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TfR (Transferrin R) Antibody (66IG10), DyLight 650, Novus Biologicals™
SDP

Catalog No. NBP234542C Shop All R&D Systems Products
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NBP234542C 0.1 mL
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Catalog No. NBP234542C Supplier Novus Biologicals Supplier No. NBP234542C
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Description

Mouse Monoclonal Antibody

TfR (Transferrin R) Monoclonal specifically detects TfR (Transferrin R) in Human samples. It is validated for Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence.

Specifications

Antigen TfR (Transferrin R)
Applications Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)
Classification Monoclonal
Clone 66IG10
Conjugate DyLight 650
Dilution Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen
Gene Alias CD71 antigen, CD71TRFR, p90, T9, TfR, TFR1, TR, transferrin receptor (p90, CD71), transferrin receptor protein 1, Trfr
Gene Symbols TFRC
Host Species Mouse
Immunogen Human thymocytes (T-cells)
Purification Method Protein A or G purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Cell Biology, Cellular Markers, Hematopoietic Stem Cell Markers, Immunology, Signal Transduction, Stem Cell Markers
Primary or Secondary Primary
Gene ID (Entrez) 7037
Test Specificity It recognizes a ∼90-95kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190kDa. This monoclonal antibody is highly specific to CD71 and shows no cross-reaction with other related proteins. Its epitope is localized in the extracellular domain of CD71. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.
Target Species Human
Content And Storage Store at 4C in the dark.
Form Purified
Isotype IgG1 κ
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For Research Use Only

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