Purine nucleosides
Medchemexpress LLC 8-Bromo-2'-deoxyadenosine | 14985-44-5 | ≥98.0% | 330.14 | 100 MG
8-Bromo-2'-deoxyadenosine is a purine nucleoside analog. These analogs possess broad antitumor activity against indolent lymphoid malignancies. Their anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis.
- Purine nucleoside analog
- Broad antitumor activity
- Inhibits DNA synthesis
- Induces apoptosis
Medchemexpress LLC 6-Thio-2'-Deoxyguanosine | 789-61-7 | 99.7% | 283.31 | 25 MG
6-Thio-2'-Deoxyguanosine is a nucleoside analogue that can be incorporated into de novo-synthesized telomeres by telomerase. This product is for research use only and not for sale to patients.
- Treatment results in rapid cell death for the vast majority of cancer cell lines tested, with IC50s between 0.7-2.9 μM.
- In A549 lung cancer cell-based mouse xenograft studies, it causes a decrease of the tumor growth rate, superior to that observed with 6-thioguanine treatment.
- It increases telomere dysfunction in tumor cells in vivo.
Sigma Aldrich Fine Chemicals Biosciences 2 Deoxyadenosine monohydra25G
2 Deoxyadenosine monohydra25G
Medchemexpress LLC 2'-deoxyguanosine-13C monohydrate | 478511-26-1 | MFCD00080300 | 99.9% | 286.25 g/mol | C9(13)CH15N5O5 | 10 MG
2'-Deoxyguanosine-13C monohydrate is the carbon-13 isotopically labeled form of 2'-deoxyguanosine provided as the monohydrate solid for analytical and research applications, including metabolic flux analysis and isotope-tracing studies. The material is supplied with documentation (COA, SDS) and is intended for research use only.
- 13C labeled 2'-deoxyguanosine.
- Monohydrate solid form.
- Purity: 99.9% (HPLC).
- Molecular weight: 286.25 g/mol.
- Chemical formula: C9(13)CH15N5O5.
- CAS number: 478511-26-1.
- Typical pack size: 10 mg.
- Documentation available: COA and SDS for handling and storage.
- For research use only; not for human use.
Cayman Chemical 5-chloro-5-DeoxyadenosIn 1g
A nucleoside analog used as a substrate in the biosynthesis of the anticancer agent salinosporamide A
Apexbio Technology LLC 6-O-Propynyl-2-deoxyguanosine 1mL(10 mM in DMSO)
6-O-Propynyl-2-deoxyguanosine (CAS 1640051-47-3) is a modified nucleoside featuring an alkyne functional group at the 6-position of deoxyguanosine This structural modification enables its use in bioorthogonal click chemistry reactions facilitating site-specific labeling and conjugation in nucleic acid research The alkynyl group serves as a chemical handle for copper-catalyzed azide-alkyne cycloaddition allowing researchers to attach probes or other functional molecules 6-O-Propynyl-2-deoxyguanosine is utilized for studying DNA structure dynamics and for the development of modified oligonucleotides in biochemical and molecular biology assays
Medchemexpress LLC 2'-deoxyguanosine | 961-07-9 | MFCD00080300 | 99.2% | 267.24 g/mol | C10H13N5O4 | 10 MG
2'-Deoxyguanosine (standard) is the analytical standard of 2'-deoxyguanosine, a purine nucleoside used as an analytical reference and research reagent. Supplied as a high-purity solid, it is intended for analytical assays, method development, and quantitative reference applications.
- Analytical standard suitable for quantitative assays and calibration.
- High purity (99.2%) for reliable analytical results.
- Molecular weight 267.24 g/mol; formula C10H13N5O4 for accurate identification.
- Available in small pack sizes for method development and trace analyses.
- Supplied with certificate of analysis and recommended storage guidance.
