Glycosyl compounds
Medchemexpress LLC D-Galactose pentaace 100g
D-Galactose pentaacetate inhibits leucine-induced insulin release D-Galactose pentaacetate can be used for the research of persistent hyperinsulinemia in childhood or insulinoma[1][2]
![eMolecules 129541-42-0 | 5-Bromo-4-chloro-3-indolyl caprylate | Apollo Scientific | MFCD00083263 | 372.690 | C16H19BrClNO2 | 0.000 | CCCCCCCC(=O)Oc1c[nH]c2ccc(Br)c(Cl)c12 | 1g | 562460604](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502160386.JPG-250.jpg)
eMolecules 129541-42-0 | 5-Bromo-4-chloro-3-indolyl caprylate | Apollo Scientific | MFCD00083263 | 372.690 | C16H19BrClNO2 | 0.000 | CCCCCCCC(=O)Oc1c[nH]c2ccc(Br)c(Cl)c12 | 1g | 562460604
5-Bromo-4-chloro-3-indolyl caprylate | Apollo Scientific | 129541-42-0 | MFCD00083263 | 372.690 | C16H19BrClNO2 | 0.000 | CCCCCCCC(=O)Oc1c[nH]c2ccc(Br)c(Cl)c12 | 1g | 562460604
AdipoGen n-Octyl-beta-D-glucopyranoside
Chemical. CAS 29836-26-8. Formula C14H28O6. MW 292.4. Non-ionic detergent for the functional solubilization, isolation, purification and crystallograpy of membrane proteins. Mild, non-denaturing detergent that is used for the solubilization and reconstitution of membrane-bound proteins in their native state and for the preparation of lipid vesicles. Its well-defined chemical structure, small uniform micelles and high water solubility make it superior to most other non-ionic detergents for membrane solubilization. The high critical micelle concentration 0.7% of n-octylglucoside facilitates ready removal from final protein extracts by dialysis or gel filtration. Used in lysis and solubilisation buffers for bacterial lipoprotein preparations, mitochondrial extracts or for determination of protein content by BCA assay. Can be used in 2D electrophoresis.
Medchemexpress LLC D-(+)-Trehalose (standard) | 99-20-7 | 342.30 | 50 MG
D-(+)-Trehalose (Standard) is a laboratory chemical and analytical standard intended for research and analytical applications. It is used in the manufacture of various substances.
- For research use only
- Not fully validated for medical applications
Medchemexpress LLC Cimiracemoside D | 290821-39-5 | MFCD28411517 | 678.85 | 1 ML
Cimiracemoside D is a natural product isolated from Actaea racemosa, appearing as a white to off-white solid. It exhibits solubility in DMSO (100 mg/mL, 147.31 mM with sonication) and detailed protocols for preparing stock solutions and in vivo dissolution are available.
- Purity of 99.89%
- Isolated from Actaea racemosa
- Appears as a white to off-white solid
- Soluble in DMSO (100 mg/mL, 147.31 mM)
- Includes protocols for stock solution preparation
- Includes protocols for in vivo dissolution using various solvents
- Powder storage at -20°C for 3 years, 4°C for 2 years
- In-solvent storage at -80°C for 2 years, -20°C for 1 year
Medchemexpress LLC D-GsMTx4 | 1209500-46-8 | 99.4% | 4095.84 | 500 UG
D-GsMTx4 is a spider peptide and the D enantiomer of GsMTx4. It functions as an inhibitor of the mechanosensitive ion channel Piezo2. It also inhibits [Ca2+]i elevation and the mTOR and PI3K-Akt signaling pathways. This compound has been used in research related to mechanical stress, chronic pain, and idiopathic pulmonary fibrosis, and inhibits mechanical allodynia and thermal hyperalgesia.
