Cabozantinib (Standard) is the analytical standard of Cabozantinib, intended for research and analytical applications. It is a potent and orally active inhibitor of VEGFR2 and MET, with IC50 values of 0.035 nM and 1.3 nM, respectively. This compound also demonstrates strong inhibition of KIT, RET, AXL, TIE2, and FLT3. Cabozantinib exhibits antiangiogenic activity and disrupts tumor vasculature, promoting tumor and endothelial cell apoptosis.
- Serves as a reference standard for assays
- Commonly used in qualitative, quantitative, and methodological research experiments
- Suitable for techniques such as HPLC, GC, and MS
- Potent and orally active inhibitor of VEGFR2 and MET
- Strongly inhibits KIT, RET, AXL, TIE2, and FLT3
- Exhibits antiangiogenic activity
- Disrupts tumor vasculature
- Promotes tumor and endothelial cell apoptosis