Purine nucleosides
Medchemexpress LLC 7-deaza-2'-deoxyadenosine | 60129-59-1 | 99.9% | 250.26 g/mol | C11H14N4O3 | 1 ML
7-deaza-2'-deoxyadenosine is a deoxynucleoside used as a biochemical reagent and building block for synthesis and oligonucleotide research.
- Ready-to-use 10 mM solution in DMSO.
- Supplied as 1 mL vial.
- High purity, reported as 99.9%.
- Molecular weight 250.26 g/mol.
- Molecular formula C11H14N4O3.
- CAS number 60129-59-1 for unambiguous identification.
TARGETMOL CHEMICALS INC 2 5 -Dideoxyadenosine 10MG
Also available in 1 mL, 1 mg, 5 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. 2',5'-Dideoxyadenosine is a potent and non-competitive adenylyl cyclase inhibitor, binding to the P-site with an IC50 of 3 uM. Purity 99.55%
Cambridge Isotope Laboratories 2-Deoxyadenosine monohydrate (13C10 98% 15N5 96-98%) 25 mg
2-Deoxyadenosine monohydrate (13C10 98% 15N5 96-98%) 25 mg
Medchemexpress LLC N6-Methyladenosine-13C | 2232870-66-3 | 99.9% | 282.26 | 1 MG
N6-Methyladenosine-13C is the 13C labeled isotope of N6-Methyladenosine. It is for research use only and not sold to patients.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC 2'-Deoxyguanosine | 961-07-9 | 100.0% | 267.25 | 25 MG
2'-Deoxyguanosine is a purine nucleoside with various biological activities. It can induce DNA division in mouse thymus cells and acts as a potent cell division inhibitor in plant cells. It also demonstrates antiproliferative and antiviral effects against several cell lines and viruses.
- Induces DNA division in mouse thymus cells.
- Acts as a potent cell division inhibitor in plant cells.
- Inhibits clonal growth of HL-60 and K562 leukemia cells.
- Exhibits antiviral activity against varicella zoster virus (VZV) Oka strain.
- Exhibits antiviral activity against human cytomegalovirus (HCMV) AD 169 strain.
- Exhibits antiviral activity against herpes simplex virus-1 VR-3 strain.
- Exhibits antiviral activity against herpes simplex virus-2 (HSV-2) Ms strain.
Cambridge Isotope Laboratories 2-Amino-2-deoxyadenosine 5-triphosphate NH4 (ribose-1 2 3 4 5-13C5 99%) (in solution) CP 95% 100 umol
2-Amino-2-deoxyadenosine 5-triphosphate NH4 (ribose-1 2 3 4 5-13C5 99%) (in solution) CP 95% 100 umol
Medchemexpress LLC 6-Thio-2'-Deoxyguanosine | 789-61-7 | 99.7% | 283.31 | 50 MG
6-Thio-2'-Deoxyguanosine is a nucleoside analogue that can be incorporated into de novo-synthesized telomeres by telomerase. It causes rapid cell death for the majority of cancer cell lines tested with IC50s between 0.7-2.9 μM. In A549 lung cancer cell-based mouse xenograft studies, it decreases tumor growth rate and increases telomere dysfunction in tumor cells in vivo.
- Nucleoside analogue
- Incorporated into de novo-synthesized telomeres by telomerase
- Results in rapid cell death for the vast majority of cancer cell lines tested with IC50s of between 0.7-2.9 μM
- Causes a decrease of the tumor growth rate in A549 lung cancer cell-based mouse xenograft studies
- Increases telomere dysfunction in tumor cells in vivo
Medchemexpress LLC 2'-Deoxyadenosine 5'-triphosphate disodium | 74299-50-6 | MFCD00080335 | 99.97% | 535.15 | 50 MG
2'-Deoxyadenosine 5'-triphosphate disodium is a nucleotide with important biological activities. It plays a key role in DNA synthesis and reverse transcription and is widely utilized in in vitro reactions in molecular biology research.
- Serves as a substrate for various polymerases
- Supports DNA synthesis
- Supports reverse transcription
- Suitable for in vitro reactions in molecular biology research
Medchemexpress LLC 2'-Deoxyadenosine monohydrate | 16373-93-6 | 99.89% | 269.26 | 5 G
2'-Deoxyadenosine monohydrate is an adenine nucleoside with multiple biological roles, including inhibiting glucose-stimulated insulin release and islet cyclic AMP (cAMP) accumulation. It activates caspase-3 and promotes apoptosis, and inhibits S-adenosyl-L-homocysteine hydrolase (SAHH) activity. It has shown an anticancer effect on colon cancer and appears as a white to off-white solid.
- Inhibits glucose-stimulated insulin release
- Inhibits glucose-stimulated increases in islet cyclic AMP (cAMP) accumulation
- Activates caspase-3
- Promotes apoptosis
- Inhibits S-adenosyl-L-homocysteine hydrolase (SAHH) activity
- Demonstrated inhibitory effect on the growth of various cells, including anticancer effect on colon cancer
- Appears as a white to off-white solid
Bioworld 2'-Deoxyadenosine Monohydrate, 10 g
A deoxyribonucleoside, may be used by some cells as an energy source under energy stress conditions and to affect cAMP levels. It is used in comparison studies of the functions of adenosine analogues on various biological processes. Specifications:Ultra Pure GradeEM (259nm, phosphate buffer, pH 7.0): >14,500Appearance: White crystalline powderChEBI : Not available.Crystal_Structure : Not available.InChI : Not available.InChIKey : Not available.Melting Point: 187-189 °CRTECS Number: AU7358600
Medchemexpress LLC N6,N6-dimethyladenosine | 2620-62-4 | MFCD00022822 | 100.0% | 295.29 g·mol⁻1 | C12H17N5O4 | 1 ML
N6,N6-dimethyladenosine is a modified ribonucleoside used as an analytical standard and research reagent. It is supplied as solid material or as a 10 mM solution in DMSO and is used in studies of RNA modification, cellular signaling (including AKT pathway modulation), and viral entry protein interactions.
- High purity (>99.9%) suitable for analytical use.
- Available as solid and 10 mM solution in DMSO for convenient handling.
- Molecular formula C12H17N5O4 and molecular weight 295.29 g·mol⁻1.
- Suitable for studies of RNA modification and cellular signaling.
- Certificate of analysis and safety data sheet available.
Cayman Chemical 2-DeoxyadenosIn-5-monphos 5g
A derivative of AMP that has been used in the synthesis of novel photoaffinity labels for incorporation into DNA and to study adenosine-based interactions during DNA synthesis and DNA damage
Medchemexpress LLC 2'-deoxyadenosine-5'-monophosphate | 653-63-4 | 99.2% | 331.22 | C10H14N5O6P | 25 MG
2'-Deoxyadenosine-5'-monophosphate (dAMP) is a deoxyribonucleotide used as an analytical standard and reference material for nucleic acid research, method validation, and chromatographic or mass-spectrometry assays. Supplied as a solid in amber glass packaging, it is intended for calibration, quantitation, and analytical method development.
- High purity analytical standard suitable for HPLC and MS.
- Purity confirmed by HPLC (99.15% reported by COA).
- Molecular formula C10H14N5O6P and molecular weight 331.22.
- Supplied in brown glass to protect from light and moisture.
- Intended for calibration, method validation, and quantitative analyses.