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Thymidine Phosphorylase/PD-ECGF Ab-1 Mouse Monoclonal Antibody, Epredia™

Provide accurate, reproducible results with the Epredia™ Thymidine Phosphorylase/PD-ECGF Ab-1, Mouse Monoclonal Antibody.

Specifications

Antigen Thymidine Phosphorylase/PD-ECGF Ab-1
Clone P-GF.44C
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Conjugate Unconjugated
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Products 7
Catalog Number Mfr. No. Form Concentration Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Form Concentration Quantity Price Quantity & Availability  
MS499P0
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Epredia
MS499P0
Concentrated 200μg/mL 100 μL N/A N/A N/A
MS499P1
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Epredia
MS499P1
Concentrated 200μg/mL 500 μL N/A N/A N/A
MS499P
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Epredia
MS499P
Concentrated 200μg/mL 1 mL N/A N/A N/A
MS499P1ABX
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Epredia
MS499P1ABX
Concentrated 1mg/mL 100 μL N/A N/A N/A
MS499PABX
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Epredia
MS499PABX
Concentrated 1mg/mL 200 μL N/A N/A N/A
MS499R1
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Epredia
MS499R1
Prediluted 1 mL N/A N/A N/A
MS499R7
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Epredia
MS499R7
Prediluted 7 mL N/A N/A N/A
Description

Description

Platelet-derived endothelial growth factor (PD-ECGF), same as thymidine phosphorylase (TP) or gliostatin. In the presence of inorganic orthophosphate, it catalyses the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites.

Host Species: Mouse

Clone: P-GF.44C

Isotype: IgG1

Species Reactivity: Human, Mouse and Rat. Others not known.

Epitope: Not determined

Immunogen: Recombinant full-length human thymidine phosphorylase (TP/PD-ECGF) protein

Molecular Weight: 55kDa (reduced)

Positive Control: HUVEC cells, Breast CA

Cellular Localization: Cytoplasmic and nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting (Not verified)
  • Neutralizes Enzymatic Activity of TP/PD-ECGF (Not verified)

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

Thymidine Phosphorylase/PD-ECGF Ab-1
Immunohistochemistry (Paraffin)
Unconjugated
RUO
Human, Mouse, Rat
IgG1
P-GF.44C
Monoclonal
Mouse
Angiogenesis
Recombinant full length human thymidine phosphorylase (TP/PD-ECGF) protein
Primary
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