Lipids and Lipid Derivatives
Medchemexpress LLC CBP-501 (acetate) | 1929.06 (free base) | 1 MG
CBP-501 acetate is a cell-permeable calmodulin-binding peptide and a G2-abrogating drug candidate. It inhibits the activity of multiple Ser216-specific kinases, including MAPKAP-K2, C-Tak1, CHK1, and CHK2. It is used for various types of cancer and enhances the cytotoxicity of CDDP and Bleomycin against cancer cells both in vitro and in vivo.
- Inhibits MAPKAP-K2 with an IC50 of 0.9 μM
- Inhibits C-Tak1 with an IC50 of 1.4 μM
- Inhibits Chk1 with an IC50 of 3.4 μM
- Inhibits Chk2 with an IC50 of 6.5 μM
- Stable for 2 years at -80°C as powder
- Stable for 1 year at -20°C as powder
- Stable for 6 months at -80°C in solvent
- Stable for 1 month at -20°C in solvent
- Enhances cytotoxicity of CDDP and Bleomycin
Medchemexpress LLC Resomelagon acetate | 1809420-72-1 | 99.75% | 358.35 | 100 MG
Resomelagon (AP1189) acetate is a potent, orally active melanocortin receptor (MR) agonist, specific for MC1 and MC3. It induces ERK1/2 phosphorylation and Ca2+ mobilization. Resomelagon acetate also exhibits anti-inflammatory activity and can be used for obesity and chronic inflammation research.
- Potent, orally active melanocortin receptor (MR) agonist about MC1 and MC3.
- Induces ERK1/2 phosphorylation and Ca2+ mobilization.
- Possesses anti-inflammatory activity.
- Applicable for obesity and chronic inflammation research.
Medchemexpress LLC Talfirastide acetate | 2855063-75-9 | 99.8% | 959.06 | C43H66N12O13 | 10MM 1ML
Talfirastide acetate is the acetate salt of the endogenous heptapeptide angiotensin-(1-7), used in research on the renin-angiotensin system and studies of cardiovascular, anti-inflammatory, and anti-fibrotic pathways. It is provided as a 10 mM solution (1 mL) or as a powder for reconstitution; sequence is Asp-Arg-Val-Tyr-Ile-His-Pro (DRVYIHP).
- Heptapeptide angiotensin-(1-7) acetate (sequence DRVYIHP).
- Supplied as 10 mM, 1 mL solution; powder available for reconstitution.
- Molecular weight 959.06; chemical formula C43H66N12O13.
- Purity reported as 99.8%.
- Storage: powder sealed at -80°C (2 years) or -20°C (1 year); in solvent -80°C (6 months) or -20°C (1 month).
- Intended for research use only.
Medchemexpress LLC Geranyl diphosphate 1mg | 116057-55-7 | 1 MG
Geranyl diphosphate triammonium is the triammonium salt of geranyl pyrophosphate, an isoprenoid intermediate used in terpene and sterol biosynthesis. Supplied as a high-purity reagent for research applications, it is suitable for enzymatic and biochemical studies.
- High purity suitable for biochemical assays.
- Available in small milligram pack sizes for research use.
- Water-soluble triammonium form for aqueous assay compatibility.
- Used as a substrate or intermediate in terpene biosynthesis studies.
Abcam Octyl-beta-D-thioglucopyranoside, APG surfactant
MW 308.44 Da, Purity >98%. APG surfactant. Reagent for the solubilisation and isolation of membranes.
Medchemexpress LLC TAT-CBD3A6K acetate | 1505463-57-9 | 99.8% | 3249.83 (free base) | 10 MG
TAT-CBD3A6K acetate is a modified TAT-CBD3 peptide that reduces T- and R-type voltage-dependent calcium currents in dorsal root ganglion (DRG) neurons. It also exhibits anti-nociceptive effects in a model of AIDS-induced peripheral neuropathy by preventing CRMP-2-mediated enhancement of T- and R-type calcium channel function.
- Reduces T- and R-type voltage-dependent calcium currents
- Exhibits anti-nociceptive effects in AIDS-induced peripheral neuropathy models
- Prevents CRMP-2-mediated enhancement of T- and R-type calcium channel function
- Modified TAT-CBD3 peptide
Medchemexpress LLC BMP-4 acetate | 99.3% | 1308.52 | 10 MG
BMP-4 acetate is a penetrating heparin-binding peptide with anti-inflammatory and anti-chondrogenic functions. It regulates the iNOS-IFN-IL6 signaling pathway to inhibit the expression of inflammatory proteins such as iNOS, COX2, IFN, and IL6, effectively suppressing inflammation and alleviating various arthritis symptoms in murine chondrocytes and macrophages.
