identification of intestinal metaplasia as well as in the identification of pancreatic carcinoma and pre-cancerous changes vs. normal pancreas.
Target Species Human, Mouse, Rat, Pig, Chicken, Feline, Primate, Rabbit, Bovine (Negative)
Content And Storage Store at 4C in the dark.
Form Purified
Isotype IgG1 κ
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