5,7,4'-Trimethoxyflavone (MTF) is a compound isolated from the medicinal plant *Kaempferia parviflora*. It acts as a CFTR activator and demonstrates diverse biological activities, including inducing apoptosis and exhibiting antitumor properties. This compound can also help prevent skin aging and oxidative stress.
- CFTR activator with an EC50 of 64 μM
- Induces apoptosis in SNU-16 cells
- Increases proteolytic activation of caspase-3
- Degrades ADP-ribose polymerase (PARP) protein
- Exhibits antitumor activity
- Helps prevent skin aging and oxidative stress
- Inhibits cell proliferation and TNF-α induced ROS