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Various organic compounds consisting of carbon, hydrogen, and oxygen atoms that are found in foods and living tissues; typically broken down to release energy; includes sugars, sugar alcohols, sugar acids and derivatives, glycosyl compounds, and more.
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PILR- is part of a family of paired receptors that play a critical regulatory role in the immune system PILR- functions as an activating receptor and is thought to participate in cell signaling by binding to ITAM-bearing adapter molecules suggesting its role in transmitting immune response signals PILR-beta Protein Human (HEK293 His) is the recombinant human-derived PILR-beta protein expressed by HEK293 with N-His labeled tag
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Sodium carboxymethyl cellulose (Viscosity 800-1200 mPa s) is the sodium salt of cellulose arboxymethyl and frequently used as viscous agent paste and barrier agent
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SIRP-beta (Sirpb CD172b) is a member of the signal-regulatory-protein (SIRP) family and also belongs to the immunoglobulin superfamily SIRP family members are receptor-type transmembrane glycoproteins Sirpb was found to interact with TYROBP/DAP12 a transmembrane adaptor protein bearing immunoreceptor tyrosine-based activation motifs resulting in the tyrosine phosphorylation of DAP12 and the subsequent recruitment of Syk to the Sirpb-DAP12 complex Sirpb is also implicated as a positive regulator of hematopoietic cells SIRP beta Protein Mouse (HEK293 His) is the recombinant mouse-derived SIRP beta protein expressed by HEK293 with C-His labeled tag
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Integrin V beta 5 proteins specifically the -V (ITGAV) subunit are multifunctional receptors for ligands such as vitronectin and fibronectin and recognize RGD sequences ITGAV ITGB3 binds fractalkine and acts as a coreceptor in CX3CR1-dependent signaling Integrin alpha V beta 5 Protein Human (HEK293 His-Avi) is a recombinant protein dimer complex containing human-derived Integrin alpha V beta 5 protein expressed by HEK293 with C-Avi C-His labeled tag Integrin alpha V beta 5 Protein Human (HEK293 His-Avi) has molecular weight of 85-160 kDa
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Diethylstilbestrol-d8 is the deuterium-labeled analogue of diethylstilbestrol supplied as a high-purity powder for research and analytical use. It is intended as a stable isotope internal standard for LC-MS, pharmacokinetic studies, and quantitative assays where mass differentiation from the parent compound is required.
High isotopic purity suitable for mass spectrometry internal standard.
Purity 99.7% as supplied.
Molecular formula C18H12D8O2 and molecular weight 276.40.
Recommended solvent: DMSO, 50 mg/mL with ultrasonic and warming.
Storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
Supplied in small research pack sizes appropriate for analytical workflows.
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Nonyl β-D-glucopyranoside is a nonionic alkyl glycoside surfactant used as a mild detergent and for studies of lipid monolayers and membrane interactions. It is supplied as a solid and as a 10 mM solution in DMSO, and is suitable for biochemical and membrane protein applications.
Nonionic surfactant for lipid monolayer and membrane interaction studies.
Mild detergent suitable for membrane protein isolation and biochemical assays.
High purity (99.79%) for reproducible experimental results.
Available as solid in multiple sizes and as a 10 mM solution in DMSO.
Solid appearance simplifies storage and handling for lab use.
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Nonyl β-D-glucopyranoside is a non-ionic alkyl-glucoside surfactant used in biochemical and surface-chemistry applications. It is commonly used to study interactions with lipid monolayers, to solubilize hydrophobic biomolecules, and to support chiral separations of certain acids and amino acid derivatives.
Non-ionic surfactant suitable for membrane and lipid monolayer studies.
Aids solubilization of membrane proteins and hydrophobic compounds.
Supports chiral separations of certain herbicides and amino acid derivatives.
High listed purity (≈99.8%) for reproducible results.
Molecular weight 306.40 and formula C15H30O6.
Available in solid and solution formats for flexible use.
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Avenanthramide D is a phenolic acid found in oat (Avena sativa) that is used in biochemical and inflammation research. Supplied as a powder for in vitro assays and compound screening.
Phenolic acid researched for anti-inflammatory activity.
High purity suitable for biochemical assays.
Soluble in DMSO; ultrasonic assistance may be required.
Store protected from light at 4°C; in solution keep at -80°C for long-term storage.
Available in small research quantities, such as 5 mg, for assay development.
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IL-18 is a pleiotropic proinflammatory cytokine that is involved in induction of inflammatory mediators regulation of the cytotoxic activity of NK cells and T cells and differentiation and activation of both Th1 and Th2 cells IL-18 signals through its specific cell surface receptor IL-18R which comprises two subunits IL-18R and IL-18R beta IL-18 forms a signalling complex with the IL-18 receptor (R ) and (R ) chains at the plasma membrane which induces multiple inflammatory cytokines[2] IL-18R complex recruits the IL-1R- activating kinase and TNF- associated factor 6 which phosphorylates nuclear factor k - inducing kinase with subsequent activation of NF- k [3] IL-18R betaknockdown inhibits IL-18 driven tumor cell metastasis in C57/BL6 mice[4] IL-18RAP Protein Rhesus Macaque (HEK293 His) is a recombinant protein with a His label that consists of 357 amino acids (M1-R356) and is produced by HEK293 cells
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