Sphingolipids

A class of lipids containing a backbone of sphingoid bases, a set of aliphatic amino alcohols that includes sphingosine, a long-chain amino alcohol.

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Cayman Chemical C8 CeramIde-1-phosphated1810mg

A PINK1 activator increases levels of PINK1 and pUb in combination with FCCP in HeLa cells at 6.6 UM induces mitophagy in combination with FCCP in HeLa cells (EC50 0.44 UM) inhibits doxycycline-induced increases in the mitochondrial levels of insoluble OTC in HeLa cells at 25 or 50 UM decreases the midbrain levels of total a-synuclein and insoluble a-synuclein aggregates in a mouse model of Parkinson's disease induced by a-synuclein injection in the ipsilateral striatum at 50 mg/kg per day