Solvents
Cayman Chemical Flunxn-d3 1mg
An internal standard for the quantification of flunixin by GC- or LC-MS
Medchemexpress LLC Imipramine-d6 | 65100-45-0 | 500 UG
Imipramine-d6 is a deuterium-labeled Imipramine hydrochloride. Imipramine is an orally active tertiary amine tricyclic antidepressant, which acts as a Fascin1 inhibitor with antitumor activities and inhibits serotonin transporter with an IC50 value of 32 nM. It stimulates U-87MG glioma cells autophagy and induces HL-60 cell apoptosis, exhibiting neuroprotective and immunomodulatory effects.
- Used as a tracer for quantitation during drug development.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- May affect the pharmacokinetic and metabolic profiles of drugs due to deuteration.
- Fascin1 inhibitor with antitumor activities.
- Inhibits serotonin transporter (IC50 value of 32 nM).
- Stimulates U-87MG glioma cells autophagy.
- Induces HL-60 cell apoptosis.
- Shows neuroprotective effects.
- Exhibits immunomodulatory effects.
Medchemexpress LLC Tryptamine-d4 hydrochloride | 340257-60-5 | 99.53% | 1 MG
Tryptamine-d4 (hydrochloride) is the deuterium labeled Tryptamine hydrochloride. Tryptamine hydrochloride, a monoamine alkaloid, similar to other trace amines, is believed to play a role as a neuromodulator or neurotransmitter.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process.
- Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC 2-naphthol-d7 | 78832-54-9 | MFCD01074243 | 95.0% | 151.22 | C10HD7O | 25mg
2-Naphthol-d7 is the deuterium labeled 2-Naphthol[1] 2-Naphthol is a metabolite of naphthalene catalyzed by cytochrome P450 (CYP) isozymes (CYP 1A1 CYP 1A2 CYP 2A1 CYP 2E1 and CYP 2F2)[2]
Medchemexpress LLC 1,3-dihydroxyacetone | 96-26-4 | MFCD00004670 | 99.5% | 90.08 | C3H6O3 | 500mg
1 3-Dihydroxyacetone (DHA) the main active ingredient in sunless tanning skin-care preparations and an important precursor for the synthesis of various fine chemicals is produced on an industrial scale by microbial fermentation of glycerol (HY-B1659) in Gluconobacter oxydans 1 3-Dihydroxyacetone is also used for synthesis of new biodegradable polymers by combining with lactic acid (HY-B2227)[1][2]
Medchemexpress LLC Ciprofloxacin-d8 (hydrochloride) | 1216659-54-9 | 98.8% | 2.5 MG
Ciprofloxacin-d8 (hydrochloride) is the deuterium labeled Ciprofloxacin. Ciprofloxacin (Bay-09867) hydrochloride is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Cayman Chemical L-AlnIn-d3 50mg
An internal standard for the quantification of L-alanine by GC- or LC-MS
eMolecules 109-99-9 | Tetrahydrofuran ACS | Oakwood Chemicals | MFCD00005356 | 72.107 | C4H8O | 99.000 | C1CCOC1 | 1l | 480133467
Tetrahydrofuran ACS | Oakwood Chemicals | 109-99-9 | MFCD00005356 | 72.107 | C4H8O | 99.000 | C1CCOC1 | 1l | 480133467
Medchemexpress LLC 2-Butanone, 4-(4-hydroxyphenyl)- | 5471-51-2 | 164.20 | 10 G
2-Butanone, 4-(4-hydroxyphenyl)- | 5471-51-2 | 164.20 | 10 G
Medchemexpress LLC Dimethyl sulfoxide | 67-68-5 | MFCD00002089 | 100.0% | 78.13 g/mol | C2H6OS | 10mL
Dimethyl sulfoxide (DMSO) meets analytical specification of Ch P is an aprotic solvent that dissolves polar and non-polar compounds including water-insoluble therapeutic and toxic agents Dimethyl sulfoxide (DMSO) has a strong affinity for water and can rapidly penetrate or enhance the penetration of other substances into biological membranes Dimethyl sulfoxide also has potential free radical scavenging and anticholinesterase effects and may affect coagulation activity Dimethyl sulfoxide also induces histamine release from mast cells but is thought to have low systemic toxicity Dimethyl sulfoxide also exhibits antifreeze and antibacterial properties[1][2][3] br/ MCE provides Dimethyl sulfoxide that complies with the inspection standards (Ch P) of Part 4 of the Chinese Pharmacopoeia (2020 Edition) Amicrobic low endotoxin can be used in various biochemical experiments such as drug dissolution
Medchemexpress LLC Otaplimastat (SP-8203) | 1176758-04-5 | 98.11% | 534.61 | 50 MG
Otaplimastat (SP-8203) is a matrix metalloproteinase (MMP) inhibitor that competitively blocks N-methyl-D-aspartate (NMDA) receptor-mediated excitotoxicity. It also exhibits anti-oxidant activity and can be used for research on brain ischemic injury.
- MMP inhibitor
- Blocks NMDA receptor-mediated excitotoxicity competitively
- Exhibits anti-oxidant activity
- Potential for research of brain ischemic injury
- Protects neuronal cells against NMDA-induced cell death
- Inhibits Ca2+ influx following activation of NMDA receptors in primary cultured neurons
- Suppresses H2O2-induced cell death and reactive oxygen species production
- Prevents ischemic neuronal death in the occlusion model of MCA in rats
- Attenuates impairment of stroke-induced motor function in rats
Medchemexpress LLC Spermidine-d6 | 2514812-10-1 | 96.1% | 5 MG
Spermidine-d6 is the deuterium labeled Spermidine, designed for research applications. It plays a role in maintaining cell membrane stability, increasing antioxidant enzyme activities, and improving photosystem II (PSII) and relevant gene expression. This compound significantly decreases H2O2 and O2.- contents. Deuteration, incorporating stable heavy isotopes into drug molecules, has gained attention for its potential to affect pharmacokinetic and metabolic profiles of drugs, making Spermidine-d6 valuable as a tracer and internal standard.
- Used as a tracer
- Internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Maintains cell membrane stability
- Increases antioxidant enzyme activities
- Improves photosystem II (PSII) and relevant gene expression
- Decreases H2O2 and O2.- contents