Biochemical Reagents
![STA PHARMACEUTICAL US LLC Fmoc-L-Asp(tBu)-L-Ser[PSI(Me,Me)Pro]-OH | 25 g | CAS 955048-92-7 | MDL MFCD27957352](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502362048.PNG-250.jpg)
STA PHARMACEUTICAL US LLC Fmoc-L-Asp(tBu)-L-Ser[PSI(Me,Me)Pro]-OH | 25 g | CAS 955048-92-7 | MDL MFCD27957352
Fmoc-L-Asp(tBu)-L-Ser[PSI(Me,Me)Pro]-OH is a Amino Acid reagent (Subcategory: Pseudo AA) sold by WuXi TIDES. Offered in 25 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 955048-92-7
- MDL: MFCD27957352
- InChIKey: AUPKCQXNRAZESL-GOTSBHOMSA-N
- Molecular Weight: 538.597
- Molecular Formula: C29H34N2O8
- Purity: ≥95%
- Container Type: 125 mL HDPE
- Pack Size: 25 g
- Net Weight: 25 g
- Gross Weight: 54.3 g
- Commodity Code: 29349990
- Country Of Origin: China
- IUPAC: (S)-3-((S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-4-(tert-butoxy)-4-oxobutanoyl)-2,2-dimethyloxazolidine-4-carboxylic acid
- SMILES: CC(C)(OC(C[C@H](NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)C(N4[C@H](C(O)=O)COC4(C)C)=O)=O)C
STA PHARMACEUTICAL US LLC Fmoc-D-Asp-Obn | 50 g | CAS 1932027-25-2 | InChIKey CBZSVHFNEMONDZ-HSZRJFAPSA-N
Fmoc-D-Asp-Obn is a Amino Acid reagent (Subcategory: Asp) sold by WuXi TIDES. Offered in 50 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 1932027-25-2
- MDL: No data
- InChIKey: CBZSVHFNEMONDZ-HSZRJFAPSA-N
- Molecular Weight: 445.471
- Molecular Formula: C26H23NO6
- Purity: ≥95%
- Container Type: 250 mL HDPE
- Pack Size: 50 g
- Net Weight: 50 g
- Gross Weight: 89.8 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: (R)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-4-(benzyloxy)-4-oxobutanoic acid
- SMILES: OC(C[C@H](C(OCC1=CC=CC=C1)=O)NC(OCC2C3=CC=CC=C3C4=C2C=CC=C4)=O)=O
STA PHARMACEUTICAL US LLC Boc-L-Ser(Fmoc-L-Asp(OtBu))-OH | 50 g | CAS 944283-16-3 | MDL MFCD14560598
Boc-L-Ser(Fmoc-L-Asp(OtBu))-OH is a Amino Acid reagent (Subcategory: Pseudo AA) sold by WuXi TIDES. Offered in 50 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 944283-16-3
- MDL: MFCD14560598
- InChIKey: VUJFELZNXRRVHV-ZEQRLZLVSA-N
- Molecular Weight: 598.649
- Molecular Formula: C31H38N2O10
- Purity: ≥95%
- Container Type: 250 mL HDPE
- Pack Size: 50 g
- Net Weight: 50 g
- Gross Weight: 89.8 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: O-((S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-4-(tert-butoxy)-4-oxobutanoyl)-N-(tert-butoxycarbonyl)-L-serine
- SMILES: CC(C)(OC(C[C@@H](C(OC[C@@H](C(O)=O)NC(OC(C)(C)C)=O)=O)NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)=O)C
Medchemexpress LLC ASP-8731 | 2488255-42-9 | 98.4% | 395.41 | 1 ML
ASP-8731 is an orally active BACH1 inhibitor that activates antioxidant, anti-inflammatory, and globin gene pathways by relieving BACH1's inhibitory effect on NRF2-mediated gene transcription. It upregulates HMOX1, FTH1, and various globins (HGB, HBG, HBA), increasing fetal hemoglobin (HbF) and inducing F-cell production. It also reduces inflammatory responses, white blood cell counts, heme-induced glutathione depletion, and microcirculatory stasis, showing potential for inhibiting sickle cell disease and related hematological disorders.
