Nucleosides and Analogues
Medchemexpress LLC 2′-deoxyguanosine 5′-monophosphate-13C10,15N5 dilithium | MFCD00057076 | 99.8% | 373.98 g/mol | 13C10H12Li215N5O7P | 10 MG
2′-Deoxyguanosine 5′-monophosphate-13C10,15N5 dilithium is an isotopically labeled nucleotide provided as the dilithium salt. It is intended for use as a tracer and internal standard in quantitative analyses by NMR, GC-MS, and LC-MS, and is supplied in small, pre-weighed pack sizes suitable for preparing standard solutions.
Medchemexpress LLC 2'-Deoxyadenosine 5'-triphosphate disodium | 74299-50-6 | MFCD00080335 | 99.97% | 535.15 | 50 MG
2'-Deoxyadenosine 5'-triphosphate disodium is a nucleotide with important biological activities. It plays a key role in DNA synthesis and reverse transcription and is widely utilized in in vitro reactions in molecular biology research.
- Serves as a substrate for various polymerases
- Supports DNA synthesis
- Supports reverse transcription
- Suitable for in vitro reactions in molecular biology research
Medchemexpress LLC 2'-Deoxyguanosine 5'-monophosphate disodium hydrate | 146877-98-7 | 99.0% | C10H14N5O7.H2O.2Na | 50 MG
2'-Deoxyguanosine 5'-monophosphate (dGMP) disodium hydrate is an oxidizable target of pterin (PT) used to evaluate the photosensitizing properties of biopterins. Pterin induces a photosensitive reaction of dGMP under UV-A radiation, leading to DNA damage via two primary mechanisms: electron transfer (type I) and singlet molecular oxygen production (type II).
- Oxidizable target of pterin (PT).
- Evaluates photosensitizing properties of biopterins.
- Induces DNA damage under UV-A radiation.
- Functions through Type I (electron transfer) and Type II (singlet molecular oxygen production) mechanisms.
- Relevant to cell cycle and DNA damage studies.
- Involved in DNA/RNA synthesis research.
Medchemexpress LLC 6-Thio-2'-Deoxyguanosine | 789-61-7 | 99.7% | 283.31 | 10 MM * 1 ML
6-Thio-2'-Deoxyguanosine is a nucleoside analogue that can be incorporated into de novo-synthesized telomeres by telomerase.
- Nucleoside analogue
- Can be incorporated into de novo-synthesized telomeres by telomerase
- Rapid cell death for the vast majority of cancer cell lines tested with IC50s of between 0.7-2.9 μM (in vitro)
- Causes a decrease of the tumor growth rate in A549 lung cancer cell-based mouse xenograft studies, superior to that observed with 6-thioguanine treatment (in vivo)
- Increases telomere dysfunction in tumor cells in vivo
- Appearance: Solid
- Color: White to yellow
Medchemexpress LLC 3'-deoxyguanosine | 3608-58-0 | 97.0% | 267.25 | 1 ML
3'-deoxyguanosine | 3608-58-0 | 97.0% | 267.25 | 1 ML
Medchemexpress LLC 3′-Deoxyguanosine | 3608-58-0 | 97.0% | 267.25 | 50 MG
3′-Deoxyguanosine | 3608-58-0 | 97.0% | 267.25 | 50 MG
Cambridge Isotope Laboratories 2-Deoxyguanosine H2O (13C10 98% 15N5 96-98%) 5 mg
2-Deoxyguanosine H2O (13C10 98% 15N5 96-98%) 5 mg
Apexbio Technology LLC 2-Deoxyadenosine 958-09-8 500mg
2-Deoxyadenosine (CAS 958-09-8) is a synthetic purine nucleoside analog that functions as a demethylated nucleoside in biological systems Structurally similar to adenosine but lacking a hydroxyl group at the 2 position it selectively pairs with deoxythymidine during DNA synthesis 2-Deoxyadenosine influences regulatory pathways associated with DNA replication and repair serving as a molecular probe to study these processes It is extensively utilized in molecular biology and genomics for investigating DNA synthesis repair mechanisms and the dynamics of nucleic acid metabolism