- Penetrating heparin-binding peptide
- Anti-inflammatory and anti-chondrogenic functions
- Regulates iNOS-IFN-IL6 signaling pathway
- Inhibits expression of inflammatory proteins
- Suppresses inflammation and alleviates arthritis symptoms
- Targets IL-6 and COX-2
- Appearance: White to off-white crystal
- Soluble in H2O and DMSO at 100 mg/mL (requires sonication)
Medchemexpress LLC TAT-CBD3A6K acetate | 99.8% | 3249.83 (free base) | 1 MG
TAT-CBD3A6K acetate is a modified TAT-CBD3 peptide that reduces T- and R-type voltage-dependent calcium currents in dorsal root ganglion (DRG) neurons. It shows anti-nociceptive effects in a model of AIDS-induced peripheral neuropathy by preventing CRMP-2-mediated enhancement of T- and R-type calcium channel function.
- Peptides and derivatives
- Inhibitors and substrates
- Neurological applications
- Eye or ear disease research
- Inhibits calcium channels
- Used in AIDS research
- Anti-nociceptive effects
- Peripheral neuropathy studies
- DRG studies
Medchemexpress LLC Vapreotide acetate | 849479-74-9 | 98.2% | 1191.42 | 50 MG
Vapreotide acetate, also known as RC-160 acetate, is a neurokinin-1 (NK1) receptor antagonist. It inhibits Substance P (SP)-triggered intracellular calcium increases and NF-κB activation, making it suitable for various research applications in cell signaling and disease models.
- Neurokinin-1 (NK1) receptor antagonist with an IC50 of 330 nM
- Inhibits Substance P (SP)-induced IL-8 and MCP-1 production
- Demonstrates activity against HIV-1 infection in human MDM in vitro
- Effective in decreasing collateral circulation blood flow in cirrhosis in vivo
- Reduces tumor volumes in prostate-cancer xenografts in nude mice
Medchemexpress LLC Prt062607 (acetate) | 1370261-98-5 | C21H27N9O3 | 50 MG
PRT062607 acetate is a chemical compound suitable for laboratory use and the manufacture of substances. This product is stable under recommended storage conditions and is not classified as a hazardous substance or mixture. It is provided in solid form and is intended for research use only.
- Solid appearance
- Stable under recommended storage conditions
- Not classified as a hazardous substance or mixture
- Intended for research use only
- Recommended storage at 4°C, sealed, away from moisture
Medchemexpress LLC Vapreotide acetate | 849479-74-9 | 98.2% | 1191.42 | 10 MG
Vapreotide acetate is a neurokinin-1 (NK1) receptor antagonist with an IC50 of 330 nM. It is intended for research use only.
- Attenuates Substance P (SP)-triggered intracellular calcium increases and NF-κB activation.
- Inhibits SP-induced IL-8 and MCP-1 production.
- Inhibits HIV-1 infection of human MDM in vitro.
- Inhibits GH-, PRL, and/or alpha-subunit release by human GH-secreting pituitary adenoma cells.
- Exhibits affinities for SSTR2, -3, and -5.
- Reduces tumor volumes and weights in androgen-independent prostate cancer xenografts.
- Decreases collateral circulation blood flow in cirrhosis and attenuates its development.
Medchemexpress LLC Lysipressin acetate | 83968-49-4 | 99.8% | 1116.27 | 2 MG
Lysipressin (Lysine vasopressin) acetate is an antidiuretic hormone found in pigs and some marsupial families. It induces contraction of the rabbit urinary bladder smooth muscle and activates adenylate-cyclase. This product is suitable for laboratory use and research.
- Induces contraction of rabbit urinary bladder smooth muscle
- Activates adenylate-cyclase
- White to off-white solid appearance
- High purity of 99.8%
Medchemexpress LLC JMV 449 acetate | 141863-45-8 | 99.7% | 807.03 | 10 MG
JMV 449 acetate is a potent neurotensin receptor agonist. It shows an IC50 of 0.15 nM for inhibition of 125I-neurotensin binding to neonatal mouse brain and an EC50 of 1.9 nM in contracting the guinea-pig ileum. It also has highly potent and long-lasting hypothermic and analgesic effects in the mouse.
- Potent neurotensin receptor agonist
- IC50 of 0.15 nM for inhibition of 125I-neurotensin binding to neonatal mouse brain
- EC50 of 1.9 nM in contracting the guinea-pig ileum
- Highly potent and long-lasting hypothermic and analgesic effects in the mouse