- Orally active BACH1 inhibitor
- Activates antioxidant, anti-inflammatory, and globin gene pathways
- Increases fetal hemoglobin (HbF) levels
- Reduces inflammation and white blood cell counts
- Blocks heme-induced glutathione depletion and microcirculatory stasis
- Potential for sickle cell disease treatment
STA PHARMACEUTICAL US LLC Fmoc-L-Asp-OBzl | 1 g | CAS 86060-83-5 | MDL MFCD00198201
Fmoc-L-Asp-OBzl is a Amino Acid reagent (Subcategory: Asp) sold by WuXi TIDES. Offered in 1 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 86060-83-5
- MDL: MFCD00198201
- InChIKey: CBZSVHFNEMONDZ-QHCPKHFHSA-N
- Molecular Weight: 445.471
- Molecular Formula: C26H23NO6
- Purity: ≥95%
- Container Type: 15 mL HDPE
- Pack Size: 1 g
- Net Weight: 1 g
- Gross Weight: 7.8 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: (S)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-4-(benzyloxy)-4-oxobutanoic acid
- SMILES: O=C(OCC1=CC=CC=C1)[C@H](CC(O)=O)NC(OCC2C3=CC=CC=C3C4=CC=CC=C42)=O
STA PHARMACEUTICAL US LLC Boc-L-Thr(Fmoc-L-Asp(OtBu))-OH | 25 g | CAS 944283-33-4 | MDL MFCD18426605
Boc-L-Thr(Fmoc-L-Asp(OtBu))-OH is a Amino Acid reagent (Subcategory: Pseudo AA) sold by WuXi TIDES. Offered in 25 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 944283-33-4
- MDL: MFCD18426605
- InChIKey: PGYUAOMDCYWBFY-VAQLEPBLSA-N
- Molecular Weight: 612.676
- Molecular Formula: C32H40N2O10
- Purity: ≥95%
- Container Type: 125 mL HDPE
- Pack Size: 25 g
- Net Weight: 25 g
- Gross Weight: 54.3 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: O-((S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-4-(tert-butoxy)-4-oxobutanoyl)-N-(tert-butoxycarbonyl)-L-threonine
- SMILES: C[C@H]([C@@H](C(O)=O)NC(OC(C)(C)C)=O)OC([C@@H](NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)CC(OC(C)(C)C)=O)=O
Medchemexpress LLC L-aspartic acid β-hydroxamate | 1955-68-6 | MFCD00050389 | 98.0% | 148.12 g/mol | C4H8N2O4 | 5 MG
L-Aspartic acid β-hydroxamate is an aspartic acid derivative supplied as a white to off-white solid for laboratory research. The compound is well characterized (C4H8N2O4, 148.12 g/mol) and is provided at high purity for biochemical and pharmacological studies.
- High purity (98.0%) suitable for research applications.
- White to off-white solid for convenient handling.
- Molecular weight 148.12 g/mol and formula C4H8N2O4.
- Soluble in water (62.5 mg/mL with warming); limited solubility in DMSO.
- Store powder at -20°C for long-term stability; shorter stability in solution.
- Intended for research use only; not for human or veterinary use.
Medchemexpress LLC H-Asp-OMe | 17812-32-7 | 95.0% | 147.13 g·mol⁻¹ | C5H9NO4 | 10 G
H-Asp-OMe is the methyl ester derivative of aspartic acid provided as a white to off-white solid for research use. It serves as an amino acid derivative and building block in peptide synthesis and related chemical biology studies, with typical purity suitable for many laboratory applications.
- Methyl ester of aspartic acid useful as a building block in peptide synthesis.
- White to off-white solid, convenient for handling and weighing.
- 95.0% purity suitable for many research applications.
- Available in multiple pack sizes suitable for small- and mid-scale work.
- Powder storage stability: -20°C for 3 years or 4°C for 2 years.
- In solvent storage recommendation: -80°C for 6 months or -20°C for 1 month.
