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Filtered Search Results
Medchemexpress LLC Fludarabine (phosphate) | 75607-67-9 | 99.8% | C10H13FN5O7P | 1 ML
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Fludarabine phosphate is an analogue of adenosine and deoxyadenosine, which competes with dATP for incorporation into DNA and inhibits DNA synthesis. This compound is for research use only and has not been fully validated for medical applications.
- Significantly reduces cell viability in a dose-dependent manner
- Leads to complete regressions of all tumors and cures of all mice in some in vivo studies
- Used for research purposes
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Medchemexpress LLC Fludarabine (phosphate) | 75607-67-9 | 99.8% | C10H13FN5O7P | 50 MG
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Fludarabine phosphate is an analogue of adenosine and deoxyadenosine. It competes with dATP for incorporation into DNA and inhibits DNA synthesis. This compound significantly reduces cell viability in a dose-dependent manner.
- Competes with dATP for incorporation into DNA
- Inhibits DNA synthesis
- Significantly reduces cell viability in a dose-dependent manner
- Causes complete regression of D54 tumors in mice
- For research use only
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TARGETMOL CHEMICALS INC SIGMA-LIGAND-1 5MG
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Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Sigma-LIGAND-1 is a selective Sigma Receptor ligand with an IC50s of 16 nM 19 nM at the DTG site and the PPP site respectively. Sigma-LIGAND-1 has a Ki of 4000 nM at the dopamine D2 receptor. purity: 100%
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Medchemexpress LLC Clodronate (disodium tetrahydrate) | 88416-50-6 | MFCD02940846 | 99.9% | 360.92 g/mol | CH10Cl2Na2O10P2 | 1 ML
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Clodronate (disodium tetrahydrate) is the disodium salt tetrahydrate of clodronic acid, a first-generation bisphosphonate used in biochemical and cell biology research to inhibit bone resorption, modulate macrophage populations, and study mineralization processes. It is supplied as solid material and as ready-to-use aqueous solutions for in vitro applications.
- High reported purity (99.86%) suitable for research assays.
- Available as a 10 mM aqueous solution and as solid quantities for flexibility.
- Molecular weight 360.92 g/mol for precise dosing calculations.
- Useful for studies of bone resorption, macrophage depletion, and calcification.
- Includes SDS and COA documentation for quality control.
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Medchemexpress LLC Zn(II)-EDTA disodium tetrahydrate | 176736-49-5 | MFCD00151728 | 95.0% | 471.63 g/mol | C10H20N2Na2O12Zn | 500 G
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Zn(II)-EDTA disodium tetrahydrate is a zinc chelate reagent supplied as a crystalline solid tetrahydrate for research and analytical use. It functions as a metal-chelating agent in biochemical assays, sample preparation, and analytical workflows where coordinated zinc complexes are required.
- Metal chelating agent for zinc complexation.
- Suitable for biochemical assays and analytical applications.
- Supplied as a stable solid tetrahydrate for easy weighing and storage.
- Typical purity 95.0%, appropriate for research use.
- Available in laboratory pack sizes including 500 G.
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Medchemexpress LLC 2- 5-Oxo-5H-Chromeno 5Mg | HY-W585894-5MG
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2- 5-Oxo-5H-Chromeno 5Mg
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Medchemexpress LLC Phosphocreatine disodium hydrate | 19333-65-4 | 99.57% | 100 MG
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Phosphocreatine (disodium hydrate) is an organic compound naturally found in the skeletal muscles of vertebrates. It demonstrates several protective effects:
- Enhances antioxidant activity.
- Activates the TAK1 pathway to protect the heart.
- Normalizes mitochondrial function and reduces oxidative stress through the Akt-mediated Nrf2/HO-1 pathway.
- Provides renal protection by suppressing apoptosis and reactive oxygen species (ROS) generation via the ERK-mediated Nrf-2/HO-1 pathway.
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Alkali Scientific EDTA Disodium Salt [Ethylenediaminetetra acetic acid, disodium salt dihydrate], 500 G
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EDTA Disodium Salt (500 g) is a reliable chelating agent that is essential for controlling metal ions in laboratory settings. This reagent is commonly used in molecular biology and biochemistry experiments to prevent metal-catalyzed reactions that could compromise experimental results. EDTA works by forming stable complexes with metal ions, preventing them from interacting with other compounds in the sample. It is particularly useful in DNA extractions, enzyme inhibition studies, and protein purification protocols. The 500 g size is perfect for small-to-medium-scale laboratory use, making it a cost-effective solution for frequent metal ion control needs in research applications.
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Medchemexpress LLC Benzoic acid, 2-[(2-carboxyphenyl)amino]-4-chloro-, disodium salt | 64808-48-6 | MFCD00941422 | 99.9% | 335.65 g·mol⁻¹ | C14H8ClNNa2O4 | 5 MG
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Lobenzarit disodium is the disodium salt form of lobenzarit (CCA), a small-molecule anti-arthritic and antioxidant agent supplied as a purified reagent for preclinical in vitro and in vivo research. It is used to study anti-inflammatory effects, modulation of reactive oxygen species, and related pharmacological activities.
