Monosaccharides
Medchemexpress LLC Lometrexol disodium | 120408-07-3 | 98.0% | 487.42 | C21H23N5Na2O6 | 5 MG
Lometrexol disodium is an antipurine antifolate research compound that inhibits glycinamide ribonucleotide formyltransferase (GARFT) and serine hydroxymethyltransferase 1/2 (hSHMT1/2), disrupting de novo purine synthesis and leading to cell cycle arrest and apoptosis. It is supplied as a disodium salt for biochemical and cellular studies.
- Potent GARFT and hSHMT1/2 inhibitor used to study purine metabolism.
- High purity: 98.0% suitable for analytical and biological assays.
- Molecular formula C21H23N5Na2O6 and molecular weight 487.42.
- Provided as a solid powder in small research pack sizes for convenience.
- Documentation available: data sheet, certificate of analysis, and safety data sheet.
Medchemexpress LLC Piperaquine phosphate | 85547-56-4 | 98.6% | 100 MG
Piperaquine phosphate is a bisquinoline antimalarial agent. It can be utilized in antimalarial research in conjunction with Artemisinin.
- Acts as a bisquinoline antimalarial agent
- Used in antimalarial research with artemisinin
- Reduces parasitemia in mice
- Extends median survival time in animal models with Plasmodium berghei parasites
Medchemexpress LLC Cromolyn (disodium) | 15826-37-6 | 89.2% | 50 MG
Cromolyn disodium (Standard) is the analytical standard for Cromolyn disodium. It is designed for research and analytical applications. This compound acts as an orally active GSK-3β inhibitor with an IC50 of 2.0 μM, and it also functions as a mast cell stabilizer. It works by inhibiting the release of mediators from mast cells, regulating reflex bronchoconstriction, and reducing non-specific bronchial hyperreactivity, making it relevant for bronchial asthma research.
- Orally active GSK-3β inhibitor
- Mast cell stabilizer
- Inhibits mediator release from mast cells
- Regulates reflex bronchoconstriction
- Reduces non-specific bronchial hyperreactivity
- Anti-inflammatory, anti-allergic, anti-histamine effects
- Anti-cancer and neuroprotective effects
Medchemexpress LLC K-Ras ligand-Linker Conjugate 6 | 2378261-89-1 | 100 MG
K-Ras ligand-Linker Conjugate 6 is a chemical compound with the formula C42H60N8O7 and a molecular weight of 788.98. This product appears as an oil and is stable under recommended storage conditions. It is intended for use as a laboratory chemical and for the manufacture of substances, strictly for research purposes by experienced personnel in appropriately equipped facilities.
- Identified for laboratory chemical applications
- Chemical formula: C42H60N8O7
- Molecular weight: 788.98
- Physical appearance: oil
- Stable under recommended storage conditions
- May cause skin and serious eye irritation
- May cause respiratory irritation
- Harmful if swallowed
Medchemexpress LLC Cyclic GMP-AMP (disodium); 3',3'-cGAMP (disodium) | 2407516-83-8 | 98.47% | 718.37 | 1 MG
cGAMP disodium is an endogenous second messenger that triggers interferon production in response to cytosolic DNA. It activates stimulator of interferon genes (STING), leading to a signaling cascade that produces type I interferons and other immune mediators. This product is suitable for various research applications.
- Promotes antigen-specific proliferation capacity of spleen cells
- Directly activates murine and human dendritic cells in vitro
- Increases transcription of IFNB1 in stimulated fibroblasts
- Induces an antiviral state and type I IFN secretion by activating ER-resident receptor STING
TARGETMOL CHEMICALS INC Transcrocetinate disodium 10MG
Also available in 1 mL, 1 mg, 5 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Transcrocetinate disodium (Disodium trans-crocetinate), extracted from saffron (Crocus sativus L.), is a high-affinity antagonist of NMDA receptor. Purity 99.22%
Medchemexpress LLC Mevalonate 5-phosphate trilithium | 868553-49-5 | 99.0% | 245.94 | 1 MG
Mevalonate 5-phosphate trilithium is a substrate of phosphomevalonate kinase and mevalonate-5-phosphate decarboxylase. It is for research use only and not sold to patients.
Medchemexpress LLC ERRα Ligand-Linker Conjugates 1 | 98.8% | 50 MG
ERRα Ligand-Linker Conjugates 1 incorporates a ligand for estrogen-related receptor alpha (ERRα), and a PROTAC linker, which recruit E3 ligases MDM2. It can be used in the synthesis of a series of PROTACs, such as PROTAC ERRalpha Degrader-1. This product is for research use only.
