Sugar acids and derivatives
Medchemexpress LLC Beta-1 | 2924598-24-1 | C37H28IN3S2 | 25 MG
BETA-1 is the first twisted intramolecular charge transfer (TICT)-aggregation-induced emission (AIE) integration molecule. It emits cyan fluorescence in lipid droplets (LDs) and red fluorescence in mitochondria. This molecule can be used for the simultaneous and dual-color imaging of LDs and mitochondria in vivo and in vitro.
- Simultaneous and dual-color imaging of lipid droplets and mitochondria in vivo and in vitro
- Suitable for imaging of lipid droplets and mitochondria in live cells
- Emits cyan fluorescence with excitation at 405 nm and emission at 430-500 nm
- Emits red fluorescence with excitation at 561 nm and emission at 600-700 nm
Medchemexpress LLC Integrin alpha 5 beta 1 protein, human (biotinylated, HEK293, His-Avi) | 95.0% | 50UG
Biotinylated human integrin alpha 5 beta 1 is a recombinantly produced heterodimer expressed in HEK293 cells and supplied as a lyophilized powder with Avi and 8xHis tags. The protein is glycosylated (approx. 110-140 kDa), of high purity, and formulated with trehalose to preserve activity for binding assays and assay development.
- Lyophilized, stable formulation for long-term storage.
- Biotinylated for immobilization on streptavidin surfaces.
- Expressed in mammalian cells to preserve native glycosylation.
- C-terminal Avi and 8xHis tags for detection and purification.
- High purity as determined by SDS-PAGE (>95%).
- Low endotoxin level (<1 EU/μg) suitable for sensitive assays.
- Provided with certificate of analysis and safety data sheet.
- Reconstitute to at least 100 μg/mL in ddH2O for optimal performance.
Sigma Aldrich Fine Chemicals Biosciences Polygalacturonic acid | 25990-10-7 | MFCD00131972 | 25g
Polygalacturonic acid | Purity: 85% | 25990-10-7 | MFCD00131972 | 25g
Apexbio Technology LLC PKH67 Green Fluorescent Cell Linker Kit(Synonyms: PKH67 Cell Labeling Kit, PKH67 Fluorescent Dye Kit, PKH67 Green Fluorescent Cell Dye), 250T.
PKH67 Green Fluorescent Cell Linker Kit is designed for fluorescent labeling of cell membranes The kit utilizes the green fluorescent probe PKH67 a lipophilic dye that integrates stably into lipid regions of the plasma membrane emitting bright green fluorescence Upon cell division PKH67 distributes evenly among progeny cells causing fluorescence intensity to diminish incrementally with cell proliferation Due to its stability low cytotoxicity and minimal staining of adjacent cells PKH67 is widely applied in vitro and in vivo for tracking cell migration localization and monitoring cell proliferation dynamics Additionally PKH67 can be combined with other fluorescent dyes such as PKH26 for multiplex cell-labeling studies
Ambeed 2R 3R 4S 5S 6S 2Bromo6 methox
(2R,3R,4S,5S,6S)-2-Bromo-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate, 21085-72-3, 97%
Medchemexpress LLC PROTAC BET-binding moiety 2 | 916493-82-8 | 99.77% | 444.89 | 1 ML
PROTAC BET-binding moiety 2 is an inhibitor of BET bromodomain. It is for research use only.
- Inhibitor of BET bromodomain.
- Appearance: solid
- Color: white to off-white
Medchemexpress LLC D-Glucuronic acid sodium salt monohydrate | 207300-70-7 | 10 G
D-Glucuronic acid sodium salt monohydrate is a primary component of several anti-inflammatory proteoglycans, which can foster embryonic development and hinder cell aggregation. When metabolized into ethyl glucuronide, it activates Toll-like receptor 4 (TLR4), leading to pain. This compound and its derivative, glucurono-lactone, can act as liver detoxifiers for human health prevention, with its derivatives also exhibiting anti-tumor activity.
- Purity: 98.0%
- Molecular weight: 234.14
- Formula: C6H11NaO8
- Appearance: Solid, white to off-white
- Acts as a component of anti-inflammatory proteoglycans
- Promotes early embryonic development
- Inhibits cell aggregation
- Functions as a liver detoxifier
- Derivatives show anti-tumor activity
- Activates Toll-like receptor 4 (TLR4) when metabolized
- Categorized as a ketone, aldehyde, and acid
Medchemexpress LLC D-Iditol | 25878-23-3 | MFCD09951922 | 98.0% | 182.17 g/mol | C6H14O6 | 10 MG
D-Iditol is a fungal metabolite and sugar alcohol that accumulates in galactokinase deficiency. It is supplied as a white to off-white solid with ≥98.0% purity for research use only and is commonly used as an endogenous metabolite reference or reagent in biochemical and metabolic studies.
