Steroids and derivatives
Apexbio Technology LLC Cyproterone Acetate 427-51-0 250mg
Cyproterone Acetate (CAS 427-51-0) is a small-molecule antagonist targeting the androgen receptor (AR) It is designed to inhibit AR activation thereby suppressing androgen-mediated cellular signaling Cyproterone Acetate exerts its biological activity primarily through competitive binding to AR displacing endogenous androgen ligands and blocking receptor activation and downstream signaling In experimental assays Cyproterone Acetate demonstrates AR inhibition with an IC50 value of approximately 7 1 nM At higher concentrations (EC50 around 4 0 M) it may also exhibit partial agonist activity on the AR pathway Based on these pharmacological properties Cyproterone Acetate holds research potential in studies of androgen-dependent biological processes AR signaling mechanisms and hormone-sensitive pathologies such as prostate cancer or androgen-related metabolic conditions
Medchemexpress LLC Hydrocortisone cypionate | 508-99-6 | 486.64 | 1 ML
Hydrocortisone cypionate | 508-99-6 | 486.64 | 1 ML
Medchemexpress LLC Cortisone | 53-06-5 | 99.3% | 360.44 | 1 ML
Cortisone (17-Hydroxy-11-dehydrocorticosterone) is an oxidized metabolite of Cortisol, a Glucocorticoid. It functions as an immunosuppressant and anti-inflammatory agent. Cortisone can partially intervene in the binding of Glucocorticoid to the Glucocorticoid-receptor at high concentrations, and has been shown to attenuate apoptosis induced by Cortisol in peripheral-blood mononuclear cells (PBMCs) and decrease BCG lesions and tuberculin reactions in rabbits.
- Acts as an immunosuppressant
- Acts as an anti-inflammatory agent
- Attenuates apoptosis
- Decreases BCG lesions and tuberculin reactions
- Targets Glucocorticoid Receptor
- Is an endogenous metabolite
Medchemexpress LLC Hydrocortisone (Standard) | 50-23-7 | 362.46 | 100 MG
Hydrocortisone (Standard) is the analytical standard of Hydrocortisone. This product is intended for research and analytical applications. Hydrocortisone (Cortisol) is a steroid hormone or glucocorticoid secreted by the adrenal cortex.
- Analytical standard
- Intended for research and analytical applications
- Used as a reference standard in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS
- Steroid hormone or glucocorticoid secreted by the adrenal cortex
Medchemexpress LLC Prednisone (Standard) | 53-03-2 | 99.8% | 50 MG
Prednisone (Standard) is the analytical standard of Prednisone, intended for research and analytical applications. It is a corticosteroid agent with anti-inflammatory and immunosuppressive effects that can be used to study diseases related to systemic lupus erythematosus. This compound is of analytical standard grade, serving as a reference standard for assays.
- Intended for research and analytical applications
- Corticosteroid agent with anti-inflammatory and immunosuppressive effects
- Used to study diseases related to systemic lupus erythematosus
- Commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS
- Analytical standard grade
Medchemexpress LLC Hydrocortisone buteprate | 72590-77-3 | 99.3% | 488.6 g/mol | C28H40O7 | 5 MG
Hydrocortisone buteprate is a medium-potency, non-halogenated double-ester corticosteroid supplied as a solid analytical standard for laboratory research and analytical applications. The material is provided in a 5 mg package with high purity and is intended for research use only.
- Solid analytical standard supplied as a 5 mg package.
- High purity (99.3%).
- CAS number 72590-77-3.
- Chemical formula C28H40O7; molecular weight 488.6 g/mol.
- Used for corticosteroid research and topical formulation studies.
- Not for human or veterinary use; for laboratory research only.
Apexbio Technology LLC Dexamethasone acetate 1177-87-3 5g
Dexamethasone acetate a synthetic glucocorticoid acts by binding to glucocorticoid receptors influencing gene transcription to suppress inflammatory and immune responses By modulating cytokine production and inhibiting interleukin (IL) signaling pathways dexamethasone acetate serves as an interleukin receptor modulator Typically applied in research related to inflammation autoimmune diseases and cytokine-mediated cellular events it is extensively utilized in functional assays to understand receptor-ligand interactions signal transduction and therapeutic mechanisms Studies report variable IC50 values depending on cell type and assay conditions with typical IC50 ranges documented from 1-10 nM in receptor binding assays providing a reference concentration range for experimental designs
Medchemexpress LLC Cortisone (Standard) | 53-06-5 | 98.5% | 360.44 | 25 MG
Cortisone (Standard) is the analytical standard of Cortisone, intended for research and analytical applications. Cortisone (17-Hydroxy-11-dehydrocorticosterone), an oxidized metabolite of Cortisol (a Glucocorticoid), acts as an immunosuppressant and anti-inflammatory agent. It can partially intervene in the binding of Glucocorticoid to Glucocorticoid-receptor at high concentrations. This compound is a grade of analytical standard, commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
- Analytical standard for research and analytical applications
- Immunosuppressant and anti-inflammatory agent
- Suitable for qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS
Medchemexpress LLC Cortisone (Standard) | 53-06-5 | 98.51% | 360.44 | 50 MG
Cortisone (Standard) is the analytical standard of Cortisone, intended for research and analytical applications. It is an oxidized metabolite of Cortisol and acts as an immunosuppressant and anti-inflammatory agent. This compound is commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
- Analytical standard for research and analytical applications
- Oxidized metabolite of cortisol
- Acts as an immunosuppressant
- Acts as an anti-inflammatory agent
- Suitable for HPLC, GC, and MS experiments
Medchemexpress LLC Cortisone acetate | 50-04-4 | 99.9% | 402.48 | 25 G
Cortisone acetate, also known as Cortisone 21-acetate, is an oxidized metabolite of Cortisol, which is a Glucocorticoid. It functions as an immunosuppressant and anti-inflammatory agent. At high concentrations, cortisone acetate can partially interfere with the binding of Glucocorticoid to the Glucocorticoid-receptor.
- Functions as an immunosuppressant.
- Acts as an anti-inflammatory agent.
- Is an oxidized metabolite of cortisol.
- Can partially intervene in binding of glucocorticoid to glucocorticoid-receptor at high concentrations.
Apexbio Technology LLC Hydrocortisone(Synonyms: Cortisol, 17-Hydroxycorticosterone, Kendall's Compound F), 10mM (in 1mL DMSO), CAS: 50-23-7.
Hydrocortisone (CAS 50-23-7) is an endogenous glucocorticoid primarily synthesized and secreted by the adrenal cortex It exerts biological effects by binding glucocorticoid receptors altering gene expression involved in metabolic regulation immune response modulation and anti-inflammatory pathways Widely utilized in biomedical research hydrocortisone serves as a standard reference agent for investigating glucocorticoid receptor signaling inflammation models and stress response mechanisms