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C24:1 ceramide (d18:1/24:1(15Z)) is a long-chain monounsaturated ceramide supplied as a high-purity research reagent for biochemical and lipidomics studies. It is provided as a solid standard suitable for analytical assays, lipid formulation, and cell signaling research.
High purity for reproducible analytical results.
Suitable for lipidomics and biochemical assays.
Solid standard, easy to weigh and store.
Supports studies of cell signaling and apoptosis.
Stable under recommended storage conditions.
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C6 NBD ceramide is a fluorescent short-chain ceramide analog used as a Golgi apparatus probe in live and fixed cells. It is cell-permeable and is metabolized to fluorescent sphingomyelin and glucosylceramide, enabling visualization of sphingolipid transport, Golgi morphology, and related cellular processes (Ex 466 nm, Em 536 nm).
Provides bright green fluorescence for imaging (Ex 466 nm, Em 536 nm).
Cell membrane permeable for live and fixed cell labeling.
Metabolized to fluorescent sphingomyelin and glucosylceramide for metabolism studies.
High purity (99.3%) for consistent experimental results.
Supplied as a 1 mg vial suitable for small-scale assays.
Store sealed at -20°C; in solvent, store at -80°C for up to 6 months or -20°C for up to 1 month.
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C17 ceramide (d18:1/17:0) is a synthetic ceramide provided as a high-purity white to off-white solid for biochemical and cell biology research. It is commonly used to investigate lipid signaling, membrane properties, and apoptosis pathways, and can be formulated for in vitro assays and analytical studies.
High purity (98.0%) suitable for analytical and biological assays.
Molecular weight 551.93 and formula C35H69NO3 for accurate calculations.
Supplied as a solid powder for ease of handling and storage.
Available in small research pack sizes for low-volume experiments.
Powder stable at -20°C for long-term storage.
Recommended solvent storage at -80°C for prolonged sample preservation.
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C12 NBD ceramide (d18:1/12:0) is a long-chain fluorescent ceramide analog that can be used for the measurement of alkaline and neutral ceramidase activity.{14063} It is hydrolyzed efficiently by alkaline ceramidase from P. aeruginosa and by neutral ceramidase from mouse liver. In addition, alkaline and neutral ceramidases from a variety of mammalian cell lines also hydrolyze C12 NBD ceramide (d18:1/12:0). Acid ceramidase does not appear to utilize C12 NBD ceramide (d18:1/12:0) as a substrate. The possibility exists forC12 NBD ceramide (d18:1/12:0) to also be applied to the measurement of ceramide kinase and/or sphingomyelin synthase activity.
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Sphingomyelinase (SMase) or sphingomyelin phosphodiesterase catalyzes the hydrolytic cleavage of sphingolipid to phosphocholine and ceramide a second messenger involved in multiple cellular responses including the cellular response to stress. There are at least 5 types of SMases identified which are classified according to their cation dependence cellular location and pH optima for activity and include the acidic and neutral sphingomyelinase. Neutral SMases along with the acidic SMases are thought to be major contributors to the production of ceramide in response to cellular stress.
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Also available in 1 mg, 5 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. C14 Ceramide is an endogenous ceramide produced by ceramide synthetase 6, which can be used for Parkinson's research. Purity 99.63%
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