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TWIST Monoclonal Antibody, Active Motif™
Mouse Monoclonal Antibody
$132.55 - $397.65
Specifications
| Antigen | TWIST |
|---|---|
| Concentration | 1 mg/mL |
| Applications | Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot |
| Classification | Monoclonal |
| Conjugate | Unconjugated |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
50-199-3140
|
Active Motif
61098 |
10 μg |
Each for $132.55
|
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50-199-3139
|
Active Motif
61097 |
100 μg |
Each for $397.65
|
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Description
TWIST1 acts as a transcriptional regulator. It inhibits myogensis by sequestering E proteins, inhibiting trans-activation by MEF2, and inhibiting DNA-binding by MYOD1 through physical interaction. TWIST1 also represses proinflammatory cytokines such as TNFA and IL1B. TWIST also regulates cranial suture patterning and fusion and gene expression differentially depending on dimer composition. Mutations in the gene are implicated in Saethre-Chotzen syndrome, a disease characterized by coronal synostosis, brachycephaly, low front hairline, facial asymmetry, hypertelorism, broad halluces, and clinodactyly.Specifications
| TWIST | |
| Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot | |
| Unconjugated | |
| Mouse | |
| Human, Mouse | |
| P26687, Q15672 | |
| 22160, 7291 | |
| This TWIST antibody was raised against a recombinant protein corresponding to full-length mouse TWIST. | |
| Primary | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| TWIST1 |
| 1 mg/mL | |
| Monoclonal | |
| Liquid | |
| RUO | |
| 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8 | |
| AA960487; ACS3; B-HLH DNA binding protein; BHLHA38; BOS_4079; BPES2; BPES3; charlie chaplin; Class A basic helix-loop-helix protein 38; CRS; CRS1; CSO; H-twist; M-twist; p ACS3; Pde; pdt; Pluridigite; polydactyly EMS; SCS; Ska |
|
| TWIST1 | |
| IgG1 | |
| Protein G | |
| Antibody |
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