- High purity: 98.0% (manufacturer specification).
- Molecular weight 182.17 g/mol; formula C6H14O6.
- White to off-white solid suitable for analytical and synthetic applications.
- Stable when stored sealed at 4°C; in solvent: -80°C (6 months) or -20°C (1 month).
- Suitable for biochemical, metabolic, and analytical research workflows.
Medchemexpress LLC Lucifer Yellow CH dipotassium salt | 71206-95-6 | MFCD00013445 | 99.8% | 521.57 | C13H9K2N5O9S2 | 10 MG
Lucifer Yellow CH dipotassium salt is a high-intensity fluorescent tracer used in neuroscience and cell biology for intracellular labeling, neuronal tracing, gap junction analysis, and selective cell visualization. Supplied as the dipotassium salt with high reported purity, it is suitable for fluorescence microscopy and experiments requiring reliable, fixable fluorescent markers.
- High-intensity fluorescence for sensitive detection.
- Useful for neuronal tracing and monitoring neuronal branching.
- Enables gap junction detection and characterization.
- Reactive hydrazyl groups allow fixation and labeling with aldehyde-based methods.
- Suitable for fluorescence microscopy and electrophysiological assays.
AdipoGen 3OH-C10-L-HSL
Chemical. CAS 192883-12-8. Formula C14H25NO4. MW 271.35. Synthetic. N-3-hydroxydecanoyl-L-homoserine lactone is a small diffusible signaling molecule secreted by various bacteria and involved in quorum sensing, thereby controlling gene expression and affecting cellular metabolism. This lactone is produced via lactonolysis from 3-oxodecanoyl-homoserine lactone, altering quorum sensing or contributing to quorum quenching. The applications of this molecule include regulation of virulence and exoproteases.
Medchemexpress LLC Azido-PEG4-beta-D-glucose | 1609083-15-9 | 99.9% | 381.38 | 25 MG
Azido-PEG4-beta-D-glucose is a PEG-based PROTAC linker that facilitates the synthesis of PROTACs. This click chemistry reagent contains an Azide group, allowing it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups.
- PEG-based PROTAC linker
- Utilized in PROTAC synthesis
- Functions as a click chemistry reagent
- Contains an azide functional group
- Participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Enables strain-promoted alkyne-azide cycloaddition (SPAAC)
- Intended for research use only
Medchemexpress LLC BSJ-04-122 | 2513289-74-0 | 99.9% | 313.74 g/mol | C15H12ClN5O | 10 MG
BSJ-04-122 is a covalent dual inhibitor of the MAP kinase kinases MKK4 and MKK7 developed for research use. It demonstrates potent enzymatic inhibition (IC50 4 nM for MKK4; 181 nM for MKK7) and is applied in studies of cancer biology and MAPK signaling. The compound is supplied as a solid with high chemical purity and recommended storage conditions for both powder and solution forms.
Medchemexpress LLC UDP-3-O-acyl-GlcNAc | 108636-29-9 | 1 MG
UDP-3-O-acyl-GlcNAc is an E. coli metabolite involved in the 3-deoxy-D-manno-octulosonate (KDO) biosynthesis pathway. It has a molecular weight of 833.71 and a chemical formula of C31H53N3O19P2. This product is for research use only.
- Molecular weight: 833.71
- Formula: C31H53N3O19P2
- Initial source: Microorganisms (Escherichia)
- For research use only
Apexbio Technology LLC Cyclosporin D 63775-96-2 25mg
Cyclosporin D (CAS 63775-96-2) is a structural analogue of Cyclosporin A with comparatively reduced immunosuppressive activity Mechanistically it weakly inhibits lymphocyte proliferation induced by mitogens such as PHA PWM PMA and Ca 2 and suppresses Ca 2 /calmodulin-dependent phosphorylation of elongation factor 2 (EF-2) in mouse pancreatic cells In preclinical models Cyclosporin D overcomes Adriamycin resistance in multidrug-resistant ovarian cancer cells and inhibits TPA-induced ear edema and alkaline phosphatase activity in mice Additionally it displays inhibitory effects on the growth of malarial parasites both in vitro and in vivo Cyclosporin D serves as a standard in Cyclosporin A quantification and as a research tool in immunology oncology and antiparasitic studies