Sigma Aldrich Fine Chemicals Biosciences 2'-Deoxyguanosine monohydrate 99-100% | 312693-72-4 | MFCD00150760 | 5G
2'-Deoxyguanosine monohydrate 99-100% | Purity: 99-100% | Mol Wt: 285.26 | 312693-72-4 | MFCD00150760 | 5G
Medchemexpress LLC 2'-Deoxyguanosine monohydrate | 312693-72-4 | 99.7% | 10 G
2'-Deoxyguanosine monohydrate is a nucleoside composed of guanine and 2'-deoxyribose, and it is one of the basic structural units of DNA. The oxidation products of 2'-Deoxyguanosine monohydrate may participate in DNA damage, which in turn may affect gene expression or induce cancer.
- Composed of guanine and 2'-deoxyribose.
- Basic structural unit of DNA.
- Oxidation products may participate in DNA damage.
- Can affect gene expression or induce cancer.
- High purity of 99.70%.
- Ships at room temperature.
- Store solid at 4°C, sealed, away from moisture.
- Store in solvent at -80°C for 6 months or -20°C for 1 month, sealed, away from moisture.
Medchemexpress LLC Deoxyguanosine triphosphate trisodium solution | 93919-41-6 | 99.95% | 573.13 | 28.66 MG
Deoxyguanosine triphosphate (dGTP) trisodium solution (100mM) is a nucleotide precursor in cells for DNA synthesis. It is used in reverse transcription-polymerase chain reaction (RT-PCR) for DNA amplification. Deoxyguanosine triphosphate is abnormally elevated in the red blood cells of individuals with immunodeficiency related to purine nucleoside phosphorylase deficiency, and it can be regarded as a potential toxic metabolite.
- Nucleotide precursor for DNA synthesis.
- Used in reverse transcription-polymerase chain reaction (RT-PCR) for DNA amplification.
Medchemexpress LLC 2'-deoxyadenosine-5'-monophosphate | 653-63-4 | MFCD00005753 | 99.6% | 331.22 g/mol | C10H14N5O6P | 1 ML
2'-Deoxyadenosine-5'-monophosphate (dAMP) is a deoxynucleotide used in biochemical and molecular biology research as an adenine-containing monophosphate component of DNA. It is used to study DNA synthesis, nucleotide interactions, and DNA damage/repair. The compound is supplied as a solid and as a ready-to-use 10 mM solution in DMSO for assay use.
- Adenine nucleoside monophosphate for DNA research.
- Available as solid or 10 mM solution in DMSO for immediate use.
- High purity suitable for biochemical assays.
- Compatible with DNA synthesis and damage/repair studies.
- Formula C10H14N5O6P and molecular weight 331.22 g/mol; CAS 653-63-4 for identification.
Medchemexpress LLC 3′-Deoxyguanosine | 3608-58-0 | 97.0% | 267.25 | 10 MG
3′-Deoxyguanosine is a derivative of Guanosine that interacts with human purine nucleoside phosphorylase through hydrogen bonding. It demonstrates moderate displacement activity for [3H]-guanosine in rat meninges. This product is for research use only and not sold to patients.
- Derivative of guanosine
- Interacts with human purine nucleoside phosphorylase
- Useful for studying guanosine receptors
- Useful for studying purine metabolism
- Exhibits moderate displacement activity for [3H]-guanosine in rat meninges
Medchemexpress LLC 3′-Deoxyguanosine | 3608-58-0 | MFCD28041154 | 97.0% | 267.25 | 100 MG
3′-Deoxyguanosine is a derivative of Guanosine. It interacts with human purine nucleoside phosphorylase via hydrogen bonding with residues such as Glu201 and Asn243. It exhibits moderate displacement activity for [3H]-guanosine in rat meninges and is useful for studying the mechanism of guanosine receptors and purine metabolism.
- Useful for studying guanosine receptors
- Used in research on purine metabolism
- Interacts via hydrogen bonding with human purine nucleoside phosphorylase