Purine nucleosides
TARGETMOL CHEMICALS INC 6-THIO-2-DEOXYGUANOSINE 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. 6-Thio-2'-Deoxyguanosine ((beta)-TGdR) is a nucleoside analog and telomerase substrate. purity: 99%
Cayman Chemical N6-benzoyl-2-DeoxyadenosIn 1g
An agonist of mGluRs (EC50s 15 2 40 23 and 82 UM for mGluR1 -2 -3 -5 and -6 respectively in CHO cells expressing recombinant receptors and 800 UM for mGluR4 in baby hamster kidney cells) increases cAMP accumulation in adult rat cerebral cortex slices (EC50 47 8 UM) but not in isolated rat embryonic neurons or neonatal glial cells at 1-1000 UM increases phosphoinositide hydrolysis in neonatal rat cerebral cortex and hippocampal slices at 10-1000 UM induces convulsions in neonatal rats (ED50 100 mg/kg) an effect that can be reversed by administration of the NMDA receptor antagonists LY233053 and LY274614
Cayman Chemical N6-benzoyl-2-DeoxyadenosIn 10g
A small molecule that induces proliferation of primary human hepatocytes in vitro
Cayman Chemical 5-chloro-5-DeoxyadenosIn 1g
An internal standard for the quantification of acetaminophen by GC- or LC-MS
Cayman Chemical 2-DeoxyadenosIn-5-monphos 1g
A glycoside scavenges DPPH and ABTS radicals (EC50s 81.54 and 30.94 Ug/ml respectively in cell-free assays) inhibits apoptosis and production of ROS induced by AB (23-35) in SH-SY5Y neuroblastoma cells at 50 and 100 UM decreases infarct volume by 17.9 in a rat model of focal cerebral ischemia-reperfusion injury induced by MCAO at 12 mg/kg increases survival and reduces plasma ALT AST TNF-a and MDA levels in a mouse model of acetaminophen-induced liver injury
Cayman Chemical 2-Fluoro-2-deoxyadenosIn 500mg
An ionizable cationic lipid (pKa 7.12) intravenous administration of LNPs containing (S)-C12-200 and encapsulating mRNA encoding Cre recombinase increase the percentage of tdTomato hepatocytes endothelial cells and Kupffer cells in the livers of Ai14 mice greater than (R)-C12-200-containing and Cre mRNA-encapsulating LNPs
Cayman Chemical N6-Methyl-2-deoxyadenosIn 10mg
A polyphenol flavonoid dimer with diverse biological activities binds to PlGF and VEGF (Kds 394 and 476 nM respectively) increases the activity of JAK2 (EC50 660 nM) scavenges superoxide radicals (IC50 14.7 UM) inhibits the cytopathic effects of HIV-1 in MT-4 cells (IC50 14 Ug/ml) increases the proliferation of isolated mouse splenocytes and peritoneal macrophages from 25-100 UM and DAMI megakaryoblasts (EC50 8.58 UM) prevents decreases in the number of platelets in peripheral blood and megakaryocytes in the bone marrow in a mouse model of carboplatin-induced thrombocytopenia at 50 mg/kg
Cayman Chemical N6-Methyl-2-deoxyadenosIn 50mg
An internal standard for the quantification of indole-3-acetic acid by GC- or LC-MS
Sigma Aldrich Fine Chemicals Biosciences 5-Deoxyadenosine methylthi25MG
5-Deoxyadenosine methylthi25MG
Thermo Scientific Chemicals 2'-Deoxyguanosine hydrate, 99%
CAS: 207121-55-9 Molecular Formula: C10H13N5O4 Molecular Weight (g/mol): 267.25 MDL Number: MFCD00150760 InChI Key: YKBGVTZYEHREMT-DWFKHXNSNA-N Synonym: 2'-deoxyguanosine,deoxyguanosine,guanine deoxyriboside,2-deoxyguanosine,guanosine, 2'-deoxy,guanine deoxy nucleoside,2'-deoxy-guanosine,2;-deoxyguanosine,unii-g9481n71ro,guanine, 9-2-deoxy-beta-d-erythro-pentofuranosyl PubChem CID: 187790 ChEBI: CHEBI:17172 IUPAC Name: 2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one SMILES: NC1=NC2=C(N=CN2[C@H]2C[C@H](O)[C@@H](CO)O2)C(=O)N1
2'-Deoxyadenosine Monohydrate, Thermo Scientific™
CAS: 16373-93-6 Molecular Formula: C10H13N5O3 Molecular Weight (g/mol): 251.25 MDL Number: MFCD00149364 InChI Key: OLXZPDWKRNYJJZ-YUZWJPFSNA-N Synonym: 2'-deoxyadenosine monohydrate,2r,3s,5r-5-6-amino-9h-purin-9-yl-2-hydroxymethyl tetrahydrofuran-3-ol hydrate,2r,3s,5r-5-6-amino-9h-purin-9-yl-2-hydroxymethyl tetrahydrofuran-3-ol hydrate,2'-deoxyadenosine hydrate,2'-deoxyadenosine hydrate,2-deoxyadenosine hydrate,9-2-deoxy-,9-2-deoxy-,deoxyadenosine monohydrate,deoxyadenosine monohydrate,2-deoxyadenosine monohydrate PubChem CID: 9549172 IUPAC Name: (2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-2-(hydroxymethyl)oxolan-3-ol SMILES: NC1=C2N=CN([C@H]3C[C@H](O)[C@@H](CO)O3)C2=NC=N1
2'-Deoxyguanosine, 99 to 100%, MP Biomedicals™
CAS: 961-07-9 Molecular Formula: C10H13N5O4 Molecular Weight (g/mol): 267.25 MDL Number: MFCD00150760 InChI Key: YKBGVTZYEHREMT-DWFKHXNSNA-N Synonym: 2'-deoxyguanosine,deoxyguanosine,guanine deoxyriboside,2-deoxyguanosine,guanosine, 2'-deoxy,guanine deoxy nucleoside,2'-deoxy-guanosine,2;-deoxyguanosine,unii-g9481n71ro,guanine, 9-2-deoxy-beta-d-erythro-pentofuranosyl PubChem CID: 187790 ChEBI: CHEBI:17172 IUPAC Name: 2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purin-6-one SMILES: NC1=NC2=C(N=CN2[C@H]2C[C@H](O)[C@@H](CO)O2)C(=O)N1
8-Bromo-2'-deoxyguanosine 98.0+%, TCI America™
CAS: 13389-03-2 Molecular Formula: C10H12BrN5O4 Molecular Weight (g/mol): 346.14 MDL Number: MFCD01630971 InChI Key: MKDXZFVCXWXGBQ-QXZWWJJYNA-N PubChem CID: 10947964 ChEBI: CHEBI:61072 IUPAC Name: 2-amino-8-bromo-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purin-6-one SMILES: NC1=NC2=C(N=C(Br)N2[C@H]2C[C@H](O)[C@@H](CO)O2)C(=O)N1