Lipids and Lipid Derivatives
Cayman Chemical Palmitoleic Acid ethyl ester
Ethyl palmitoleate is a more lipophilic form of the free acid. It is one of the fatty acid ethyl esters that increase cytosolic Ca2+ concentration leading to pancreatic acinar cell injury due to excessive consumption of ethanol. Ethyl palmitoleate (10-100 µM) in addition to 850 mM ethanol resulted in sustained, concentration-dependent increases in Ca2+ that caused cell death.{14121} This fatty acid ethyl ester is also a potential biomarker for fetal exposure to alcohol.{14123}
Indofine Chemical 5-HYDROXYISOVANILLIC ACID, Rare Organics & Biochemicals, 4319-02-2, >95% by HPLC, 100 mg
5-HYDROXYISOVANILLIC ACID, Rare Organics & Biochemicals, 4319-02-2, >95% by HPLC, 100 mg
Medchemexpress LLC Nω-Hydroxy-nor-l-arginine acetate | 1140844-63-8 | 99.5% | 296.28 | 10 MM * 1 ML
nor-NOHA acetate is a selective and reversible Arginase inhibitor. It induces Apoptosis in ARG2-expressing cells under hypoxia and exhibits anti-leukemic activity. Additionally, nor-NOHA acetate improves liver ischemia-reperfusion injury and can be utilized in studies related to tuberculosis, endothelial dysfunction, immunosuppression, and metabolism.
- Selective and reversible arginase inhibitor.
- Induces apoptosis in ARG2-expressing cells under hypoxia.
- Exhibits anti-leukemic activity.
- Improves liver ischemia-reperfusion injury.
- Can be used in studies of tuberculosis, endothelial dysfunction, immunosuppression, and metabolism.
Medchemexpress LLC C20 Ceramide (N-Arachidoyl-D-sphingosine) | 7344-02-7 | 99.1% | 594.01 | 25 MG
C20 Ceramide (N-Arachidoyl-D-sphingosine) is a natural 20:0 ceramide and a N-acylsphingosine in which the ceramide N-acyl group is specified as eicosanoyl. C20 Ceramide acts as a key signal molecule mediating biological processes. It is for research use only and not sold to patients.
- Natural 20:0 ceramide
- N-acylsphingosine with eicosanoyl N-acyl group
- Acts as a key signal molecule
- Mediates cell growth, differentiation, senescence, and apoptosis
- For research use only
Medchemexpress LLC Farnesyl pyrophosphate ammonium | 116057-57-9 | 95.4% | 433.42 | 10 MG
Farnesyl pyrophosphate ammonium | 116057-57-9 | 95.4% | 433.42 | 10 MG
Sigma Aldrich Fine Chemicals Biosciences Carvacrol >=98%, FCC, FG | 499-75-2 | MFCD00002236 | 5KG
Carvacrol >=98%, FCC, FG | Purity: >=98% | Mol Wt: 150.22 | 499-75-2 | MFCD00002236 | 5KG
Medchemexpress LLC Vapreotide acetate | 849479-74-9 | >98.16% | 1191.42 | 25 MG
Vapreotide acetate is a neurokinin-1 (NK1) receptor antagonist, characterized by an IC50 of 330 nM. It attenuates Substance P (SP)-triggered intracellular calcium increases and NF-κB activation, while inhibiting SP-induced IL-8 and MCP-1 production. It also inhibits HIV-1 infection and significantly reduces GH-, PRL, and/or alpha-subunit release from pituitary adenoma cells. The compound exhibits moderate-to-high affinities for SSTR2, -3, and -5.
- Neurokinin-1 (NK1) receptor antagonist.
- Attenuates SP-triggered calcium increases, NF-κB activation.
- Inhibits SP-induced IL-8 and MCP-1 production.
- Inhibits HIV-1 infection; reduces GH, PRL, and alpha-subunit release.
- Moderate-to-high affinities for SSTR2, -3, and -5.
- Can inhibit androgen-independent prostate cancer growth and decrease collateral circulation in cirrhotic rats.
Medchemexpress LLC 9-cis-Retinol acetate | 29584-22-3 | 85.0% | 328.49 | 10 MG
9-cis-Retinol acetate is a retinal derivative, also known as 9-cis-Vitamin A acetate or Zuretinol acetate. It is provided as a white to off-white solid and is intended for research use only, not for use with patients.
- Molecular weight: 328.49
- Formula: C22H32O2
- Purity: 85.0%
- Storage for powder: -20°C for 3 years, 4°C for 2 years
- Storage in solvent: -80°C for 6 months, -20°C for 1 month
Cayman Chemical PhytnIc AcId-d3 10mg
An internal standard for the quantification of phytanic acid by GC- or LC-MS
Medchemexpress LLC Delta-Tocopherol | 119-13-1 | 98.0% | 402.65 | 1 ML
Delta-Tocopherol is an isomer of Vitamin E. It is for research use only.
- Inhibits cell growth and induces apoptosis in human prostate cancer LNCaP cells (in vitro).
- Inhibits DHT-induced androgen receptor activation and its downstream target PSA in CWR-22Rv1/AR cells (in vitro).
- Decreases estrogen-induced cyclin D1 and c-Myc levels in MCF-7 cells and MDA-MB-231 cells (in vitro).
- Inhibits the development of prostate adenocarcinoma in Ptenp-/- mice (in vivo).
- Inhibits tumor growth in an MCF-7 xenograft model (in vivo).
- Appearance: Liquid (density: 0.9932 g/cm³).
- Color: Light yellow to brown.
- Initial source: Endogenous metabolite.
- Structure classification: Phenols.
Selleck Chemical LLC Betulinic acid S3603-100mg
Betulinic acid (ALS-357 Lupatic acid Betulic acid) a pentacyclic triterpenoid from Syzigium claviflorum is a inhibitor of HIV-1 with EC50 of 1 4 M It s reported that Betulinic acid acts as a new inhibitor of NF- B Phase 1/2
Medchemexpress LLC (±)-Abscisic acid | 14375-45-2 | 5 MG
(±)-Abscisic acid is an orally active plant hormone that is also present in animals. It contributes to the regulation of glycemia in mammals. For research use only, not for sale to patients.
Apexbio Technology LLC LXR-623 875787-07-8 10mg
LXR-623 (CAS 875787-07-8) is a small-molecule partial agonist targeting liver X receptors LXR- and LXR- It selectively activates LXR- and LXR- modulating cholesterol homeostasis by regulating gene expression involved in cholesterol transport LXR-623 exerts its biological activity primarily through induction of cholesterol transporters such as ABCA1 and ABCG1 enhancing cholesterol efflux and reverse cholesterol transport In animal models oral administration of LXR-623 increases expression of ABCA1 and ABCG1 in peripheral blood cells and intestinal ABCG5/ABCG8 in mouse atherosclerosis models with reported IC50 values of 24 nM for LXR- and 179 nM for LXR- Based on these pharmacological properties LXR-623 holds research potential in atherosclerosis and Alzheimer s disease
Apexbio Technology LLC Loganin 18524-94-2 20mg
Loganin (CAS 18524-94-2) is an iridoid glucoside that modulates key inflammatory and oxidative pathways Studies indicate that Loganin inhibits the enzymatic activity of cyclooxygenase-1 (Cox-1) and suppresses the production of tumor necrosis factor-alpha (TNF- ) implicating interference with pro-inflammatory signaling Additionally Loganin demonstrates marked free-radical-scavenging capacity and exerts inhibitory effects on melanogenesis These properties support the use of Loganin in research focused on inflammation oxidative stress and pigmentary disorders