Also available in 1 mg, 10 mg, 25 mg, 50 mg and bulk. Please contact Fisher for quotes. Lipopolysaccharides, Escherichiacoli (E. coli O111B4) are derived from Escherichia coli O111B4 and are a unique component of the cell wall of Gram-negative bacteria. They are composed of three regions lipid A, oligosaccharide core, and O-specific polysaccharide (O-antigen). Lipopolysaccharides, Escherichiacoli help maintain the integrity of the cell outer membrane and protect bacteria from bile salts and lipid antibiotics.