Sugar acids and derivatives
Medchemexpress LLC Integrin alpha V bet 500ug | 500ug
Integrin V beta 5 proteins specifically the -V (ITGAV) subunit are multifunctional receptors for ligands such as vitronectin and fibronectin and recognize RGD sequences ITGAV ITGB3 binds fractalkine and acts as a coreceptor in CX3CR1-dependent signaling Integrin alpha V beta 5 Protein Human (HEK293 His-Avi) is a recombinant protein dimer complex containing human-derived Integrin alpha V beta 5 protein expressed by HEK293 with C-Avi C-His labeled tag Integrin alpha V beta 5 Protein Human (HEK293 His-Avi) has molecular weight of 85-160 kDa
Medchemexpress LLC 4-methylumbelliferyl β-D-glucopyranoside | 18997-57-4 | MFCD00063694 | >98.0% | 338.31 g/mol | C16H18O8 | 500MG
4-Methylumbelliferyl β-D-glucopyranoside is a fluorogenic β-D-glucoside substrate for measuring β-glucosidase activity. Upon enzymatic cleavage it releases 4-methylumbelliferone (4-MU), a highly fluorescent product useful for quantitative enzymatic assays and high-throughput screening. The excitation maxima of 4-MU are pH-dependent, and the compound is provided as a white to off-white powder suitable for laboratory use.
- Fluorogenic substrate for β-glucosidase assays.
- Releases 4-methylumbelliferone with emission ~445-454 nm.
- Excitation maxima depend on pH (≈330, 370, 385 nm).
- High purity (≥98.0% by HPLC) for reliable results.
- Available in multiple pack sizes, including 500 MG.
- Molecular formula C16H18O8; molecular weight 338.31 g/mol.
Medchemexpress LLC Heparin calcium | 37270-89-6 | 3600-5000 Da | 50 MG
Heparin calcium (MW 3600-5000) is a low-molecular-weight heparin calcium salt used as an anticoagulant reagent for biochemical and pharmacological research. It forms a complex with antithrombin III to inhibit thrombin and other activated clotting factors, preventing fibrin formation. The material is a heterogeneous sulfated polysaccharide mixture provided as a dry reagent for laboratory use.
- Molecular weight 3600-5000 Da
- Anticoagulant activity via antithrombin III-mediated inhibition of clotting factors
- Intended for biochemical and pharmacological research applications
- Heterogeneous sulfated polysaccharide mixture, not a single defined molecule
- Supplied as a dry reagent suitable for in vitro assays
Medchemexpress LLC D-Glucuronic acid | 6556-12-3 | 1 ML
D-Glucuronic acid is a crucial component of various anti-inflammatory proteoglycans, playing a role in embryonic development and inhibiting cell aggregation. This compound and its derivatives are known for their liver detoxifying properties and have demonstrated anti-tumor activity.
- Promotes early embryonic development
- Inhibits cell aggregation
- Functions as a liver detoxifier
- Derivatives possess anti-tumor activity
- Activates Toll-like receptor 4 (TLR4)
Medchemexpress LLC [Ala11,D-Leu15]-Orexin B(human) | 532932-99-3 | 98.3% | 2857.26 | 10 MG
[Ala11,D-Leu15]-Orexin B(human) is a potent and selective orexin-2 receptor (OX2) agonist, demonstrating a 400-fold selectivity for OX2 (EC50=0.13 nM) over OX1 (52 nM).
- Potent and selective OX2 agonist
Medchemexpress LLC Plantainoside D | 147331-98-4 | 99.9% | 640.59 g/mol | C29H36O16 | 10 MG
Plantainoside D is a phenylethanoid glycoside research reagent reported to inhibit IKK-β and angiotensin-converting enzyme (ACE). It modulates voltage-dependent calcium channels and the PKC signaling cascade, reduces reactive oxygen species and NF-κB activation, and is used in studies of neuroprotection, anti-inflammation, antioxidant activity, and antihypertensive mechanisms.
- Phenylethanoid glycoside with IKK-β and ACE inhibitory activity.
- Modulates VDCCs and suppresses PKC signaling.
- Reduces ROS generation and inhibits NF-κB activation.
- High purity: 99.9%.
- CAS number 147331-98-4.
- Available as 10 MG solid and in DMSO solution formats for assays.
Medchemexpress LLC Lucifer Yellow CH (dilithium salt) | 67769-47-5 | 98.4% | 25 MG
Lucifer Yellow CH (dilithium salt) is a high-intensity fluorescent probe containing free hydrazyl groups. It reacts with fatty aldehydes at room temperature and is used as a biological tracer to monitor neuronal branching and regeneration, detect and characterize gap junctions, and enable selective ablation of cells after aldehyde fixation. It exhibits maximum excitation/emission at 430 nm/540 nm.
- High-intensity fluorescent probe
- Reacts with fatty aldehydes at room temperature
- Monitors neuronal branching and regeneration
- Detects and characterizes gap junctions
- Enables selective ablation of cells after aldehyde fixation
- Used for cell imaging and staining
- Evaluates gap junction functionality
Medchemexpress LLC MAC-545496 | 838810-96-1 | 98.0% | 100 MG
MAC-545496 is a nanomolar inhibitor of glycopeptide-resistance-associated protein R (GraR), exhibiting strong binding affinity (Kd ≤ 0.1 nM). This antivirulence agent reverses β-lactam resistance in Methicillin-resistant strains (MRSA) and is intended for research use only.
- Nanomolar inhibitor of glycopeptide-resistance-associated protein R (GraR)
- Exhibits strong binding affinity to full-length GraR protein (Kd ≤ 0.1 nM)
- Reverses β-lactam resistance in MRSA strains
- Synergizes with Cefuroxime and Oxacillin against MRSA
- Inhibits mprF expression and citrate-induced biofilm formation
- Effective monotherapy for MRSA-infected Galleria mellonella larvae in vivo