Rat anti-MHC Class II, Clone: M5/114.15.2, PE, Novus Biologicals™

Rat Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
NBP14376705	Novus Biologicals NBP1437670.05MG	0.05 mg
NBP14376701	Novus Biologicals NBP1437670.1MG	0.1 mg
NBP14376702	Novus Biologicals NBP1437670.2MG	0.2 mg

Description

MHC class II (I-A/I-E) Monoclonal specifically detects MHC class II (I-A/I-E) in Human, Mouse samples. It is validated for Flow Cytometry.

Specifications

• Antigen: MHC Class II
• Concentration: 0.2 mg/mL
• Applications: Flow Cytometry
• Conjugate: PE
• Regulatory Status: RUO
• Target Species: Mouse
• Gene Alias: class II histocompatibility antigen, M alpha chain, D6S222E, DMA, HLA class II histocompatibility antigen, DM alpha chain, major histocompatibility complex, class II, DM alpha, MHC class II antigen DMA, Really interesting new gene 6 protein, RING6HLADM
• Gene Symbols: HLA-DMA
• Isotype: IgG2b κ
• Purification Method: Affinity Purified
• Test Specificity: The monoclonal antibody reacts with the mouse major histocompatibility complex class II, both I-A and I-E subregion-encoded glycoproteins (I-A b, I-A d, I-A q, I-E d, I-E k, not I-A f, I-A k, or I-A s). It detects a polymorphic determinant present on B cells, monocytes, macrophages, dendritic cells, and activated T lymphocytes from mice carrying the H-2 b, H-2 d, H-2 q, H-2 p, H-2 r and H-2 u but not from mice carrying the H-2 s or H-2 f haplotypes. The M5/114 mAb is reported to inhibit I-A-restricted T cell responses of the H-2 b, H-2 d, H-2 q, H-2 u but not H-2 f, H-2 k, or H-2 s haplotypes.

• Clone: M5/114.15.2
• Dilution: Flow Cytometry 1:10-1:1000
• Classification: Monoclonal
• Host Species: Rat
• Research Discipline: Adaptive Immunity, Immune System Diseases, Immunology, Major Histocompatibility Complexes, Transcription Factors and Regulators
• Formulation: Aqueous buffer, may contain carrier protein/stabilizer (proprietary) with 0.09% Sodium Azide
• Gene ID (Entrez): 3108
• Immunogen: The immunogen for this antibody was MHC Class II.
• Primary or Secondary: Primary
• Content And Storage: Store at 4C. Do not freeze.

For Research Use Only