Organometallic Compounds
![1,2-Bis[(dimethylamino)dimethylsilyl]ethane 93.0+%, TCI America™](https://assets.fishersci.com/TFS-Assets/CCG/Chemical-Structures/chemical-structure-cas-91166-50-6.jpg-250.jpg)
1,2-Bis[(dimethylamino)dimethylsilyl]ethane 93.0+%, TCI America™
CAS: 91166-50-6 Molecular Formula: C10H28N2Si2 Molecular Weight (g/mol): 232.52 MDL Number: MFCD00010649 InChI Key: MRAAXSSHMOFDJR-UHFFFAOYSA-N Synonym: 1,1′C-Ethylenebis(N,N,1,1-tetramethylsilanamine) PubChem CID: 4187062 IUPAC Name: 2,3,3,6,6,7-hexamethyl-2,7-diaza-3,6-disilaoctane SMILES: CN(C)[Si](C)(C)CC[Si](C)(C)N(C)C
eMolecules 1-(3-Bromopropoxy)-4-nitrobenzene | 13094-50-3 | MFCD00596643 | 1g
Combi-Blocks | 1-(3-Bromopropoxy)-4-nitrobenzene | 1g | 232301224 | AN-1194 | 95.000 | 13094-50-3 | MFCD00596643 | 260.087 | C9H10BrNO3
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Medchemexpress LLC 1,11-Bis-maleimidotetraethyleneglycol | 86099-06-1 | 98.0% | 50 MG
BM-PEG3 is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). PROTACs are molecules that leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins. This compound has a molecular weight of 352.34 and a chemical formula of C16H20N2O7, appearing as a white to light yellow solid. It is soluble in DMSO, with recommendations for proper storage and handling for both powder and solvent forms.
- It is a polyethylene glycol-based linker.
- It is used in the synthesis of proteolysis-targeting chimeras.
- It aids in the degradation of target proteins.
- It has a high purity of 98.0%.
- It is available as a white to light yellow solid.
- It can be dissolved in DMSO for in vitro experiments.
- It can be formulated for in vivo studies using specific co-solvents like DMSO and corn oil.
Medchemexpress LLC Acetoacetic acid | 541-50-4 | 95.0% | 102.09 | 1 MG
Acetoacetic acid is an oxidative stress inducer. It affects the antioxidant enzyme system and lipoprotein metabolism by decreasing mRNA expression and activity of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px), and increasing malondialdehyde (MDA) content. It also inhibits very low-density lipoprotein (VLDL) assembly, leading to triglyceride (TG) accumulation in hepatocytes, making it useful for studying metabolic diseases.
- Oxidative stress inducer
- Impacts antioxidant enzyme system
- Affects lipoprotein metabolism
- Decreases SOD, CAT, and GSH-Px activity and mRNA expression
- Increases malondialdehyde (MDA) content
- Inhibits VLDL assembly
- Leads to triglyceride (TG) accumulation in hepatocytes
- Useful for studying metabolic diseases
Medchemexpress LLC 3-Methyl-2-cyclopenten-1-one | 2758-18-1 | 99.1% | 96.13 | 50 G
3-Methyl-2-cyclopenten-1-one is an endogenous metabolite commonly utilized in scientific research. This high-purity chemical compound is suitable for various laboratory applications.
- Available in multiple quantities to suit diverse research requirements.
- Features high purity for reliable experimental results.
- Identified by a unique CAS number for easy reference and regulatory compliance.
Medchemexpress LLC Methotrexate hydrate | 133073-73-1 | 99.6% | C20H22N8O5.XH2O | 50 G
Methotrexate hydrate is a substance that affects cell growth and division. It is commonly used to fight certain diseases, especially cancer and autoimmune diseases. It works by inhibiting the process by which cells synthesize DNA. It is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
- Affects cell growth and division
- Used to fight cancer and autoimmune diseases
- Inhibits the process of DNA synthesis
- Biochemical reagent for life science research
Medchemexpress LLC Dbco-peg3-acid | 2754384-59-1 | 98.35% | 508.56 | 50 MG
DBCO-PEG3-acid is a non-cleavable 3 unit PEG ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs). It features a DBCO group, which facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
- Non-cleavable 3 unit PEG ADC linker.
- Used in the synthesis of antibody-drug conjugates (ADCs).
- Contains a DBCO group.
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with azide groups.