- Anti-arthritic and antioxidant small molecule for preclinical research.
- High purity reagent (>99.9%).
- Disodium salt form for improved aqueous handling compared with the free acid.
- Suitable for in vitro and in vivo anti-inflammatory and antioxidant assays.
- Molecular formula C14H8ClNNa2O4; molecular weight 335.65 g·mol⁻¹.
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Medchemexpress LLC Zinc(II) ethylenediaminetetraacetic acid disodium tetrahydrate | 176736-49-5 | MFCD00151728 | 95.0% | 471.63 g/mol | C10H20N2Na2O12Zn | 1 KG
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Zinc(II) ethylenediaminetetraacetic acid disodium tetrahydrate is the zinc salt of EDTA supplied as a crystalline reagent for laboratory and life-science research. It is used as a chelating agent in metal-binding studies, analytical assays, and biochemical applications where controlled zinc complexation is required.
- Acts as a chelating agent for zinc and other metal ions.
- Suitable for biochemical assays and analytical applications.
- Provided as a white to off-white crystalline powder.
- Purity approximately 95.0% as supplied.
- Molecular weight 471.63 g/mol; formula C10H20N2Na2O12Zn.
- Available in a 1 kg package for bulk laboratory use.
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Medchemexpress LLC IACS-8803 disodium | 2243079-36-7 | 99.97% | 25 MG
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IACS-8803 disodium is a highly potent cyclic dinucleotide STING agonist that has demonstrated robust systemic antitumor efficacy. Studies show it exhibits superior antitumor activity, particularly via intra-tumoral injection.
- Highly potent cyclic dinucleotide STING agonist
- Demonstrates robust systemic antitumor efficacy
- Exhibits superior antitumor activity via intra-tumoral injection
- Store solid at -20°C under nitrogen, away from moisture
- Store in solvent at -80°C for 6 months or -20°C for 1 month, under nitrogen, away from moisture
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Medchemexpress LLC K-Ras ligand-Linker Conjugate 5 | 97.0% | 50 MG
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K-Ras ligand-Linker Conjugate 5 incorporates a ligand for K-Ras recruiting moiety, and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP).
- Incorporates a ligand for K-Ras recruiting moiety
- Features a PROTAC linker
- Recruits E3 ligases (such as VHL, CRBN, MDM2, and IAP)
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Medchemexpress LLC Dipotassium hydrogen phosphate | 7758-11-4 | MFCD00011383 | 100.0% | 174.17 g·mol⁻¹ | HK2O4P | 50 G
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Dipotassium hydrogen phosphate is an inorganic, dibasic potassium phosphate salt commonly used as a buffering agent and phosphate source in laboratory, biochemical, and formulation applications. It is supplied as a high-purity, water-soluble solid suitable for buffer preparation, pH control, and pharmaceutical excipient research.
- High purity (99.95%) for analytical and research use.
- Reliable buffering capacity for precise pH control.
- Water soluble for easy buffer preparation.
- Suitable as a phosphate source in biochemical and molecular biology workflows.
- Stable solid form with extended shelf life when stored properly.
- Available in multiple pack sizes for lab and scale-up needs.
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Medchemexpress LLC Tripropyl phosphate-d21 | 1219794-92-9 | 98.0% | 245.36 | 25 MG
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Tripropyl phosphate-d21 is a deuterium labeled version of Tripropyl phosphate. It is intended for research use only and can be used as a tracer or an internal standard for quantitative analysis. Deuterium substitution has shown potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
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Medchemexpress LLC Adenylyl-imidodiphosphate disodium | 7414-56-4 | MFCD32646673 | 99.4% | 549.17 | C11H16N5Na2O12P3 | 10 MG
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AMP-PCP disodium is a non-hydrolyzable ATP analogue (adenylyl-imidodiphosphate disodium) used to mimic ATP binding in biochemical and structural studies. It binds the N-terminal domain of Hsp90 with a reported Kd of 3.8 μM and favors formation of the active Hsp90 homodimer, making it useful for probing ATP-dependent enzyme mechanisms and protein complex assembly.
- Non-hydrolyzable ATP analogue for stabilizing ATP-bound states.
- Binds Hsp90 N-terminal domain (Kd ≈ 3.8 μM), facilitating homodimer formation.
- Provided as the disodium salt with high purity (99.4%).
- High aqueous solubility: H2O 100 mg/mL; PBS 50 mg/mL (ultrasonic recommended).
- Storage recommendations: solid -20°C; in solvent -80°C for 6 months or -20°C for 1 month.
- Supplied in small research pack sizes suitable for biochemical assays.
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