Monosaccharides
Medchemexpress LLC D-Glucose (Standard) | 50-99-7 | 99.8% | 100 MG
D-Glucose (Standard) is the analytical standard of D-Glucose. It is the naturally occurring form of glucose and the most abundant monosaccharide, playing a critical role in general metabolism and cellular metabolic status signaling. This product is intended for research and analytical applications.
- Analytical standard for D-Glucose
- Naturally occurring form of glucose
- Most abundant monosaccharide
- Critical component of general metabolism
- Significant signaling molecule for cellular metabolic status and stress response
- Used as a reference standard for assays
- Commonly employed in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS
Medchemexpress LLC D-Glucose-13C6 | 110187-42-3 | MFCD00144088 | 99.9% | 1 ML
D-Glucose-13C6 is a stable isotope-labeled counterpart of D-glucose. It can be used as a metabolic tracer for glucose-related synthetic catabolism or as a synthesis ingredient, minimal media reagent, and internal standard. It is for research use only.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Stable isotope-labeled counterpart of D-glucose
- Traces glucose-related synthetic catabolism
- Synthesis ingredient
- Minimal media reagent
Medchemexpress LLC D-Glucose-13C6 | 110187-42-3 | 99.9% | 1 G
D-Glucose-13C6 is a stable isotope-labeled counterpart of D-glucose. It can be utilized as a metabolic tracer to track glucose-related synthetic catabolism, or as a synthesis ingredient, minimal media reagent, and internal standard.
- Stable isotope-labeled counterpart of D-glucose
- Metabolic tracer for glucose-related synthetic catabolism
- Synthesis ingredient
- Minimal media reagent
- Internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC K-Ras ligand-Linker Conjugate 4 | 2378261-83-5 | 98.8% | 50 MG
K-Ras ligand-Linker Conjugate 4 integrates a ligand for K-Ras recruiting moiety and a PROTAC linker, which recruits E3 ligases (VHL, CRBN, MDM2, IAP). It is used in the synthesis of a potent PROTAC K-Ras degrader that demonstrates ≥70% degradation efficacy in SW1573 cells. PROTACs utilize the intracellular ubiquitin-proteasome system for selective degradation of target proteins by connecting a ligand for an E3 ubiquitin ligase with a ligand for the target protein.
- Incorporates a ligand for K-Ras recruiting moiety.
- Features a PROTAC linker to recruit E3 ligases.
- Used in the synthesis of potent protein degraders.
- Facilitates selective degradation of target proteins.
- Leverages the ubiquitin-proteasome system.
TARGETMOL CHEMICALS INC Pemetrexed disodium 500MG
Also available in 1 g, 1 mL, 25 mg, 50 mg, 100 mg, 200 mg and bulk. Please contact Fisher for quotes. Pemetrexed disodium (LY-231514) is a parenterally administered folate antagonist and antineoplastic agent, used in the treatment of non-small cell lung cancer and malignant mesothelioma. Pemetrexed disodium therapy has been associated with moderate rates of serum enzyme elevations during therapy, but has not been convincingly linked to instances of acute, clinically apparent liver injury. Purity 99.92%
![Alkali Scientific EDTA Disodium Salt [Ethylenediaminetetra acetic acid, disodium salt dihydrate], 10 Kg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000661059.jpg-250.jpg)
Alkali Scientific EDTA Disodium Salt [Ethylenediaminetetra acetic acid, disodium salt dihydrate], 10 Kg
EDTA Disodium Salt (10 kg) is a highly concentrated chelating agent used for a variety of laboratory applications. Its ability to sequester metal ions makes it essential in preventing metal ion catalysis and ensuring accurate results in chemical reactions. This 10 kg bulk package is commonly used in molecular biology, biochemistry, and microbiology laboratories. EDTA effectively inhibits enzymes that require metal ions as cofactors, preventing undesired reactions during sample preparation, analysis, and preservation. This large volume is perfect for laboratories requiring frequent use of chelating agents in large-scale experiments or industrial applications, where controlling the concentration of metal ions is critical.
![Alkali Scientific EDTA Disodium Salt [Ethylenediaminetetra acetic acid, disodium salt dihydrate], 250 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000661060.jpg-250.jpg)
Alkali Scientific EDTA Disodium Salt [Ethylenediaminetetra acetic acid, disodium salt dihydrate], 250 G
EDTA Disodium Salt (250 g) is a versatile chelating agent used in various laboratory applications to bind metal ions and prevent metal-catalyzed reactions. This reagent is commonly used in molecular biology, biochemistry, and analytical chemistry for tasks like DNA extraction, protein purification, and enzyme inhibition studies. EDTA functions by sequestering divalent and trivalent metal ions, preventing them from interfering with chemical reactions or biological processes. Its ability to stabilize samples by controlling metal ion concentration makes it an essential component in laboratory research, clinical diagnostics, and various analytical techniques that require metal ion control.