![eMolecules Medchem Express / TXNIP-IN-1 / 5mg / 536983907 / HY-115688 / / 1268955-50-5 / [null] / 248.238 / C12H12N2O4](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502476360.JPG-250.jpg)
eMolecules Medchem Express / TXNIP-IN-1 / 5mg / 536983907 / HY-115688 / / 1268955-50-5 / [null] / 248.238 / C12H12N2O4
Medchem Express / TXNIP-IN-1 / 5mg / 536983907 / HY-115688 / / 1268955-50-5 / [null] / 248.238 / C12H12N2O4
Medchemexpress LLC Butanoic acid, 3-oxo-, sodium salt (1:1) | 623-58-5 | 98.0% | 124.07 | 50 MG
Acetoacetic acid sodium is an oxidative stress inducer that affects the antioxidant enzyme system and lipoprotein metabolism. It can be used to study metabolic diseases. The sodium salt form of the compound is prone to thermal instability.
- Induces oxidative stress by decreasing mRNA expression and activity of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px)
- Increases MDA content
- Inhibits very low density lipoprotein (VLDL) assembly
- Downregulates apolipoprotein ApoB100, ApoE, and low density lipoprotein receptor (LDLR)
- Leads to triglyceride (TG) accumulation in hepatocytes
Medchemexpress LLC S-1-Propenyl-L-cysteine | 52438-09-2 | 99.9% | 161.22 | 50 MG
S-1-Propenyl-L-cysteine is a stereoisomer of S-allyl-l-cysteine, extracted from garlic. It exhibits immunomodulatory effects and reduces blood pressure in a hypertensive animal model. It also shows antioxidative efficacy through a NO-dependent BACH1 signaling pathway. This compound is orally active.
- Exhibits immunomodulatory effects
- Reduces blood pressure in a hypertensive animal model
- Shows antioxidative efficacy through a NO-dependent BACH1 signaling pathway
- Is orally active
- NO-dependently upregulates levels of HMOX1, causing downregulation and degradation of BACH1 in the nucleus
- Inhibits lipopolysaccharides (LPS)-induced TLR4 signaling pathway by inducing MyD88 degradation
- Reduces systolic blood pressure (SBP) and alters histidine metabolism in spontaneously hypertensive rats, exerting antihypertensive effects via the central histamine H3 receptor
Medchemexpress LLC Tri(Amino-PEG3-amide)-amine | 2523025-40-1 | 98.0% | C33H69N7O12 | 50 MG
Tri(Amino-PEG3-amide)-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- For research use only.
Medchemexpress LLC EGGGG-PEG8-amide-bis(deoxyglucitol) | 2842855-38-1 | 98.9% | C49H91N9O28 | 50 MG
EGGGG-PEG8-amide-bis(deoxyglucitol) is a cleavable ADC linker used for research purposes. It is a solid-liquid mixture, white to off-white in color, with a molecular weight of 1254.29.
- Cleavable ADC linker
- Solid-liquid mixture
- White to off-white color
- For research use only
Medchemexpress LLC (S)-S007-1558 (GPVI antagonist 1) | 1327156-14-8 | 99.8% | C19H19N3O4S | 50 MG
(S)-S007-1558 is a potent glycoprotein VI (GPVI) platelet receptor antagonist primarily used for research purposes. This compound effectively modulates platelet activity.
- Inhibits collagen-induced platelet aggregation (IC50 of 25.3 μM)
- Solid appearance, white to off-white color
- Molecular weight of 385.44
- Ships at room temperature (continental US)
- Powder storage: -20°C for 3 years, 4°C for 2 years
- In-solvent storage: -80°C for 6 months, -20°C for 1 month
- Soluble in DMSO at concentrations ≥ 50 mg/mL
Medchemexpress LLC Trimethyl[3-(trimethoxysilyl)propyl]ammonium (chloride) | 35141-36-7 | MFCD00007085 | 50% | C9H24ClNO3Si | 1 G
Trimethyl[3-(trimethoxysilyl)propyl]ammonium (chloride) (50% in methanol) is a biochemical reagent suitable for life science related research. This organic compound is supplied as a liquid solution.
- Used as a biochemical reagent
- Suitable for life science related research
- Liquid solution with colorless to light yellow appearance
- Molecular weight 257.83
Medchemexpress LLC PI3K/Akt/CREB activator 1 (compound AE-18) | 2708177-73-3 | C19H15F4NO3 | 50 MG
PI3K/Akt/CREB activator 1 (compound AE-18) is a potent, orally active activator that promotes neuronal proliferation, induces differentiation of Neuro-2a cells, and accelerates axon-dendrite polarization of primary hippocampal neurons. It achieves this by upregulating brain-derived neurotrophic factor via the PI3K/Akt/CREB pathway and is used in vascular dementia (VaD) research.
- Promotes neuronal proliferation and differentiation
- Accelerates axon-dendrite polarization of primary hippocampal neurons
- Upregulates brain-derived neurotrophic factor (BDNF)
- Improves cerebral blood flow recovery in models of chronic cerebral hypoperfusion (CCH)
- Mitigates impairment of learning and memory in CCH models
- Alleviates CCH-induced pathological injury in the hippocampus