Lipids and Lipid Derivatives
Abcam (-)-Epigallocatechin gallate, antio x idant flavonoid, 100MG
MW 458.38 g/mol, Purity >97%. Potent antioxidant flavonoid. Displays anticancer, antitumour activity and induces apoptosis. Modulates numerous cell signalling pathways, such as inhibiting NF-κB, MAPK and COX-2 pathways. Also shows anti-inflammatory, antibacterial and antiviral activities (EC₅₀ = ~22 μM for inhibition of influenza virus).
The product is subject to the following: Abcam Restricted Use Statement
Apexbio Technology LLC DEGARELIX-ACETATE-5MG
Degarelix acetate (CAS No 934016-19-0) is a gonadotropin-releasing hormone (GnRH) antagonist used in biomedical research primarily for its role in androgen deprivation therapy Originating from synthetic peptides it functions by binding to GnRH receptors in the anterior pituitary gland effectively decreasing the release of luteinizing hormone and subsequently reducing testosterone production Its in vitro activity typically ranges from the nanomolar to low micromolar concentration Degarelix acetate is commonly applied in cell models and animal studies to investigate prostate cancer treatment and it is also used in drug screening for hormonal therapies Experimental concentrations typically depend on the specific research design offering flexibility in application across various studies
TARGETMOL CHEMICALS INC 7-Epi 10-desacetyl paclitaxel
7-Epi 10-desacetyl paclitaxel (10-Deacetyl-7-epipaclitaxel) shows IC50 values of 0.085 nM, against HeLa cells. Purity 98.05%
Medchemexpress LLC Docetaxel (standard) | 114977-28-5 | 99.9% | C43H53NO14 | 5 MG
Docetaxel (Standard) is the analytical standard of Docetaxel, intended for research and analytical applications. Docetaxel (RP-56976) acts as a microtubule depolymerization inhibitor with an IC50 of 0.2 μM. It attenuates the effects of bcl-2 and bcl-xL gene expression, arrests the cell cycle at G2/M, and induces cell apoptosis, demonstrating anti-cancer activity.
- Serves as a grade of analytical standard, providing a reference standard for assays
- Commonly utilized in qualitative, quantitative, and methodological research experiments, including techniques such as HPLC, GC, and MS
Medchemexpress LLC Paclitaxel-d5 | 1129540-33-5 | 1129540-33-5 | 99.9% | C47H46D5NO14 | 1 MG
Paclitaxel-d5 is a deuterium-labeled Paclitaxel, a natural antineoplastic agent that works by stabilizing tubulin polymerization. This product is strictly for research purposes and is not intended for patient use. Deuteration, the process of incorporating stable heavy isotopes into drug molecules, is primarily employed as a tracer for quantitation during the drug development process and can impact the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Stabilizes tubulin polymerization
- For research use only
Cayman Chemical Docetaxel-d9 500ug
An internal standard for the quantification of docetaxel by GC- or LC-MS