Apexbio Technology LLC 6-O-Propynyl-2-deoxyguanosine 10mg
6-O-Propynyl-2-deoxyguanosine (CAS 1640051-47-3) is a modified nucleoside featuring an alkyne functional group at the 6-position of deoxyguanosine This structural modification enables its use in bioorthogonal click chemistry reactions facilitating site-specific labeling and conjugation in nucleic acid research The alkynyl group serves as a chemical handle for copper-catalyzed azide-alkyne cycloaddition allowing researchers to attach probes or other functional molecules 6-O-Propynyl-2-deoxyguanosine is utilized for studying DNA structure dynamics and for the development of modified oligonucleotides in biochemical and molecular biology assays
Medchemexpress LLC 6-Thio-2'-Deoxyguanosine | 789-61-7 | 99.7% | 283.31 | 50 MG
6-Thio-2'-Deoxyguanosine is a nucleoside analogue that can be incorporated into de novo-synthesized telomeres by telomerase. It causes rapid cell death for the majority of cancer cell lines tested with IC50s between 0.7-2.9 μM. In A549 lung cancer cell-based mouse xenograft studies, it decreases tumor growth rate and increases telomere dysfunction in tumor cells in vivo.
- Nucleoside analogue
- Incorporated into de novo-synthesized telomeres by telomerase
- Results in rapid cell death for the vast majority of cancer cell lines tested with IC50s of between 0.7-2.9 μM
- Causes a decrease of the tumor growth rate in A549 lung cancer cell-based mouse xenograft studies
- Increases telomere dysfunction in tumor cells in vivo
Medchemexpress LLC 7-deaza-2'-deoxyadenosine | 60129-59-1 | MFCD00672266 | >97.0% | 250.25 g/mol | C11H14N4O3 | 100 MG
7-deaza-2'-deoxyadenosine is a deoxynucleoside analog used as a biochemical reagent for research applications. It is used in studies of nucleic acid structure and function, and has been reported to inhibit DNA synthesis and related polymerase reactions.
- Oligodeoxynucleotide analog for biochemical research.
- Reported inhibitor of DNA synthesis and polymerase activity.
- Molecular formula: C11H14N4O3.
- Molecular weight: 250.25 g/mol.
- CAS number: 60129-59-1.
- Typical purity reported around 98%, minimum 97%.
- Available as a 100 mg quantity.
- For research use only; not for diagnostic or therapeutic use.
Medchemexpress LLC N6-Ethyladenosine | 14357-08-5 | 99.9% | 295.29 | 1 ML
N6-Ethyladenosine is an adenosine derivative that functions as an Adenosine receptor agonist, with Ki values of 4.9 nM and 4.7 nM for hA1AR and hA3AR, respectively. It exhibits higher selectivity for hA1AR and hA3AR compared to hA2AR (Ki, 8900±770 nM).
- Adenosine receptor agonist
- High selectivity for hA1AR and hA3AR over hA2AR
- Available in solid and solution forms
- Available for bulk inquiry
- Supported by research publications
TARGETMOL CHEMICALS INC 6-THIO-2-DEOXYGUANOSINE 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. 6-Thio-2'-Deoxyguanosine ((beta)-TGdR) is a nucleoside analog and telomerase substrate. purity: 99%
Bioworld 2'-Deoxyguanosine Monohydrate, 1 g
Nucleoside analogSpecifications:Ultra Pure GradeEm (252nm, phosphate buffer, pH 7.0): >13,300 Appearance: Powder.ChEBI : Not available.Crystal_Structure : Not available.InChI : Not available.InChIKey : Not available.Melting Point: >300 °C (dec.)(lit.)
Genscript Corporation CA15-3 AntibodyA5D8 mAb Mo
CA15-3 (Carcinoma antigen 15-3) is also known as MUC 1 antigen It is a membrane-anchored mucin-type glycoprotein present in malignant cells It is used as tumor marker to monitor breast cancer treatment and disease recurrence