- Inhibits mechanosensitive ion channel Piezo2
- Decreases phosphorylation levels of proteins in mTOR and PI3K-Akt signaling pathways
- Inhibits mechanical stimulation-evoked calcium increases
- Significantly inhibits mechanical allodynia and thermal hyperalgesia
- Used in research for mechanical stress, chronic pain, and idiopathic pulmonary fibrosis
Apexbio Technology LLC ISRIB (trans-isomer) 1597403-47-8 25mg
ISRIB (trans-isomer) (CAS 1597403-47-8) is a small molecule inhibitor of the integrated stress response (ISR) ISR activation involves the phosphorylation of eukaryotic initiation factor 2 (eIF2 ) by stress-sensitive kinases leading to reduced global protein synthesis and enhanced translation of select mRNAs ISRIB counteracts ISR signaling by reversing the translational suppression induced by phosphorylated eIF2 inhibiting production of ATF4 protein decreasing stress granule assembly and promoting polyribosome formation during endoplasmic reticulum (ER) stress ISRIB stabilizes and activates eIF2B by facilitating its dimerization Rodent studies demonstrate ISRIB s capacity to enhance hippocampal-dependent spatial and fear-related learning and memory highlighting its utility in neuroscience research
Medchemexpress LLC VEGF-D Rat HEK293 10ug
VEGF-D a growth factor stimulates proliferation migration and vessel permeability It is crucial for vascular development and maintenance of lymphatic endothelium VEGF-D binds and activates VEGFR-3 initiating essential signaling pathways Structurally it forms a non-covalent homodimer playing an intricate role in vascular processes VEGF-D Protein Rat (HEK293 Fc) is the recombinant rat-derived VEGF-D protein expressed by HEK293 with N-hFc labeled tag
Medchemexpress LLC Cathepsin D Mouse 100ug | 100ug
Cathepsin D Protein Mouse (HEK293 His) is an approximately 56 0 kDa mouse cathepsin D with a His tag Cathepsin D is a lysosomal aspartic protease of the pepsin family[1]
Medchemexpress LLC D-Galactose pentaace 10g
D-Galactose pentaacetate inhibits leucine-induced insulin release D-Galactose pentaacetate can be used for the research of persistent hyperinsulinemia in childhood or insulinoma[1][2]
Medchemexpress LLC KI696 isomer | 1799974-69-8 | 99.3% | 550.63 | C28H30N4O6S | 25 MG
KI696 isomer is the less active stereoisomer of KI696, a high-affinity probe that disrupts the Keap1-NRF2 interaction. Supplied as a white to off-white solid for research use, it is offered in solid and DMSO solution formats; follow recommended storage conditions for stability.
- Less active stereoisomer that disrupts the Keap1-NRF2 interaction.
- High purity (99.3%).
- White to off-white solid physical form.
- Molecular formula C28H30N4O6S; molecular weight 550.63.
- Available as solids and 10 mM solutions in DMSO.
- Store powder at -20°C and solutions at -80°C for long-term stability.
Medchemexpress LLC D-(+)-Trehalose | 99-20-7 | 342.30 | 500 MG
D-(+)-Trehalose is an orally active disaccharide that exhibits anti-desiccant and cryopreservative activities. It functions as an osmolyte and stress protectant, aiding in carbon storage and transport. It can be utilized as a food ingredient and a pharmaceutical excipient.
- Orally active disaccharide
- Exhibits anti-desiccant and cryopreservative activities
- Functions as an osmolyte and stress protectant
- Aids in carbon storage and transport
- Can be utilized as a food ingredient and pharmaceutical excipient
- No toxic effects on Chinese hamster ovary (CHO) cells at 5000 μg/mL
Medchemexpress LLC Prostaglandin D Synthase Antibody (YA1739) | 100 UL
Prostaglandin D Synthase Antibody (YA1739) is a rabbit-derived, non-conjugated IgG monoclonal antibody that targets Prostaglandin D Synthase. This protein acts as a glutathione-independent prostaglandin D synthase, converting prostaglandin H2 (PGH2) to prostaglandin D2 (PGD2). PGD2 plays various roles as a neuromodulator, a trophic factor in the central nervous system, and is involved in smooth muscle contraction/relaxation, as well as being a potent inhibitor of platelet aggregation. The related gene is primarily expressed in the brain, with studies suggesting its involvement in regulating non-rapid eye movement sleep.
- Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
- Stored at -20°C for 1 year, avoid repeated freeze/thaw cycles
- Liquid appearance
- Reactivity with human, mouse, and rat
- Applications: WB, IHC-P, IHC-F, ICC/IF
Medchemexpress LLC D-3263 hydrochloride | 1008763-54-9 | 98.12% | 409.95 | 100 MG
D-3263 hydrochloride is an enteric-coated, orally bioavailable transient receptor potential melastatin member 8 (TRPM8) agonist. It binds to and activates TRPM8, which may lead to an increase in calcium and sodium entry, disruption of calcium and sodium homeostasis, and induction of cell death in TRPM8-expressing tumor cells. D-3263 hydrochloride may also decrease dihydrotestosterone (DHT) levels, potentially contributing to its inhibitory effects on prostate cancer and benign prostatic hyperplasia (BPH).
- Binds to and activates TRPM8.
- Increases calcium and sodium entry into cells.
- Disrupts calcium and sodium homeostasis.
- Induces cell death in TRPM8-expressing tumor cells.
- Decreases dihydrotestosterone (DHT) levels.
- Inhibits prostate cancer and benign prostatic hyperplasia (BPH).