Carbohydrates
Sugar alcohols
(4,071)
Glycosyl compounds
(2,988)
Monosaccharides
(1,643)
Sugar acids and derivatives
(976)
Oligosaccharides
(484)
Aminosaccharides
(278)
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Cayman Chemical D-Glucose-13C6 500mg
An internal standard for the quantification of D-(+)-glucose by GC- or LC-MS
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Medchemexpress LLC SN-38 glucuronide | 121080-63-5 | 99.5% | 568.53 | 1 MG
SN-38 glucuronide, also known as SN-38G, is an inactive metabolite of the anticancer molecule Irinotecan. It has known toxic effects on the gastrointestinal tract. Irinotecan is a topoisomerase I inhibitor used in research for colon and rectal cancer. SN-38 glucuronide can be reactivated by gut microbial β-glucuronidase enzymes, which remove the glucuronic acid moiety, thus increasing its toxic effects on the intestine.
- Inactive metabolite of Irinotecan.
- Has toxic effects on the gastrointestinal tract.
- Can be reactivated by gut microbial β-glucuronidase enzymes.
- Relevant in the study of colon and rectal cancer.
- Cells metabolizing SN38 to SN38-G show increased resistance to extracellular SN38.
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Cell Signaling Technology SLAMF6/CD352 (E3H1E) XP(R) Rabbit mAb 20 ul
SLAMF6/CD352 (E3H1E) XP(R) Rabbit mAb 20 ul
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