STA PHARMACEUTICAL US LLC Fmoc-L-Lys(Fmoc)-OPfp | 50 g | CAS 132990-14-8 | MDL MFCD00153377
Fmoc-L-Lys(Fmoc)-OPfp is a Amino Acid reagent (Subcategory: Lys) sold by WuXi TIDES. Offered in 50 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 132990-14-8
- MDL: MFCD00153377
- InChIKey: OBFVHZCPMVZYQG-XIFFEERXSA-N
- Molecular Weight: 756.726
- Molecular Formula: C42H33F5N2O6
- Purity: ≥95%
- Container Type: 250 mL HDPE
- Pack Size: 50 g
- Net Weight: 50 g
- Gross Weight: 89.8 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: perfluorophenyl N2,N6-bis(((9H-fluoren-9-yl)methoxy)carbonyl)-L-lysinate
- SMILES: O=C([C@H](CCCCNC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)NC(OCC4C5=CC=CC=C5C6=CC=CC=C64)=O)OC7=C(C(F)=C(C(F)=C7F)F)F
STA PHARMACEUTICAL US LLC Fmoc-D-Asp-OtBu | 25 g | CAS 134098-70-7 | MDL MFCD00237011
Fmoc-D-Asp-OtBu is a Amino Acid reagent (Subcategory: Asp) sold by WuXi TIDES. Offered in 25 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 134098-70-7
- MDL: MFCD00237011
- InChIKey: VZXQYACYLGRQJU-LJQANCHMSA-N
- Molecular Weight: 411.454
- Molecular Formula: C23H25NO6
- Purity: ≥95%
- Container Type: 125 mL HDPE
- Pack Size: 25 g
- Net Weight: 25 g
- Gross Weight: 54.3 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: (R)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-4-(tert-butoxy)-4-oxobutanoic acid
- SMILES: CC(OC([C@@H](CC(O)=O)NC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)=O)(C)C
Medchemexpress LLC Fmoc-asp-ome | 145038-52-4 | MFCD03701473 | 99.3% | 369.37 g/mol | C20H19NO6 | 500 G
Fmoc-Asp-OMe is the 9-fluorenylmethoxycarbonyl-protected methyl ester of aspartic acid, used as an Fmoc-protected amino acid building block in solid-phase peptide synthesis and organic synthesis applications.
- used as an Fmoc-protected aspartic acid building block for peptide synthesis
- chemical formula: C20H19NO6
- molecular weight: 369.37 g/mol
- purity typically 99.3%
- appearance: white to off-white solid
- solubility: soluble in DMSO (100 mg/mL) and formulatable for in vivo use with common co-solvents
STA PHARMACEUTICAL US LLC Fmoc-L-Asp-pNA | 100 g | CAS 185547-52-8 | MDL MFCD02179637
Fmoc-L-Asp-pNA is a Amino Acid reagent (Subcategory: Beta AA) sold by WuXi TIDES. Offered in 100 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 185547-52-8
- MDL: MFCD02179637
- InChIKey: WIGASSLCYMGNEA-QFIPXVFZSA-N
- Molecular Weight: 475.457
- Molecular Formula: C25H21N3O7
- Purity: ≥95%
- Container Type: 500 mL HDPE
- Pack Size: 100 g
- Net Weight: 100 g
- Gross Weight: 160.5 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: (S)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-4-((4-nitrophenyl)amino)-4-oxobutanoic acid
- SMILES: O=C(C[C@H](NC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)C(NC4=CC=C(C=C4)[N+]([O-])=O)=O)O
Medchemexpress LLC Asp-9521 | 1126084-37-4 | 98.0% | 330.42 | 50 MG
ASP-9521 is a potent, selective and orally available AKR1C3 inhibitor with an IC50 of 11 nM for human AKR1C3.
- IC50: 11 nM (human AKR1C3), 49 nM (monkey AKR1C3)
- Inhibits conversion of androstenedione (AD) into androstenediol and testosterone (T) by recombinant human or cynomolgus AKR1C3.
- Shows more than 100-fold selectivity for AKR1C3 over the isoform AKR1C2.
- Suppresses AD-dependent PSA production and cell proliferation in LNCaP-AKR1C3 cells.
- Single oral administration (3 mg/kg) inhibits AD-induced intratumoural T production in CWR22R xenografts, with the inhibitory effect maintained for 24 h.
- Rapidly eliminated from plasma after oral administration, while intratumoural concentration remained high.
- Bioavailability after oral administration (1 mg/kg) is 35% in rats, 78% in dogs, and 58% in monkeys.
Medchemexpress LLC ASP-4058 | 952565-91-2 | 99.54% | 442.31 | 100 MG
ASP-4058 is a next-generation, selective and oral bioactive agonist for Sphingosine 1-Phosphate receptors 1 and 5 (S1P1 and S1P5). It ameliorates rodent experimental autoimmune encephalomyelitis with a favorable safety profile. It is for research use only and not sold to patients.
- Next-generation, selective, and oral bioactive agonist for S1P1 and S1P5 receptors.
- Ameliorates rodent experimental autoimmune encephalomyelitis.
- Favorable safety profile.
- Reduces clinical score in a dose-dependent manner in EAE rats.
- Prevents decreases in body weight of EAE rats.
- Maintains clinical score at a relatively low level in EAE mice.
Cayman Chemical Ac-DEVD-pNA 10mg
A para-nitro aniline chromophore cleaved by caspases (Km = 18, 11, 32, 180, and 12 µM for caspases-1, -3, -4, -6, and -7, respectively); not cleaved by caspase-2; monitored colorimetrically at 405 nm