Chromatography Standards
Apexbio Technology LLC Naftifine HCl 65473-14-5 50mg
Naftifine HCl (CAS 65473-14-5) is a small-molecule inhibitor targeting squalene 2 3-epoxidase It is designed to inhibit this key enzyme thereby disrupting the fungal sterol biosynthetic pathway Naftifine HCl exerts its biological activity primarily through inhibition of squalene 2 3-epoxidase leading to intracellular squalene accumulation and impairment of fungal membrane formation and integrity In in vitro studies Naftifine HCl demonstrates inhibitory activity with IC50 values generally ranging between 20 100 nM against common dermatophytes and fungal pathogens Based on these pharmacological properties Naftifine HCl holds research potential in studies of fungal infections and sterol synthesis inhibition mechanisms including conditions such as tinea pedis tinea corporis and tinea cruris
Sigma Aldrich Fine Chemicals Biosciences Fluconazole European Pharmacopoeia (EP) Reference Standard | 86386-73-4 | MFCD00274549 |
Fluconazole European Pharmacopoeia (EP) Reference Standard | Mol Wt: 306.27 | 86386-73-4 | MFCD00274549 |
Apexbio Technology LLC Diclazuril 101831-37-2 10mM (in 1mL DMSO)
Diclazuril is a benzeneacetonitrile derivative displaying anticoccidial activity by targeting developmental stages of parasites It inhibits both asexual replication and sexual gametogenesis phases of coccidia thus disrupting the parasite s proliferative and reproductive cycle In pharmacological studies Diclazuril exhibits inhibitory efficacy against various species of Eimeria parasites associated with coccidial infections in vitro and in vivo with reported IC50 values typically ranging from 0 01 to 2 M depending on parasite strain and assay conditions Additionally this compound serves as an investigative tool in experimental models studying acute Toxoplasma gondii infection pathogenesis parasite-host interactions and therapeutic intervention strategies as well as research on protozoal mechanisms in equine protozoal myeloencephalitis (EPM)
Cayman Chemical Chlorambucil-d8, Purity: ≥99% deuterated forms (d1-d8), CAS: 2748247-26-7, 1 mg
An internal standard for the quantification of chlorambucil by GC- or LC-MS
Medchemexpress LLC Benzoic acid, 2-methoxy-5-methyl-, methyl ester | 63113-79-1 | MFCD06411343 | 1g
Ilurodoline impurity 10 is an impurity of Ilurodoline
Sigma Aldrich Fine Chemicals Biosciences Desogestrel European Pharmacopoeia (EP) Reference Standard | 54024-22-5 | MFCD00869346 |
Desogestrel European Pharmacopoeia (EP) Reference Standard | Mol Wt: 310.47 | 54024-22-5 | MFCD00869346 |
Sigma Aldrich Fine Chemicals Biosciences Irbesartan | 138402-11-6 | MFCD00864464 | 10 mg
Irbesartan | Purity: ≥98% | Mol Wt: 428.53 | 138402-11-6 | MFCD00864464 | 10 mg
Apexbio Technology LLC Losartan Potassium (DuP 753) 124750-99-8 10mM (in 1mL DMSO)
Losartan Potassium (DuP 753 CAS 124750-99-8) is a small molecule antagonist selective toward angiotensin AT receptors By competitively blocking AT receptors it inhibits angiotensin II-mediated vasoconstriction demonstrated by antagonism of contractile responses in isolated rabbit aortic and jugular vein tissues (pA 8 27) As an orally bioavailable agent losartan potassium is frequently utilized in cardiovascular research notably in studies investigating hypertension and associated mechanisms of angiotensin II signaling
Medchemexpress LLC Ibrutinib methoxy impurity | 2031255-26-0 | MFCD34184521 | 10mg
Ibrutinib Impurity 14 is an impurity of Ibrutinib (HY-10997)
Selleck Chemical LLC Hypromellose S4444-1g
Hypromellose (Hydroxypropyl Methyl Cellulose HPMC Celacol HPM 5000) is a commonly employed cellulose ether used in the fabrication of hydrophilic matrices Hypromellose provides the release of a drug in a controlled manner effectively increasing the duration of release of a drug to prolong its therapeutic effect
Selleck Chemical LLC Xylazine HCl S2516-1g
Xylazine(BAY 1470 hydrochloride) is an 2-Adrenergic receptor agonist used as a sedative and muscle relaxant
Cayman Chemical Racecadotril, Purity: ≥98%, CAS: 81110-73-8, 500 mg
A prodrug form of thiorphan; reduces or prevents castor oil-induced diarrhea without delaying intestinal transit in rats at 80 or 100 mg/kg, respectively; decreases duration of diarrhea and increases body weight gain in a neonatal gnotobiotic pig model of human rotavirus-induced diarrhea
Apexbio Technology LLC Indapamide 26807-65-8 10mM (in 1mL DMSO)
Indapamide (CAS 26807-65-8) is a sulphonamide-derived diuretic structurally distinct from thiazides It functions by inhibiting sodium reabsorption primarily at the distal convoluted tubules of the nephron resulting in increased excretion of sodium and water This action reduces plasma volume and peripheral vascular resistance contributing to its antihypertensive effects Indapamide is also studied for its utility in models of decompensated cardiac failure due to its natriuretic and vasodilatory properties making it relevant for research into cardiovascular disease and fluid balance regulation