Purine nucleosides
Cayman Chemical 2-Fluoro-2-deoxyadenosIn 1g
A prodrug form of 2-F-adenine; reduces mean tumor weight in an E. coli purine nucleoside phosphorylase-expressing D54 glioblastoma mouse xenograft model at 100 mg/kg
Apexbio Technology LLC 2'-Deoxyguanosine 961-07-9 1g
2 -Deoxyguanosine (CAS 961-07-9) is a purine deoxyribonucleoside comprising guanine coupled to a deoxyribose moiety As an essential constituent of DNA it serves as a substrate in multiple nucleotide metabolism pathways Its interconversion with 2 -deoxyguanosine 5 -monophosphate is mediated by purine 5 -nucleotidase and deoxyguanosine kinase reflecting its role in nucleic acid turnover In biomedical research 2 -deoxyguanosine is utilized to study DNA synthesis repair mechanisms and enzymatic processes involving nucleoside metabolism Altered deoxyguanosine homeostasis has been implicated in purine nucleoside phosphorylase deficiency underscoring its significance in inherited metabolic disorders
Medchemexpress LLC Adenosine, 2-amino-2'-deoxy- | 4546-70-7 | MFCD00047240 | 99.6% | 266.26 g·mol⁻¹ | C10H14N6O3 | 5 G
2-Amino-2'-deoxyadenosine is a modified deoxyribonucleoside (CAS 4546-70-7) used as a building block in oligonucleotide synthesis and nucleic acid research. Supplied for research use only, it is offered in solid and solution formats and accompanied by analytical documentation to support quality and reproducibility.
- High purity (99.6%).
- Available in multiple sizes, including 5 g and solution formats.
- Molecular weight 266.26 g·mol⁻¹; formula C10H14N6O3.
- Certificate of analysis available for batch verification.
- Intended for research use only; not for human or veterinary use.
Medchemexpress LLC 2'-Deoxyguanosine-13C10,15N5 (monohydrate) | 2483830-26-6 | 99.8% | 5 MG
2'-Deoxyguanosine-13C10,15N5 (monohydrate) is the 13C and 15N labeled 2'-Deoxyguanosine monohydrate. It is an endogenous metabolite.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Incorporates stable heavy isotopes of hydrogen, carbon, and other elements.
- Deuteration has potential to affect pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Deoxyguanosine triphosphate trisodium solution | 93919-41-6 | 99.95% | 573.13 | 57.31 MG
Deoxyguanosine triphosphate (dGTP) trisodium solution (100mM) is a nucleotide precursor in cells for DNA synthesis. It is used in reverse transcription-polymerase chain reaction (RT-PCR) for DNA amplification.
- Nucleotide precursor for DNA synthesis.
- Used in reverse transcription-polymerase chain reaction (RT-PCR) for DNA amplification.
- High purity: 99.95%.
Medchemexpress LLC 2'-Deoxyadenosine-5'-triphosphate trisodium | 54680-12-5 | 99.0% | 557.13 | 5 ML
2'-Deoxyadenosine-5'-triphosphate trisodium is a raw material used by DNA polymerase to synthesize long DNA chains during DNA replication. It is also utilized in reverse transcription polymerase chain reaction (RT-PCR) for DNA amplification. This product is provided as an aqueous solution.
- Raw material for DNA synthesis
- Utilized in reverse transcription polymerase chain reaction (RT-PCR)
- Provided as an aqueous solution
Medchemexpress LLC 3′-Deoxyguanosine | 3608-58-0 | 97.0% | 267.25 | 5 MG
3′-Deoxyguanosine is a derivative of Guanosine. It interacts with human purine nucleoside phosphorylase through hydrogen bonding with residues like Glu201 and Asn243. This compound shows moderate displacement activity for [3H]-guanosine in rat meninges and is useful for studying the mechanism of guanosine receptors and purine metabolism.
- Derivative of Guanosine.
- Interacts with human purine nucleoside phosphorylase via hydrogen bonding.
- Exhibits moderate displacement activity for [3H]-guanosine in rat meninges.
- Useful for studying guanosine receptor mechanisms and purine metabolism.
- For research use only.
Medchemexpress LLC N6-Benzyladenosine | 4294-16-0 | 1 ML
N6-Benzyladenosine is an adenosine receptor agonist with cytoactive activity. It arrests the cell cycle at the G0/G1 phase and induces cell apoptosis. It also inhibits *T. gondii* adenosine kinase and glioma, making it suitable for various research applications.
- Adenosine receptor agonist
- Induces cell apoptosis
- Arrests cell cycle at G0/G1 phase
- Inhibits *T. gondii* adenosine kinase
- Exerts anti-glioma activity
- Suppresses clonogenic activity and growth of various neoplastic cells
- Potent inducer of apoptosis with caspase-3 and caspase-9 activation
- Induces chromatin condensation, apoptotic body formation, and DNA cleavage
Medchemexpress LLC 5'-Deoxyadenosine | 4754-39-6 | 99.9% | 251.24 | 10 MM * 1 ML
5'-Deoxyadenosine is an oxidized nucleoside found in the urine of normal subjects. It shows anti-orthopoxvirus activity.
- Oxidized nucleoside
- Found in the urine of normal subjects
- Shows anti-orthopoxvirus activity
- For research use only
- Available in solid and solution forms
- High purity (99.92%)
- Endogenous metabolite
- Human gut microbiota metabolites
![eMolecules 892-48-8 | 5'-CHLORO-5'-DEOXYADENOSINE | AstaTech | MFCD00049038 | 285.690 | C10H12ClN5O3 | 95.000 | Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CCl)[C@@H](O)[C@H]1O | 25g | 308519687](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000164417.jpg-250.jpg)
eMolecules 892-48-8 | 5'-CHLORO-5'-DEOXYADENOSINE | AstaTech | MFCD00049038 | 285.690 | C10H12ClN5O3 | 95.000 | Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CCl)[C@@H](O)[C@H]1O | 25g | 308519687
5'-CHLORO-5'-DEOXYADENOSINE | AstaTech | 892-48-8 | MFCD00049038 | 285.690 | C10H12ClN5O3 | 95.000 | Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CCl)[C@@H](O)[C@H]1O | 25g | 308519687
TARGETMOL CHEMICALS INC 3-DEOXYGUANOSINE 100MG
Also available in 10 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. 3'-Deoxyguanosine is a ligand that can be complexed with enzymes such as purine nucleoside phosphorylase and receptors. purity: 98%
Apexbio Technology LLC 2-Deoxyadenosine 958-09-8 500mg
2-Deoxyadenosine (CAS 958-09-8) is a synthetic purine nucleoside analog that functions as a demethylated nucleoside in biological systems Structurally similar to adenosine but lacking a hydroxyl group at the 2 position it selectively pairs with deoxythymidine during DNA synthesis 2-Deoxyadenosine influences regulatory pathways associated with DNA replication and repair serving as a molecular probe to study these processes It is extensively utilized in molecular biology and genomics for investigating DNA synthesis repair mechanisms and the dynamics of nucleic acid metabolism