Invitrogen™ Procollagen I N-Peptide Monoclonal Antibody (C6)

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
PIMA541662	Invitrogen™ MA541662	200 μL
PIMA543883	Invitrogen™ MA543883	20 μL

Description

Procollagen I N-Peptide Monoclonal Antibody for Western Blot, IHC (P)

Procollagen type I N-terminal propeptide (P1NP) is a specific marker of bone formation, reflecting the synthesis of type I collagen, which constitutes the major part of the bone matrix. P1NP is derived during the conversion of procollagen to collagen, produced by osteoblasts during bone formation. Its primary clinical application lies in the diagnosis and monitoring of metabolic bone diseases, particularly osteoporosis. In osteoporotic patients, P1NP levels can predict bone mineral density (BMD) responses to treatments like teriparatide and romosozumab. Low serum levels of P1NP are indicative of a high risk of BMD loss, providing a valuable tool for premenopausal women with systemic lupus erythematosus (SLE) and other conditions affecting bone health.

Specifications

• Antigen: Procollagen I N-Peptide
• Concentration: 1 mg/mL
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Host Species: Mouse
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300
• Gene Accession No.: P02452
• Gene ID (Entrez): 1277
• Immunogen: Recombinant protein Procollagen I N-Terminal Propeptide.
• Product Type: Antibody

• Clone: C6
• Content And Storage: -20°C
• Classification: Monoclonal
• Form: Liquid
• Isotype: IgG1 κ
• Target Species: Human
• Gene: COL1A1
• Gene Alias: P1NP; Procollagen I N
• Gene Symbols: COL1A1
• Primary or Secondary: Primary
• Purification Method: Protein A/G