Sigma Aldrich Fine Chemicals Biosciences Glucose-6-phosphate Dehydr
Glucose 6-phosphate dehydrogenase (G-6-P-DH) is a key regulatory enzyme in the first step of the pentose phosphate pathway. G-6-P-DH is a glycoprotein with a molecular mass of 128 kDa (gel filtration).
Medchemexpress LLC USP7 ligand-linker conjugate 1 | 10 MG
USP7 Ligand-Linker Conjugates 1 is a ligand-linker conjugate intended as a building block for PROTAC synthesis that targets USP7. It links a USP7-binding ligand to a PROTAC-compatible linker to enable recruitment of E3 ligases and subsequent target degradation. Supplied for research use in medicinal chemistry and chemical biology under appropriate laboratory conditions.
- Designed for PROTAC synthesis targeting USP7.
- Combines a USP7-binding ligand with a PROTAC-compatible linker to recruit E3 ligases.
- Molecular formula C38H49N5O6; molecular weight 671.83.
- Supplied in small research quantities for chemical biology and medicinal chemistry.
- Store pure material at -20°C for long-term stability; see datasheet for solvent storage guidance.
Medchemexpress LLC Cromolyn (sodium) | 15826-37-6 | MFCD00057744 | 89.2% | 512.3 g/mol | C23H14Na2O11 | 10 MG
Cromolyn disodium (disodium cromoglycate) is the sodium salt form of cromolyn supplied as a solid research reagent for biochemical and pharmacological studies. The material is provided in a small, accurately measured package suitable for analytical use and reference standards. It has CAS number 15826-37-6 and molecular formula C23H14Na2O11.
- Solid powder form for easy weighing and dissolution
- Suitable as a reference standard for analytical assays
- Commonly used in pharmacology and biochemical research applications
- Verified chemical identity with CAS 15826-37-6
- Small 10 MG package size for small-scale experiments and analytical testing
Medchemexpress LLC Glucose-6-phosphate dehydrogenase | 9001-40-5 | 108.6 kDa | 1KU
Glucose-6-phosphate dehydrogenase is the rate-limiting enzyme of the pentose phosphate pathway, provided as a solid enzyme preparation from microorganisms for biochemical research and enzymatic assays involving NADPH generation and oxidative stress pathways.
- Appearance: White to off-white solid.
- CAS number: 9001-40-5.
- Size: 1 KU.
- Enzyme activity: ≥150 U/mg (solid).
- Specific activity: ≥500 U/mg (protein).
- Molecular weight: 108.6 kDa.
- Optimal pH: 7.0-9.0.
- Unit definition: One unit oxidizes 1 μmol D-glucose-6-phosphate per minute at pH 7.8 and 37°C.
- Storage and shipping: Room temperature shipping in continental US; follow certificate of analysis for storage conditions.
Medchemexpress LLC Cuda disodium | 98.0% | 386.48 g/mol | C19H36N2Na2O3 | 5 MG
CUDA disodium is a potent, research-use small molecule inhibitor of soluble epoxide hydrolase (sEH) that modulates PPARα activity. Reported IC50 values are 11.1 nM (mouse sEH) and 112 nM (human sEH). Supplied as a 5 mg sample with 98.0% purity, it is intended for biochemical and pharmacological research in lipid metabolism and cardiovascular disease models.
- Potent sEH inhibition with reported IC50s of 11.1 nM (mouse) and 112 nM (human).
- Enhances peroxisome proliferator-activated receptor alpha activity in cellular models.
- High purity (98.0%) suitable for biochemical assays.
- Small quantity packaging (5 mg) for screening and early-stage studies.
- Storage recommendations provided for stability in solvent and dry conditions.
Medchemexpress LLC Sitagliptin phosphate monohydrate | 654671-77-9 | 99.8% | 523.32 | 1 ML
Sitagliptin phosphate monohydrate, also known as MK-0431, is an orally active and highly selective DPP4 inhibitor. It works by blocking the degradation of glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP), thereby increasing active incretin levels. This compound can also directly stimulate GLP-1 secretion by intestinal L cells through activation of the cAMP/PKA and ERK1/2 pathways, independently of DPP-4. It exhibits protective effects on pancreatic islet grafts in type 1 diabetes models and is used for studying both type 1 and type 2 diabetes.
- Orally active and highly selective DPP4 inhibitor.
- Blocks degradation of GLP-1 and GIP.
- Increases active incretin levels.
- Directly stimulates GLP-1 secretion.
- Protective effects on pancreatic islet grafts.
- Used for studying type 1 and type 2 diabetes.