BMP-4 acetate is a penetrating heparin-binding peptide known for its anti-inflammatory and anti-chondrogenic properties. It operates by modulating the iNOS-IFN-IL6 signaling pathway, which leads to the suppression of inflammatory proteins such as iNOS, COX2, IFN, and IL6. This mechanism helps effectively reduce inflammation and alleviate various arthritis symptoms in both murine chondrocytes and macrophages.
- Penetrating heparin-binding peptide
- Exhibits anti-inflammatory functions
- Exhibits anti-chondrogenic functions
- Regulates the iNOS-IFN-IL6 signaling pathway
- Inhibits expression of inflammatory proteins (iNOS, COX2, IFN, IL6)
- Suppresses inflammation
- Alleviates arthritis symptoms in murine chondrocytes and macrophages