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VCAM-1/CD106 Antibody (B-K9), Alexa Fluor™ 594, Novus Biologicals™
SDP

Catalog No. NP247864A94 Shop All R&D Systems Products
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NP247864A94 0.1 mL
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Catalog No. NP247864A94 Supplier Novus Biologicals Supplier No. NBP247864AF594
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Description

Mouse Monoclonal Antibody

VCAM-1/CD106 Monoclonal specifically detects VCAM-1/CD106 in Human, Rat samples. It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunofluorescence.

Specifications

Antigen VCAM-1/CD106
Applications Flow Cytometry, Immunofluorescence
Classification Monoclonal
Clone B-K9
Conjugate Alexa Fluor 594
Dilution Flow Cytometry, Immunofluorescence
Formulation 50 mM sodium borate with 0.05% sodium azide
Gene Alias CD106, CD106 antigen, DKFZp779G2333, INCAM-100, L1CAM, MGC99561, vascular cell adhesion molecule 1, vascular cell adhesion protein 1, V-CAM 1, VCAM1, VCAM-1
Gene Symbols VCAM1
Host Species Mouse
Immunogen Activated human umbilical vein endothelial cells (HUVEC)
Quantity 0.1 mL
Primary or Secondary Primary
Gene ID (Entrez) 7412
Test Specificity Recognizes a protein of 110kDa, identified as CD106 (also known as vascular cell adhesion molecule-1 (VCAM-1) and INCAM-100). CD106 is a member of the Ig superfamily of adhesion molecules and is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on un-stimulated endothelial cells. It is also present on follicular and inter-follicular dendritic cells of lymph nodes, myoblasts, and some macrophages. CD106 serves as a ligand for leukocyte integrin (VLA-4 or CD49d/CD29) and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in various immunological and inflammatory responses. This monoclonal antibody inhibits the binding of leukocytes to VCAM-1 on stimulated endothelial cells.
Target Species Human, Rat
Content And Storage Store at 4°C in the dark.
Isotype IgG1 κ
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