Sphingolipids
Medchemexpress LLC 17:1 Lyso PC | 1246304-62-0 | C25H50NO7P | 100 MG
17:1 Lyso PC is a liposome designed to simulate biological phospholipid membranes, utilized in constructing drug delivery systems for anti-cancer and anti-infection applications.
- Encapsulates highly polar water-soluble payloads
- Lipophilic payloads can integrate into the lipid bilayer
- Effective for delivering antisense oligonucleotides
- Addresses inefficient cellular uptake
- Addresses rapid degradation in the body
Medchemexpress LLC C16 PEG2000 ceramide | 212116-78-4 | MFCD02265697 | 99.4% | 2000 (Average) | (C2H4O)nC39H73NO6 | 5 MG
C16 PEG2000 ceramide is a polyethylene glycol-conjugated C16 ceramide (average PEG molecular weight 2000) used as a lipid component in delivery formulations and laboratory research. It is reported to induce autophagy and is commonly applied in studies of lipid-based carriers and cancer-related cellular assays.
- PEGylated C16 ceramide with average PEG molecular weight 2000.
- Functions as a lipid carrier for formulation and delivery studies.
- Reported to induce autophagy in cellular assays.
- High chemical purity suitable for research applications.
- Available in small milligram pack sizes for laboratory use.
Medchemexpress LLC N-Behenoyl-D-erythro-sphingosine | 27888-44-4 | C40H79NO3 | 1 MG
C22-Ceramide, also known as N-Behenoyl-D-erythro-sphingosine, is an endogenous bioactive sphingolipid. This compound has been observed to reduce the propensity of C16-ceramide channel formation in isolated rat liver mitochondria and in liposomes. It is primarily intended for research use.
- Endogenous bioactive sphingolipid
- Reduces C16-ceramide channel formation
- Potential for research into intrinsic apoptosis regulation
Medchemexpress LLC C22-Ceramide (N-Behenoyl-D-erythro-sphingosine) | 27888-44-4 | C40H79NO3 | 100 MG
C22-Ceramide is an endogenous bioactive sphingolipid that reduces the propensity of C16-ceramide channel formation in isolated rat liver mitochondria and in liposomes.
- Reduces C16-ceramide channel formation in isolated rat liver mitochondria
- Reduces C16-ceramide channel formation in liposomes
Cayman Chemical C12 NBD Ceramide d18 1 12 0
C12 NBD ceramide (d18:1/12:0) is a long-chain fluorescent ceramide analog that can be used for the measurement of alkaline and neutral ceramidase activity.{14063} It is hydrolyzed efficiently by alkaline ceramidase from P. aeruginosa and by neutral ceramidase from mouse liver. In addition, alkaline and neutral ceramidases from a variety of mammalian cell lines also hydrolyze C12 NBD ceramide (d18:1/12:0). Acid ceramidase does not appear to utilize C12 NBD ceramide (d18:1/12:0) as a substrate. The possibility exists forC12 NBD ceramide (d18:1/12:0) to also be applied to the measurement of ceramide kinase and/or sphingomyelin synthase activity.
Cayman Chemical C162 S-hydroxy CeramIde 1mg
A synthetic ceramide; has no effect on C6 glioma cell viability at concentrations up to 20 µM
Medchemexpress LLC C16 ceramide-1-phosphate (d18:1/16:0) (ammonium) | 1246303-22-9 | 98% | C34H71N2O6P | 500 UG
C16 Ceramide-1-phosphate (d18:1/16:0) (ammonium) is an ester product used as a laboratory chemical and for the manufacture of substances.
- Appears as a solid
- Stable under recommended storage conditions
- Store at -20°C, protect from light, and under nitrogen
- Suitable for laboratory use
Medchemexpress LLC C6 NBD ceramide | 94885-02-6 | MFCD00467024 | 99.3% | 575.74 g/mol | C30H49N5O6 | 1 MG
C6 NBD ceramide is a fluorescent short-chain ceramide analog used as a Golgi apparatus probe in live and fixed cells. It is cell-permeable and is metabolized to fluorescent sphingomyelin and glucosylceramide, enabling visualization of sphingolipid transport, Golgi morphology, and related cellular processes (Ex 466 nm, Em 536 nm).
- Provides bright green fluorescence for imaging (Ex 466 nm, Em 536 nm).
- Cell membrane permeable for live and fixed cell labeling.
- Metabolized to fluorescent sphingomyelin and glucosylceramide for metabolism studies.
- High purity (99.3%) for consistent experimental results.
- Supplied as a 1 mg vial suitable for small-scale assays.
- Store sealed at -20°C; in solvent, store at -80°C for up to 6 months or -20°C for up to 1 month.
Medchemexpress LLC C26 ceramide | 121459-09-4 | 99.9% | 678.17 g/mol | C44H87NO3 | 10 MG
C26-Ceramide is a long-chain ceramide lipid (N-hexacosanoylsphingosine) composed of one saturated and one unsaturated hydrophobic tail. It is provided as a high-purity biochemical reagent for lipid research and formulation studies, including lipid nanoparticle and liposome development.
- High purity (99.89%) suitable for research applications.
- Long-chain ceramide structure with a C26 acyl chain.
- Useful for lipid nanoparticle and liposome formulation studies.
- Supplied in research-scale quantities for assay and formulation work.
- Molecular formula C44H87NO3; molecular weight 678.17 g/mol.