This monoclonal antibody is designed for the detection of endogenous levels of total CD54/ICAM-1 protein. It is produced by immunizing animals with SDS-denatured, formalin-fixed cultured COLO-38 human melanoma cells. CD54/ICAM-1 is a cell surface glycoprotein belonging to the immunoglobulin superfamily that plays a vital role in leukocyte trafficking, host defense, and cell signaling pathways, including the activation of Src family kinases.
- Host species: Mouse
- Isotype: IgG1
- Validated applications: Immunofluorescence (immunocytochemistry) and flow cytometry (fixed/permeabilized and live)
- Species reactivity: Human
- Storage conditions: -20°C
- Formulation: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 μg/ml BSA, 50% glycerol and less than 0.02% sodium azide