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PTH Antibody (PTH/911) - N-terminal, Novus Biologicals™
SDP

Catalog No. NBP24511102 Shop All R&D Systems Products
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NBP24511102 0.2 mg
NBP24511100 0.02 mg
NBP24511101 0.1 mg
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Catalog No. NBP24511102 Supplier Novus Biologicals Supplier No. NBP2451110.2MG

Description

Mouse Monoclonal Antibody

Ensure accurate, reproducible results in Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

PTH Monoclonal antibody specifically detects PTH in Human samples. It is validated for Flow Cytometry, Immunohistochemistry-Paraffin, Immunofluorescence.

Specifications

Antigen PTH
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
Classification Monoclonal
Clone PTH/911
Concentration 0.2mg/mL
Conjugate Unconjugated
Dilution Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml
Formulation 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias Parathormone, Parathyrin, parathyroid hormone, parathyroid hormone 1, PTH1
Gene Symbols PTH
Host Species Mouse
Immunogen A synthetic peptide from the N-terminal of human PTH polypeptide.
Molecular Weight of Antigen 9 kDa
Purification Method Protein A or G purified
Quantity 0.2 mg
Regulatory Status RUO
Research Discipline Apoptosis, Cancer
Primary or Secondary Primary
Gene ID (Entrez) 5741
Test Specificity Epitope of this MAb maps in the N-terminus of PTH, a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2+ levels by dissolving the salts in bone and preventing their renal excretion.It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH); also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.
Target Species Human
Content And Storage Store at 4C.
Form Purified
Isotype IgG2b κ
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