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Estrone (E1) is a natural estrogenic hormone and the main representative of endogenous estrogens. It is produced by several tissues, particularly adipose tissue, through the aromatization of androstenedione in fat cells.
Purity of 99.96%
Molecular weight of 270.37
Chemical formula C18H22O2
Appears as a solid, white to off-white
Initial source from microorganisms or as an endogenous metabolite
Available as a 10 mM, 1 mL solution in DMSO
Soluble in DMSO (25 mg/mL or 92.47 mM)
Insoluble in water
For research use only
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A primary, naturally-occurring estrogen; serum concentrations in premenopausal women fluctuate according to the menstrual cycle; becomes the most predominant estrogen in postmenopausal women; binding affinities to ERα and ERβ are ~60% and ~37% relative to estradiol
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Estrone (E1) is a natural estrogenic hormone. It is the main representative of the endogenous estrogens and is produced by several tissues, especially adipose tissue. Estrone is the result of the aromatization of androstenedione that occurs in fat cells. It is the main endogenous estrogen in postmenopausal women.
Natural estrogenic hormone
Main endogenous estrogen in postmenopausal women
Solid, white to off-white appearance
Soluble in DMSO (25 mg/mL)
Insoluble in water (< 0.1 mg/mL)
Molecular formula C18H22O2
Molecular weight 270.37
Targets estrogen receptor/ERR
Acts as an endogenous metabolite
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A primary, naturally-occurring estrogen; serum concentrations in premenopausal women fluctuate according to the menstrual cycle; becomes the most predominant estrogen in postmenopausal women; binding affinities to ERα and ERβ are ~60% and ~37% relative to estradiol
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Estrone (Standard) is the analytical standard of Estrone, a natural estrogenic hormone (E1) produced by various tissues, particularly adipose tissue. It is intended for research and analytical applications, resulting from the aromatization of androstenedione in fat cells.
Used as a reference standard assay
Utilized in qualitative, quantitative, and methodological research experiments
Commonly used in HPLC, GC, and MS applications
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Estrone sulfate potassium (1240-04-6) is a small-molecule modulator targeting kinase activities implicated in estrogen signaling pathways It is designed to regulate estrogen-mediated biological processes by modulating specific kinase activities thereby influencing cellular responses related to steroid signaling Estrone sulfate potassium exerts its biological activity primarily through modulation of kinase pathways associated with estrogen signaling Laboratory studies indicate that estrone sulfate potassium can influence cellular responses via targeted kinase inhibition pathways Based on these pharmacological properties estrone sulfate potassium holds research potential in elucidating pathological mechanisms and identifying therapeutic targets related to endocrine disorders
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Estrone (53-16-7) is a naturally occurring estrogen that modulates estrogen receptor-mediated signaling pathways It is primarily synthesized in ovarian and adipose tissues and participates in the regulation of estrogen-dependent cellular and physiological processes Estrone exerts its biological activity primarily through binding and activating estrogen receptors Experimental model activity type and key metric (IC50/EC50) are not specified Based on these pharmacological properties estrone holds research potential in studies of estrogen receptor activation reproductive endocrinology menopausal hormone transitions and estrogen-dependent signaling pathways and diseases
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Alpha-Estradiol ( -Estradiol 17 alpha-Estradiol Alfatradiol Epiestradiol Epiestrol Alora 17 -E2) a natural non-feminizing stereoisomer a hormonally almost inactive isomer of physiological 17 beta-estradiol (17 -E2) is a weak inhibitor of estrogen
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Estradiol valerate is a synthetic estrogen widely used in combination with other steroid hormones in hormone replacement therapy agents. It is for research use only and not sold to patients. It is also identified as a reproductive toxicant and estrogenic chemical in both male and female fish.
Molecular weight: 356.50
Formula: C23H32O3
Appearance: Solid, white to off-white
Shipping: Room temperature in continental US
Storage: Powder at -20°C for 3 years, 4°C for 2 years; in solvent at -80°C for 2 years, -20°C for 1 year
Solubility in DMSO: ≥ 50 mg/mL (140.25 mM)
Solubility in ethanol: 12.5 mg/mL (35.06 mM)
Insoluble in H2O
Target: Estrogen Receptor/ERR
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