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Thermo Scientific™ ProPac™ WCX-10 HPLC Columns
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Catalog No. dx054993
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Length (Metric):
50 mm
100 mm
150 mm
250 mm
Diameter (Metric):
2 mm
4 mm
9 mm
22 mm
Column Format:
Analytical Column
Column Set (3 Columns, 1 Lot)
Guard Column
Semi-Preparative Column
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Catalog No. Length (Metric) Diameter (Metric) Column Format
DX054993 250 mm 4 mm Analytical Column
DX063472 250 mm 2 mm Analytical Column
DX063474 250 mm 9 mm Semi-Preparative Column
08-876-6 250 mm 22 mm Analytical Column
DXSP5512 250 mm 4 mm Column Set (3 Columns, 1 Lot)
DXSP5829 100 mm 4 mm Analytical Column
DXSP6703 150 mm 4 mm Analytical Column
DX054994 50 mm 4 mm Guard Column
DX063480 50 mm 2 mm Guard Column
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Catalog No. DX054993 Supplier Thermo Scientific™ Supplier No. 054993
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Separate proteins and their variants using these weak cation-exchange columns with exceptionally high resolution.

Use Thermo Scientific™ ProPac™ WCX-10 LC Columns to provide exceptionally high resolution for separations of proteins and their variants. Based on stationary phases composed of 10μm nonporous polymeric beads, ProPac columns resolve isoforms that differ by a single charged residue. A thin, hydrophilic layer grafted to the particle core eliminates unwanted secondary interactions. The cation-exchange surface provides pH-based selectivity control and fast mass transfer for high-efficiency separation and moderate capacity.

Multiple Formats for Greater Flexibility
  • ProPac WCX-10 column is a weak cation-exchanger with a carboxylate functional group
  • Column sizes range from 2mm I.D., for analytical work, up to 22mm I.D. for semi-prep work
Superior Performance for Protein Analysis
  • Ideal for characterization and quality control assessment of MAbs and other proteins
  • Well-suited for characterization of related protein variants including deamidation and MAb lysine truncation variants
  • Unequaled high-resolution separations
  • Unmatched column-to-column and lot-to-lot reproducibility eliminates column variability as a concern in stability and QA/QC testing

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TRUSTED_SUSTAINABILITY

Specifications

Column Format Analytical Column
Diameter (Metric) 4 mm
Flow Rate 1 mL/min
Length (Metric) 250 mm
Max. Pressure 3000 psi (207 bar)
Mobile Phase Compatibility pH 2 to 12, 80% compatible with acetonitrile and acetone, compatible with nonionic and zwitterionic detergents, incompatible with cationic detergents
Particle Size 10 μm
pH 2 to 12
Pore Size Nonporous
Quantity Each
Temperature 60°C
Stationary Phase Carboxylate
Product Line ProPac
Packing Material Spherical, Nonporous Polymer
Column Type Ion Exchange
Phase Ion Exchange
Type Analytical Column
Technique Bio-LC
Green Features FSC
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