Purine nucleosides
Medchemexpress LLC 2'-Deoxyguanosine-13C10,15N5 monohydrate | 2483830-26-6 | 99.8% | 1 MG
2'-Deoxyguanosine-13C10,15N5 (monohydrate) is the 13C and 15N labeled 2'-Deoxyguanosine monohydrate, which is an endogenous metabolite. It is for research use only and not sold to patients.
- Used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules for quantitation during the drug development process.
- Deuteration has potential to affect pharmacokinetic and metabolic profiles of drugs.
Chemscene ChemScene | 2'-Deoxyadenosine monohydrate | 100G | CS-W012399 | 0.98 | 16373-93-6| MFCD00149364 | 269.26
ChemScene | 2'-Deoxyadenosine monohydrate | 100G | CS-W012399 | 0.98 | 16373-93-6| MFCD00149364 | 269.26
Medchemexpress LLC 2'-Deoxyadenosine monohydrate | 16373-93-6 | 99.9% | 269.26 | 25 G
2'-Deoxyadenosine monohydrate is an adenine nucleoside that inhibits glucose-stimulated insulin release. It also inhibits glucose-stimulated increases in islet cyclic AMP (cAMP) accumulation, activates caspase-3, promotes apoptosis, inhibits the activity of S-adenosyl-L-homocysteine hydrolase (SAHH), and inhibits the growth of various cells, demonstrating an anticancer effect on colon cancer.
- Inhibits glucose-stimulated insulin release.
- Inhibits glucose-stimulated increases in islet cyclic AMP accumulation.
- Activates caspase-3 and promotes apoptosis.
- Inhibits the activity of S-adenosyl-L-homocysteine hydrolase (SAHH).
- Inhibits the growth of various cells.
- Has an anticancer effect on colon cancer.
- Appears as a solid, white to off-white substance.
- Initial source is microorganisms (Streptomyces jiujiangensis).
Apexbio Technology LLC 6-O-Propynyl-2-deoxyguanosine 1mL(10 mM in DMSO)
6-O-Propynyl-2-deoxyguanosine (CAS 1640051-47-3) is a modified nucleoside featuring an alkyne functional group at the 6-position of deoxyguanosine This structural modification enables its use in bioorthogonal click chemistry reactions facilitating site-specific labeling and conjugation in nucleic acid research The alkynyl group serves as a chemical handle for copper-catalyzed azide-alkyne cycloaddition allowing researchers to attach probes or other functional molecules 6-O-Propynyl-2-deoxyguanosine is utilized for studying DNA structure dynamics and for the development of modified oligonucleotides in biochemical and molecular biology assays
Cambridge Isotope Laboratories 2-Deoxyguanosine 5-triphosphate ammonium salt (13C10 98% 15N5 96-98%) CP 90% (in solution) 20 umol
2-Deoxyguanosine 5-triphosphate ammonium salt (13C10 98% 15N5 96-98%) CP 90% (in solution) 20 umol
Cambridge Isotope Laboratories 2-Deoxyguanosine 5-triphosphate ammonium salt (15N5 98-99%) CP 90% (in solution) 20 umol
2-Deoxyguanosine 5-triphosphate ammonium salt (15N5 98-99%) CP 90% (in solution) 20 umol
Medchemexpress LLC Adenosine, 5'-deoxy- | 4754-39-6 | 99.9% | 251.246 | 50 MG
5'-Deoxyadenosine is an oxidized nucleoside found in the urine of normal subjects. It shows anti-orthopoxvirus activity.
- Oxidized nucleoside
- Found in the urine of normal subjects
- Shows anti-orthopoxvirus activity
Cambridge Isotope Laboratories 8-Hydroxy-2-deoxyguanosine (15N5 98%) CP 95% 1 mg
8-Hydroxy-2-deoxyguanosine (15N5 98%) CP 95% 1 mg
Cayman Chemical N6-Methyl-2-deoxyadenosIn 50mg
A nucleoside and inducer of EPC proliferation; stimulates the proliferation of EPCs isolated from mouse fetal livers and colony formation of isolated mouse bone marrow cell-derived progenitor cells at 10 and 100 µM; accumulates along promoters and gene coding sequences in activated mouse prefrontal cortical neurons; is associated with activation at the Bdnf promoter
Medchemexpress LLC 8-Bromo-2'-deoxyadenosine | 14985-44-5 | ≥98.0% | 330.14 | 100 MG
8-Bromo-2'-deoxyadenosine is a purine nucleoside analog. These analogs possess broad antitumor activity against indolent lymphoid malignancies. Their anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis.
- Purine nucleoside analog
- Broad antitumor activity
- Inhibits DNA synthesis
- Induces apoptosis
Medchemexpress LLC 2'-Deoxyguanosine | 961-07-9 | 99.9% | 267.25 | 10 G
2'-Deoxyguanosine is a purine nucleoside with diverse biological activities, known to induce DNA division in mouse thymus cells and act as a potent cell division inhibitor in plant cells. It also demonstrates inhibitory effects on the clonal growth of HL-60 and K562 leukemia cells, with observed IC50 values of 50 and 80 μM, respectively. This compound typically appears as a solid, ranging from white to off-white in color.
- Endogenous metabolite
- Harmful if swallowed
- Causes skin irritation
- Causes serious eye irritation
- May cause respiratory irritation
Medchemexpress LLC 3′-Deoxyguanosine | 3608-58-0 | 97.0% | 267.25 | 10 MG
3′-Deoxyguanosine is a derivative of Guanosine that interacts with human purine nucleoside phosphorylase through hydrogen bonding. It demonstrates moderate displacement activity for [3H]-guanosine in rat meninges. This product is for research use only and not sold to patients.
- Derivative of guanosine
- Interacts with human purine nucleoside phosphorylase
- Useful for studying guanosine receptors
- Useful for studying purine metabolism
- Exhibits moderate displacement activity for [3H]-guanosine in rat meninges
Medchemexpress LLC 3′-Deoxyguanosine | 3608-58-0 | MFCD28041154 | 97.0% | 267.25 | 100 MG
3′-Deoxyguanosine is a derivative of Guanosine. It interacts with human purine nucleoside phosphorylase via hydrogen bonding with residues such as Glu201 and Asn243. It exhibits moderate displacement activity for [3H]-guanosine in rat meninges and is useful for studying the mechanism of guanosine receptors and purine metabolism.
- Useful for studying guanosine receptors
- Used in research on purine metabolism
- Interacts via hydrogen bonding with human purine nucleoside phosphorylase