- Incorporates a ligand for estrogen-related receptor alpha (ERRα)
- Includes a PROTAC linker
- Recruits E3 ligases MDM2
- Can be used in the synthesis of PROTACs
- For research use only
![Alkali Scientific EDTA Disodium Salt [Ethylenediaminetetra acetic acid, disodium salt dihydrate], 2.5 Kg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000661061.jpg-250.jpg)
Alkali Scientific EDTA Disodium Salt [Ethylenediaminetetra acetic acid, disodium salt dihydrate], 2.5 Kg
EDTA Disodium Salt (2.5 kg) is a high-concentration chelating agent used for laboratory experiments that require the removal or sequestration of metal ions. This 2.5 kg package is ideal for large-scale applications in biochemistry, molecular biology, and other scientific fields where metal ion control is essential. EDTA works by binding to metal ions such as calcium, magnesium, and iron, preventing them from catalyzing unwanted chemical reactions or interfering with enzymatic activity. It is widely used in DNA and RNA extraction, enzyme assays, and metal ion quantification. Laboratories that conduct frequent experiments requiring consistent metal ion control benefit from this bulk packaging.
Medchemexpress LLC ADP-ribose-pNP disodium | 00-00-0 | 99.9% | 724.37 g/mol | C21H24N6Na2O16P2 | 5 MG
pNP-ADPr disodium is a colorimetric ADP-ribose p-nitrophenyl substrate used to measure poly(ADP-ribose) glycohydrolase (PARG) and ADP-ribosyl hydrolase 3 (ARH3) activity. It is supplied in small research pack sizes for enzymatic assays and enables continuous colorimetric monitoring of hydrolase activity.
- Colorimetric substrate for poly(ADP-ribose) glycohydrolase (PARG) and ARH3 assays.
- Enables the first continuous colorimetric assay format for PARG activity.
- Suitable for kinetic and end-point enzymatic assays.
- Supplied as the disodium salt for improved aqueous solubility.
- Available in small research pack sizes (1 mg, 5 mg, 10 mg).
- High analytical purity (~99.9%).
Medchemexpress LLC Sitagliptin phosphate monohydrate | 654671-77-9 | MFCD10001393 | 523.32 | 1 G
Sitagliptin phosphate monohydrate | 654671-77-9 | MFCD10001393 | 523.32 | 1 G
Medchemexpress LLC Lobenzarit disodium | 64808-48-6 | MFCD00941422 | 99.9% | 335.65 | C14H8ClNNa2O4 | 25 MG
Lobenzarit disodium is the disodium salt form of lobenzarit, supplied as a high-purity solid research reagent (CAS 64808-48-6) described as an anti-arthritic and anti-oxidative agent. It is intended for laboratory research use and is offered in small pack sizes suitable for preclinical and in vitro studies.
- High purity (≈99.9%) suitable for research applications.
- Solid form for easy weighing and handling.
- Supplied as the disodium salt for use in research studies.
- Available in multiple small pack sizes (5-500 mg) for preclinical work.
- Used as an anti-arthritic and anti-oxidative research compound.
Sigma Aldrich Fine Chemicals Biosciences Glucose-6-phosphate Dehydr
Glucose 6-phosphate dehydrogenase (G-6-P-DH) is a key regulatory enzyme in the first step of the pentose phosphate pathway. G-6-P-DH is a glycoprotein with a molecular mass of 128 kDa (gel filtration).
Medchemexpress LLC Piperaquine (phosphate) | 85547-56-4 | 98.6% | 25 MG
Piperaquine phosphate is a bisquinoline antimalarial agent. It can be used in antimalarial research in combination with Artemisinin.
- Bisquinoline antimalarial agent.
- Can be used in antimalarial research in combination with Artemisinin.
- In vivo, Piperaquine (10-90 mg/kg; a single i.p.) decreases parasitemia in mice.
- At a dose of 90 mg/kg, it resulted in stable body weights and active mice throughout the study.
- Purity: 98.62%.
Apexbio Technology LLC Phosphatase Inhibitor Cocktail (1 Tube, EDTA-Free, 100X)(Synonyms: Phosphatase Inhibitor Cocktail, Phosphatase Inhibitor Mix, Phosphatase Inhibitor Set), 1ml.
Phosphatase Inhibitor Cocktail (1 Tube EDTA-Free 100X) provides comprehensive inhibition of various phosphatases including acid and alkaline phosphatases serine/threonine phosphatases (e g PP1 PP2A PP2B) and protein tyrosine phosphatases (PTPs) By suppressing phosphatase enzymatic activities it preserves phosphorylation states of proteins in lysates from mammalian plant yeast insect or bacterial samples ensuring more accurate downstream analysis It is applicable in protein lysate preparations immunoprecipitations nuclear extracts and processing of fixed tissues (e g FFPE) to maintain phosphorylation modifications